Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 12923649 | . | G | A | CCDS7810.2:NM_021961.5:c.862Gta>Ata_NP_068780.2:p.288V>I | Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7cmm | 1 | P28347 | 99.55 | 1e-167 |
X-RAY |
2021-02-03 | VAL | A:92 | A:288 | 0.0 | 0.0 | E | -122.5 | 132.2 | 0.0 | 0.0 | 0.0 |
KK9 |
8.314 |
CG1 |
C14 |
||
| VAL | B:92 | B:288 | 0.0 | 0.0 | E | -136.0 | 110.5 | NA | NA | NA | |||||||||||||
| VAL | C:92 | C:288 | 0.0 | 0.0 | E | -121.9 | 131.9 | NA | NA | NA | |||||||||||||
| VAL | D:92 | D:288 | 0.0 | 0.0 | E | -134.4 | 108.7 | NA | NA | NA | |||||||||||||
| 4re1 | 1 | P28347 | 99.54 | 3e-166 |
X-RAY |
2014-11-19 | VAL | A:82 | A:273 | 0.0 | 0.0 | E | -119.0 | 124.9 | 0.0 | 0.0 | 0.0 |
CL HOH |
9.575 7.035 |
CG1 CG1 |
CL O |
||
| VAL | B:82 | B:273 | 0.0 | 0.0 | E | -120.6 | 123.0 | NA | NA | NA | |||||||||||||
| 3kys | 1 | P28347 | 100.0 | 4e-166 |
X-RAY |
2010-02-23 | VAL | A:81 | A:273 | 2.0 | 0.013 | E | -116.3 | 126.2 | 2.0 | 0.013 | 0.0 |
HOH |
7.535 |
O |
O |
||
| VAL | C:81 | C:273 | 0.0 | 0.0 | E | -116.8 | 125.7 | NA | NA | NA | |||||||||||||
| 6im5 | 1 | P28347 | 99.55 | 3e-165 |
X-RAY |
2019-02-06 | VAL | A:95 | A:288 | 0.0 | 0.0 | E | -116.5 | 121.9 | 0.0 | 0.0 | 0.0 |
PO4 HOH |
9.517 5.887 |
CG1 O |
O4 O |
||
| VAL | B:95 | B:288 | 0.0 | 0.0 | E | -113.9 | 124.7 | NA | NA | NA | |||||||||||||
| 6hil | 1 | P28347 | 99.54 | 4e-165 |
X-RAY |
2019-04-03 | VAL | A:81 | A:273 | 0.0 | 0.0 | E | -112.1 | 123.8 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.924 7.263 |
O O |
C8 O |
||
| VAL | C:81 | D:273 | 0.0 | 0.0 | E | -115.6 | 125.5 | NA | NA | NA | |||||||||||||
| VAL | E:81 | B:273 | 0.0 | 0.0 | E | -115.6 | 123.6 | NA | NA | NA | |||||||||||||
| VAL | G:81 | C:273 | 0.0 | 0.0 | E | -114.1 | 128.7 | NA | NA | NA | |||||||||||||
| 7li5 | 1 | E9PKB7 | 100.0 | 5e-164 |
X-RAY |
2022-02-02 | VAL | A:84 | A:288 | 0.0 | 0.0 | E | -116.4 | 123.7 | 0.0 | 0.0 | 0.0 |
Y2D SO4 HOH |
5.510 9.236 7.192 |
CG2 CG1 CG1 |
H13 O4 O |
||
| VAL | B:84 | B:288 | 1.0 | 0.006 | E | -115.0 | 127.0 | NA | NA | NA | |||||||||||||
| 6ge3 | 1 | Q15561 | 81.74 | 5e-136 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -112.8 | 124.4 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.535 6.873 |
CG1 CG1 |
C8 O |
||
| 6gec | 1 | Q15561 | 81.74 | 5e-136 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -112.6 | 122.8 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.785 7.039 |
CG1 CG1 |
C8 O |
||
| 4ln0 | 1 | Q62296 | 82.19 | 5e-136 |
X-RAY |
2014-02-26 | VAL | A:84 | A:289 | 0.0 | 0.0 | E | -108.5 | 125.8 | 0.0 | 0.0 | 0.0 |
PEG GOL HOH |
9.649 9.465 9.371 |
CG1 CG1 CA |
C4 O2 O |
||
| VAL | B:84 | B:289 | 0.0 | 0.0 | E | -110.5 | 126.5 | 0.0 | 0.0 | 0.0 |
GOL |
6.811 |
O |
C3 |
|||||||||
| 6l9f | 1 | Q62296 | 82.19 | 5e-136 |
X-RAY |
2019-12-11 | VAL | A:84 | A:289 | 0.0 | 0.0 | E | -114.4 | 127.7 | 0.0 | 0.0 | 0.0 |
ACT HOH |
7.145 7.205 |
CG1 O |
O O |
||
| VAL | C:84 | B:289 | 0.0 | 0.0 | E | -105.8 | 128.1 | NA | NA | NA | |||||||||||||
| 6sba | 1 | Q62296 | 82.19 | 1e-135 |
X-RAY |
2020-09-30 | VAL | A:83 | A:289 | 0.0 | 0.0 | E | -113.8 | 127.2 | 0.0 | 0.0 | 0.0 |
GOL GOL HOH |
6.755 7.070 6.522 |
C O HG11 |
H2 H32 O |
||
| 6ge5 | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -108.4 | 126.7 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.766 7.035 |
CG1 CG1 |
C8 O |
||
| 6geg | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -113.5 | 126.7 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.929 7.085 |
CG1 CG1 |
C8 O |
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| 6gek | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -114.5 | 126.4 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.936 7.139 |
CG1 CG1 |
C8 O |
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| VAL | C:81 | B:296 | 0.0 | 0.0 | E | -107.8 | 124.2 | NA | NA | NA | |||||||||||||
