Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 12904671 | . | C | A | CCDS7810.2:NM_021961.5:c.698tCg>tAg_NP_068780.2:p.233S>* | Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7cmm | 1 | P28347 | 99.55 | 1e-167 |
X-RAY |
2021-02-03 | SER | A:37 | A:233 | 64.0 | 0.557 | E | -135.5 | 125.5 | 64.0 | 0.557 | 0.0 | ||||||
| SER | B:37 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| SER | C:37 | C:233 | 68.0 | 0.591 | -140.9 | 50.3 | NA | NA | NA | ||||||||||||||
| SER | D:37 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4re1 | 1 | P28347 | 99.54 | 3e-166 |
X-RAY |
2014-11-19 | SER | A:27 | A:218 | 48.0 | 0.417 | E | -122.9 | 126.7 | 48.0 | 0.417 | 0.0 |
HOH |
3.666 |
O |
O |
||
| SER | B:27 | B:218 | 48.0 | 0.417 | E | -120.9 | 124.5 | NA | NA | NA | |||||||||||||
| 3kys | 1 | P28347 | 100.0 | 4e-166 |
X-RAY |
2010-02-23 | SER | A:26 | A:218 | 23.0 | 0.2 | E | -132.8 | 124.7 | 23.0 | 0.2 | 0.0 |
HOH |
8.647 |
O |
O |
||
| SER | C:26 | C:218 | 24.0 | 0.209 | E | -134.9 | 123.9 | NA | NA | NA | |||||||||||||
| 6im5 | 1 | P28347 | 99.55 | 3e-165 |
X-RAY |
2019-02-06 | SER | A:40 | A:233 | 32.0 | 0.278 | E | -140.8 | 121.5 | 32.0 | 0.278 | 0.0 |
HOH |
6.490 |
O |
O |
||
| SER | B:40 | B:233 | 29.0 | 0.252 | E | -134.1 | 120.8 | NA | NA | NA | |||||||||||||
| 6hil | 1 | P28347 | 99.54 | 4e-165 |
X-RAY |
2019-04-03 | SER | A:26 | A:218 | 35.0 | 0.304 | -127.7 | 125.0 | 35.0 | 0.304 | 0.0 |
HOH |
4.375 |
OG |
O |
|||
| SER | C:26 | D:218 | 26.0 | 0.226 | -133.2 | 118.0 | NA | NA | NA | ||||||||||||||
| SER | E:26 | B:218 | 35.0 | 0.304 | E | -131.5 | 127.7 | NA | NA | NA | |||||||||||||
| SER | G:26 | C:218 | 35.0 | 0.304 | E | -130.3 | 130.0 | NA | NA | NA | |||||||||||||
| 7li5 | 1 | E9PKB7 | 100.0 | 5e-164 |
X-RAY |
2022-02-02 | SER | A:29 | A:233 | 58.0 | 0.504 | E | -130.1 | 128.3 | 58.0 | 0.504 | 0.0 |
HOH |
6.880 |
C |
O |
||
| SER | B:29 | B:233 | 51.0 | 0.443 | E | -137.1 | 128.5 | NA | NA | NA | |||||||||||||
| 6ge3 | 1 | Q15561 | 81.74 | 5e-136 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 47.0 | 0.336 | E | -130.8 | 121.2 | 47.0 | 0.336 | 0.0 |
HOH |
6.369 |
N |
O |
||
| 6gec | 1 | Q15561 | 81.74 | 5e-136 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 50.0 | 0.357 | E | -129.9 | 122.4 | 50.0 | 0.357 | 0.0 |
HOH |
3.322 |
CG2 |
O |
||
| 4ln0 | 1 | Q62296 | 82.19 | 5e-136 |
X-RAY |
2014-02-26 | THR | A:29 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | B:29 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6l9f | 1 | Q62296 | 82.19 | 5e-136 |
X-RAY |
2019-12-11 | THR | A:29 | A:234 | 66.0 | 0.471 | -137.4 | 126.2 | 66.0 | 0.471 | 0.0 |
HOH |
2.506 |
OG1 |
O |
|||
| THR | C:29 | B:234 | 55.0 | 0.393 | E | -140.2 | 120.3 | NA | NA | NA | |||||||||||||
| 6sba | 1 | Q62296 | 82.19 | 1e-135 |
X-RAY |
2020-09-30 | THR | A:28 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6ge5 | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 49.0 | 0.35 | E | -127.0 | 123.1 | 49.0 | 0.35 | 0.0 |
HOH |
2.642 |
OG1 |
O |
||
| 6geg | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 47.0 | 0.336 | E | -129.5 | 123.1 | 47.0 | 0.336 | 0.0 |
HOH |
2.655 |
OG1 |
O |
||
| 6gek | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 52.0 | 0.371 | E | -129.2 | 125.5 | 52.0 | 0.371 | 0.0 |
HOH |
7.190 |
O |
O |
||
| THR | C:26 | B:241 | 50.0 | 0.357 | -135.2 | 123.5 | NA | NA | NA | ||||||||||||||
