Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 12951761 . G A CCDS7810.2:NM_021961.5:c.1055cGa>cAa_NP_068780.2:p.352R>Q Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7cmm 1 P28347 99.55 1e-167 X-RAY
 2021-02-03 ARG A:156 A:352 60.0 0.267 E -116.1 124.3 60.0 0.267 0.0 HOH
 9.325
 C
 O
ARG B:156 B:352 95.0 0.422 E -125.6 125.4 NA NA NA
ARG C:156 C:352 90.0 0.4 E -117.9 124.1 NA NA NA
ARG D:156 D:352 110.0 0.489 E -123.1 120.6 NA NA NA
4re1 1 P28347 99.54 3e-166 X-RAY
 2014-11-19 ARG A:146 A:337 97.0 0.431 E -121.6 132.1 97.0 0.431 0.0 HOH
 3.285
 N
 O
ARG B:146 B:337 87.0 0.387 E -121.7 133.6 NA NA NA
3kys 1 P28347 100.0 4e-166 X-RAY
 2010-02-23 ARG A:145 A:337 104.0 0.462 E -128.5 130.7 104.0 0.462 0.0 HOH
 6.149
 NE
 O
ARG C:145 C:337 92.0 0.409 E -109.9 113.8 NA NA NA
6im5 1 P28347 99.55 3e-165 X-RAY
 2019-02-06 ARG A:159 A:352 112.0 0.498 E -113.3 133.6 112.0 0.498 0.0 HOH
 3.034
 N
 O
ARG B:159 B:352 103.0 0.458 E -116.1 122.2 NA NA NA
6hil 1 P28347 99.54 4e-165 X-RAY
 2019-04-03 ARG A:145 A:337 99.0 0.44 E -139.6 117.2 99.0 0.44 0.0 HOH
 3.049
 O
 O
ARG C:145 D:337 120.0 0.533 E -117.4 123.4 NA NA NA
ARG E:145 B:337 98.0 0.436 E -117.4 128.0 NA NA NA
ARG G:145 C:337 89.0 0.396 E -131.8 113.8 NA NA NA
7li5 1 E9PKB7 100.0 5e-164 X-RAY
 2022-02-02 ARG A:148 A:352 98.0 0.436 E -106.6 127.7 98.0 0.436 0.0 HOH
 2.790
 O
 O
ARG B:148 B:352 82.0 0.364 E -118.0 122.3 NA NA NA
6ge3 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 ARG A:145 A:360 89.0 0.396 E -136.4 130.4 89.0 0.396 0.0 HOH
 2.968
 N
 O
6gec 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 ARG A:145 A:360 83.0 0.369 E -132.8 129.3 83.0 0.369 0.0 HOH
 2.665
 NH1
 O
4ln0 1 Q62296 82.19 5e-136 X-RAY
 2014-02-26 ARG A:148 A:353 110.0 0.489 E -133.4 126.0 108.0 0.48 0.009 C:Q80V24:0.009
 HOH
 9.284
 NH1
 O
ARG B:148 B:353 93.0 NA E -134.0 125.5 93.0 NA NA
6l9f 1 Q62296 82.19 5e-136 X-RAY
 2019-12-11 ARG A:148 A:353 47.0 NA E -150.8 135.8 47.0 NA NA ACT
HOH
 3.445
2.894
 CB
N
 OXT
O
ARG C:148 B:353 39.0 NA E -135.7 137.6 NA NA NA
6sba 1 Q62296 82.19 1e-135 X-RAY
 2020-09-30 ARG A:147 A:353 86.0 0.382 E -136.1 136.4 86.0 0.382 0.0 HOH
 2.816
 O
 O
6ge5 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 ARG A:145 A:360 115.0 0.511 E -130.1 129.9 115.0 0.511 0.0 HOH
 2.788
 NH2
 O
6geg 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 ARG A:145 A:360 105.0 0.467 E -129.7 126.9 105.0 0.467 0.0 HOH
 3.092
 O
 O
6gek 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 ARG A:145 A:360 108.0 0.48 E -144.4 126.9 108.0 0.48 0.0 HOH
 2.728
 NH1
 O
ARG C:145 B:360 117.0 0.52 E -123.8 131.1 NA NA NA
3jua 1 Q62296 82.11 4e-135 X-RAY