| 3jua | 1 | Q62296 | 82.11 | 4e-135 |
X-RAY |
2010-02-23 | VAL | A:82 | A:289 | 4.0 | 0.026 | E | -107.1 | 133.2 | 4.0 | 0.026 | 0.0 |
HOH |
7.038 |
CG1 |
O |
||
| VAL | C:82 | C:289 | 4.0 | 0.026 | E | -107.5 | 128.4 | NA | NA | NA | |||||||||||||
| VAL | E:82 | E:289 | 0.0 | 0.0 | E | -116.2 | 128.7 | NA | NA | NA | |||||||||||||
| VAL | G:82 | G:289 | 0.0 | 0.0 | E | -118.2 | 128.3 | NA | NA | NA | |||||||||||||
| 5xjd | 1 | Q62296 | 82.11 | 4e-135 |
X-RAY |
2018-01-24 | VAL | A:82 | A:289 | 0.0 | 0.0 | E | -114.6 | 125.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.088 |
CG1 |
O |
||
| VAL | B:82 | B:289 | 0.0 | 0.0 | E | -113.5 | 126.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.370 |
O |
O |
|||||||||
| 6ge4 | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -113.9 | 125.0 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.796 7.030 |
CG1 CG1 |
C8 O |
||
| 6gee | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -112.9 | 122.8 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.575 7.118 |
CG1 CG1 |
C8 O |
||
| 6hik | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2019-04-03 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -112.0 | 124.4 | 0.0 | 0.0 | 0.0 |
MYR PO4 HOH |
9.848 9.519 7.247 |
CG1 CG1 CG1 |
C8 O3 O |
||
| 5gn0 | 1 | Q62296 | 82.11 | 6e-135 |
X-RAY |
2017-05-31 | VAL | A:87 | A:289 | 0.0 | 0.0 | E | -125.4 | 136.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.650 |
CG1 |
O |
||
| VAL | B:87 | B:289 | 0.0 | 0.0 | E | -119.3 | 125.8 | NA | NA | NA | |||||||||||||
| VAL | C:87 | C:289 | 0.0 | 0.0 | E | -121.2 | 127.0 | NA | NA | NA | |||||||||||||
| VAL | D:87 | D:289 | 0.0 | 0.0 | E | -120.3 | 129.8 | NA | NA | NA | |||||||||||||
| 5oaq | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2017-10-11 | VAL | A:82 | A:296 | 0.0 | 0.0 | E | -110.4 | 123.8 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.607 6.910 |
CG1 CG1 |
C8 O |
||
| 6q2x | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2019-07-03 | VAL | A:82 | A:296 | 0.0 | 0.0 | E | -109.4 | 122.3 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.778 7.045 |
CG1 CG1 |
C8 O |
||
| 6q36 | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2019-07-03 | VAL | A:82 | A:296 | 0.0 | 0.0 | E | -110.0 | 128.2 | 0.0 | 0.0 | 0.0 |
MYR HOH |
9.987 7.314 |
CG1 CG1 |
C10 O |
||
| VAL | B:82 | B:296 | 0.0 | 0.0 | E | -113.6 | 123.3 | 0.0 | 0.0 | 0.0 |
MYR PO4 HOH |
9.734 9.268 7.125 |
CG1 CG1 CG1 |
C10 O3 O |
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| 5z2q | 4 | Q62296 | 82.49 | 1e-134 |
X-RAY |
2018-01-31 | VAL | D:91 | B:289 | 0.0 | 0.0 | E | -114.8 | 125.3 | 0.0 | 0.0 | 0.0 |
PO4 |
9.476 |
CG1 |
O1 |
||
| 5z2q | 3 | Q62296 | 82.49 | 1e-134 |
X-RAY |
2018-01-31 | VAL | C:89 | A:289 | 0.0 | 0.0 | E | -113.3 | 123.2 | NA | NA | NA | ||||||
| 6ge6 | 1 | Q15561 | 80.82 | 2e-134 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -113.2 | 123.5 | 0.0 | 0.0 | 0.0 |
MYR PO4 HOH |
9.783 9.426 7.136 |
CG1 CG1 CG1 |
C8 O3 O |
||
| 6gei | 1 | Q15561 | 80.82 | 2e-134 |
X-RAY |
2018-09-19 | VAL | A:81 | A:296 | 0.0 | 0.0 | E | -111.6 | 122.9 | 0.0 | 0.0 | 0.0 |
MYR PO4 HOH |
9.611 9.402 7.194 |
CG1 CG1 CG1 |
C7 O3 O |
||
| 6sen | 1 | Q15561 | 81.19 | 4e-134 |
X-RAY |
2019-11-20 | VAL | A:82 | A:296 | 0.0 | 0.0 | E | -107.6 | 126.2 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
9.264 6.981 |
CG1 CG1 |
O4 O |
||
| VAL | B:82 | B:296 | 0.0 | 0.0 | E | -111.3 | 129.0 | NA | NA | NA | |||||||||||||
| 6seo | 1 | Q15561 | 81.19 | 4e-134 |
X-RAY |
2019-11-20 | VAL | A:82 | A:296 | 0.0 | 0.0 | E | -109.1 | 118.3 | 0.0 | 0.0 | 0.0 |
HOH |
9.150 |
CA |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p28347-f1 | 1 | P28347 | 100.0 | 0.0 | VAL | A:288 | A:288 | 0.0 | 0.0 | E | -116.2 | 118.3 | |