| 3jua | 1 | Q62296 | 82.11 | 4e-135 |
X-RAY |
2010-02-23 | THR | A:27 | A:234 | 83.0 | 0.593 | E | -136.9 | 133.4 | 83.0 | 0.593 | 0.0 |
HOH |
7.563 |
N |
O |
||
| THR | C:27 | C:234 | 76.0 | 0.543 | E | -133.9 | 133.6 | NA | NA | NA | |||||||||||||
| THR | E:27 | E:234 | 59.0 | 0.421 | E | -123.2 | 139.5 | NA | NA | NA | |||||||||||||
| THR | G:27 | G:234 | 92.0 | 0.657 | E | -149.8 | 125.6 | NA | NA | NA | |||||||||||||
| 5xjd | 1 | Q62296 | 82.11 | 4e-135 |
X-RAY |
2018-01-24 | THR | A:27 | A:234 | 64.0 | 0.457 | -117.9 | 130.5 | 64.0 | 0.457 | 0.0 |
HOH |
7.726 |
N |
O |
|||
| THR | B:27 | B:234 | 59.0 | 0.421 | -118.7 | 130.9 | 59.0 | 0.421 | 0.0 |
HOH |
7.456 |
N |
O |
||||||||||
| 6ge4 | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 50.0 | 0.357 | E | -130.7 | 128.1 | 50.0 | 0.357 | 0.0 |
HOH |
6.933 |
C |
O |
||
| 6gee | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 49.0 | 0.35 | E | -129.5 | 119.8 | 49.0 | 0.35 | 0.0 |
HOH |
3.329 |
CG2 |
O |
||
| 6hik | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2019-04-03 | THR | A:26 | A:241 | 49.0 | 0.35 | E | -130.1 | 118.8 | 49.0 | 0.35 | 0.0 |
HOH |
2.643 |
OG1 |
O |
||
| 5gn0 | 1 | Q62296 | 82.11 | 6e-135 |
X-RAY |
2017-05-31 | THR | A:32 | A:234 | 63.0 | 0.45 | -124.1 | 136.7 | 63.0 | 0.45 | 0.0 | |||||||
| THR | B:32 | B:234 | 62.0 | 0.443 | -132.5 | 135.1 | NA | NA | NA | ||||||||||||||
| THR | C:32 | C:234 | 48.0 | 0.343 | -134.5 | 136.9 | NA | NA | NA | ||||||||||||||
| THR | D:32 | D:234 | 61.0 | 0.436 | -125.6 | 136.2 | NA | NA | NA | ||||||||||||||
| 5oaq | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2017-10-11 | THR | A:27 | A:241 | 48.0 | 0.343 | E | -134.4 | 122.7 | 48.0 | 0.343 | 0.0 |
HOH |
6.732 |
C |
O |
||
| 6q2x | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2019-07-03 | THR | A:27 | A:241 | 48.0 | 0.343 | E | -131.2 | 119.9 | 48.0 | 0.343 | 0.0 |
HOH |
6.795 |
C |
O |
||
| 6q36 | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2019-07-03 | THR | A:27 | A:241 | 51.0 | 0.364 | E | -134.3 | 120.9 | 28.0 | 0.2 | 0.164 |
B:Q15561:0.164 |
HOH |
2.670 |
OG1 |
O |
|
| THR | B:27 | B:241 | 52.0 | 0.371 | E | -126.7 | 124.9 | 28.0 | 0.2 | 0.171 |
A:Q15561:0.171 |
HOH |
6.424 |
CG2 |
O |
||||||||
| 5z2q | 4 | Q62296 | 82.49 | 1e-134 |
X-RAY |
2018-01-31 | THR | D:36 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5z2q | 3 | Q62296 | 82.49 | 1e-134 |
X-RAY |
2018-01-31 | THR | C:34 | A:234 | 116.0 | 0.829 | -66.0 | -57.0 | NA | NA | NA | |||||||
| 6ge6 | 1 | Q15561 | 80.82 | 2e-134 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 48.0 | 0.343 | E | -129.2 | 119.4 | 48.0 | 0.343 | 0.0 |
HOH |
3.275 |
CG2 |
O |
||
| 6gei | 1 | Q15561 | 80.82 | 2e-134 |
X-RAY |
2018-09-19 | THR | A:26 | A:241 | 51.0 | 0.364 | E | -127.4 | 122.9 | 51.0 | 0.364 | 0.0 |
HOH |
2.649 |
OG1 |
O |
||
| 6sen | 1 | Q15561 | 81.19 | 4e-134 |
X-RAY |
2019-11-20 | THR | A:27 | A:241 | 46.0 | 0.329 | E | -132.5 | 124.4 | 46.0 | 0.329 | 0.0 |
HOH |
2.638 |
OG1 |
O |
||
| THR | B:27 | B:241 | 54.0 | 0.386 | E | -127.6 | 126.7 | NA | NA | NA | |||||||||||||
| 6seo | 1 | Q15561 | 81.19 | 4e-134 |
X-RAY |
2019-11-20 | THR | A:27 | A:241 | 62.0 | 0.443 | -116.8 | 130.9 | 62.0 | 0.443 | 0.0 |
HOH |
7.381 |
O |
O |
|||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p28347-f1 | 1 | P28347 | 100.0 | 0.0 | SER | A:233 | A:233 | 54.0 | 0.47 | E | -133.7 | 123.9 | |