 2010-02-23 ARG A:146 A:353 121.0 0.538 E -115.3 122.3 121.0 0.538 0.0 HOH
 3.085
 CD
 O
ARG C:146 C:353 116.0 0.516 E -164.4 136.8 NA NA NA
ARG E:146 E:353 125.0 0.556 E -157.5 147.4 NA NA NA
ARG G:146 G:353 122.0 0.542 E -153.5 134.0 NA NA NA
5xjd 1 Q62296 82.11 4e-135 X-RAY
 2018-01-24 ARG A:146 A:353 144.0 0.64 E -136.7 129.6 144.0 0.64 0.0 HOH
 2.880
 NE
 O
ARG B:146 B:353 137.0 0.609 E -130.0 126.7 137.0 0.609 0.0 HOH
 2.891
 NH2
 O
6ge4 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 ARG A:145 A:360 115.0 0.511 E -132.4 125.4 115.0 0.511 0.0 HOH
 2.779
 NE
 O
6gee 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 ARG A:145 A:360 82.0 0.364 E -132.6 128.2 82.0 0.364 0.0 HOH
 2.667
 NH1
 O
6hik 1 Q15561 81.28 4e-135 X-RAY
 2019-04-03 ARG A:145 A:360 100.0 0.444 E -137.1 132.3 100.0 0.444 0.0 PO4
HOH
 2.909
2.816
 NH1
NH2
 O4
O
5gn0 1 Q62296 82.11 6e-135 X-RAY
 2017-05-31 ARG A:151 A:353 146.0 0.649 E -165.5 156.0 146.0 0.649 0.0
ARG B:151 B:353 140.0 0.622 E -156.2 162.0 NA NA NA
ARG C:151 C:353 143.0 0.636 E -148.8 140.9 NA NA NA
ARG D:151 D:353 147.0 0.653 E -158.8 161.4 NA NA NA
5oaq 1 Q15561 81.65 7e-135 X-RAY
 2017-10-11 ARG A:146 A:360 92.0 0.409 E -132.8 131.1 92.0 0.409 0.0 HOH
 2.982
 N
 O
6q2x 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 ARG A:146 A:360 93.0 0.413 E -134.5 127.9 93.0 0.413 0.0 HOH
 2.987
 N
 O
6q36 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 ARG A:146 A:360 116.0 0.516 E -136.1 138.8 50.0 0.222 0.294 B:Q15561:0.293
 PO4
PO4
PO4
HOH
 3.252
3.612
6.736
2.947
 NE
NH1
NH1
N
 O3
O2
O2
O
ARG B:146 B:360 118.0 0.524 E -138.0 130.9 43.0 0.191 0.333 A:Q15561:0.333
 PO4
PO4
PO4
HOH
 3.634
5.814
5.282
2.769
 CD
NH1
NH1
O
 O1
O3
O4
O
5z2q 4 Q62296 82.49 1e-134 X-RAY
 2018-01-31 ARG D:155 B:353 109.0 0.484 E -127.4 111.1 109.0 0.484 0.0 HOH
 4.826
 NH1
 O
5z2q 3 Q62296 82.49 1e-134 X-RAY
 2018-01-31 ARG C:153 A:353 128.0 0.569 E -128.8 108.4 NA NA NA
6ge6 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 ARG A:145 A:360 111.0 0.493 E -140.7 130.2 111.0 0.493 0.0 PO4
PO4
PO4
HOH
 2.682
4.104
6.241
2.825
 NE
NH1
CD
N
 O3
O3
O3
O
6gei 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 ARG A:145 A:360 106.0 0.471 E -133.2 126.2 106.0 0.471 0.0 HOH
 2.953
 NE
 O
6sen 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 ARG A:146 A:360 123.0 0.547 E -148.2 137.8 123.0 0.547 0.0 SO4
HOH
 2.773
2.694
 NE
O
 O4
O
ARG B:146 B:360 107.0 0.476 E -139.4 134.8 NA NA NA
6seo 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 ARG A:146 A:360 97.0 0.431 E -119.7 114.7 97.0 0.431 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28347-f1 1 P28347 100.0 0.0 ARG A:352 A:352 58.0 0.258 E -135.3 114.3