Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 12951778 . A C CCDS7810.2:NM_021961.5:c.1072Atg>Ctg_NP_068780.2:p.358M>L Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7cmm 1 P28347 99.55 1e-167 X-RAY
 2021-02-03 MET A:162 A:358 31.0 0.168 -70.0 146.4 31.0 0.168 0.0 KK9
HOH
 3.559
8.152
 CE
CA
 C6
O
MET B:162 B:358 30.0 0.162 -68.2 150.1 NA NA NA
MET C:162 C:358 32.0 0.173 -70.1 144.0 NA NA NA
MET D:162 D:358 32.0 0.173 -69.7 150.8 NA NA NA
4re1 1 P28347 99.54 3e-166 X-RAY
 2014-11-19 MET A:152 A:343 25.0 0.135 -65.1 136.6 25.0 0.135 0.0 HOH
 4.919
 O
 O
MET B:152 B:343 25.0 0.135 -63.6 143.1 NA NA NA
3kys 1 P28347 100.0 4e-166 X-RAY
 2010-02-23 MET A:151 A:343 10.0 0.054 -79.3 155.0 10.0 0.054 0.0 HOH
 8.458
 O
 O
MET C:151 C:343 9.0 0.049 -65.9 147.0 NA NA NA
6im5 1 P28347 99.55 3e-165 X-RAY
 2019-02-06 MET A:165 A:358 25.0 0.135 -67.2 148.8 25.0 0.135 0.0 HOH
 2.776
 O
 O
MET B:165 B:358 22.0 0.119 -68.5 145.9 NA NA NA
6hil 1 P28347 99.54 4e-165 X-RAY
 2019-04-03 MET A:151 A:343 20.0 0.108 -68.7 134.7 20.0 0.108 0.0 MYR
HOH
 3.436
5.469
 CA
O
 O2
O
MET C:151 D:343 22.0 0.119 -63.8 137.2 NA NA NA
MET E:151 B:343 23.0 0.124 -57.8 147.4 NA NA NA
MET G:151 C:343 24.0 0.13 -77.8 136.9 NA NA NA
7li5 1 E9PKB7 100.0 5e-164 X-RAY
 2022-02-02 MET A:154 A:358 25.0 0.135 -60.1 152.4 25.0 0.135 0.0 Y2D
HOH
 3.198
3.605
 CA
O
 O2
O
MET B:154 B:358 24.0 0.13 -68.5 152.1 NA NA NA
6ge3 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 LEU A:151 A:366 22.0 0.129 -68.5 134.4 22.0 0.129 0.0 MYR
HOH
 3.404
2.945
 CD1
O
 O1
O
6gec 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 LEU A:151 A:366 22.0 0.129 -67.1 133.0 22.0 0.129 0.0 MYR
HOH
 3.905
2.791
 CD1
O
 C7
O
4ln0 1 Q62296 82.19 5e-136 X-RAY
 2014-02-26 LEU A:154 A:359 31.0 0.182 -65.9 144.7 31.0 0.182 0.0 PEG
HOH
 3.914
4.743
 CD1
CA
 C2
O
LEU B:154 B:359 28.0 0.165 -63.5 145.6 28.0 0.165 0.0 PEG
 4.076
 CD1
 C3
6l9f 1 Q62296 82.19 5e-136 X-RAY
 2019-12-11 LEU A:154 A:359 8.0 0.047 -63.2 128.9 8.0 0.047 0.0 HOH
 3.298
 O
 O
LEU C:154 B:359 12.0 0.071 -63.8 153.9 NA NA NA
6sba 1 Q62296 82.19 1e-135 X-RAY
 2020-09-30 LEU A:153 A:359 5.0 0.029 -65.4 144.9 5.0 0.029 0.0 GOL
HOH
 8.789
3.932
 O
H
 HO1
O
6ge5 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 LEU A:151 A:366 19.0 0.112 -68.4 131.0 19.0 0.112 0.0 MYR
HOH
 3.797
3.400
 CD1
O
 C5
O
6geg 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 LEU A:151 A:366 21.0 0.124 -66.9 135.5 21.0 0.124 0.0 MYR
HOH
 3.797
3.125
 CD1
O
 C7
O
6gek 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 LEU A:151 A:366 23.0 0.135 -70.0 127.4 23.0 0.135 0.0 MYR
HOH
 3.735
4.857
 CD1
O
 C7
O
LEU C:151 B:366 26.0 0.153 -70.0 128.6 NA NA NA
3jua 1 Q62296 82.11 4e-135 X-RAY
 2010-02-23 LEU A:152 A:359 31.0 0.182 -101.7 130.0 31.0 0.182 0.0 HOH
 5.963
 CA
 O
LEU C:152 C:359 32.0 0.188 -65.5 126.3 NA NA NA
LEU E:152 E:359 35.0 0.206 -61.1 133.5 NA NA NA
LEU G:152 G:359 91.0 0.535 S -61.9 -40.1 NA NA NA
5xjd 1 Q62296 82.11 4e-135 X-RAY
 2018-01-24 LEU A:152 A:359 25.0 0.147 -65.7 134.4 25.0 0.147 0.0 HOH
 2.621
 O
 O
LEU B:152 B:359 22.0 0.129 -66.3 135.1 22.0 0.129 0.0 HOH
 3.914
 CD1
 O
6ge4 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 LEU A:151 A:366 27.0 0.159 -69.4 131.6 27.0 0.159 0.0 MYR
HOH
 3.799
4.992
 CD1
O
 C7
O
6gee 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 LEU A:151 A:366 22.0 0.129 -68.4 132.6 22.0 0.129 0.0 MYR
HOH
 3.780
2.729
 C
O
 O1
O
6hik 1 Q15561 81.28 4e-135 X-RAY
 2019-04-03 LEU A:151 A:366 24.0 0.141 -66.0 134.0 24.0 0.141 0.0 MYR
HOH
 3.775
2.986
 CD1
O
 C7
O
5gn0 1 Q62296 82.11 6e-135 X-RAY
 2017-05-31 LEU A:157 A:359 34.0 0.2 -65.6 136.9 34.0 0.2 0.0
LEU B:157 B:359 28.0 0.165 -64.6 142.6 NA NA NA
LEU C:157 C:359 40.0 0.235 -81.1 152.0 NA NA NA
LEU D:157 D:359 27.0 0.159 -68.3 143.7 NA NA NA
5oaq 1 Q15561 81.65 7e-135 X-RAY
 2017-10-11 LEU A:152 A:366 22.0 0.129 -68.3 135.5 22.0 0.129 0.0 MYR
HOH
 3.801
3.278
 CD1
O
 C5
O
6q2x 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 LEU A:152 A:366 21.0 0.124 -69.1 134.5 21.0 0.124 0.0 MYR
HOH
 3.751
3.414
 CD1
O
 C4
O
6q36 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 LEU A:152 A:366 25.0 0.147 -64.0 131.7 25.0 0.147 0.0 MYR
HOH
 3.684
3.183
 CD1
O
 C7
O
LEU B:152 B:366 28.0 0.165 -67.6 136.9 28.0 0.165 0.0 MYR
HOH
 3.829
3.695
 CD1
CA
 C7
O
5z2q 4 Q62296 82.49 1e-134 X-RAY
 2018-01-31 LEU D:161 B:359 28.0 0.165 -81.4 136.0 28.0 0.165 0.0
5z2q 3 Q62296 82.49 1e-134 X-RAY
 2018-01-31 LEU C:159 A:359 28.0 0.165 -79.1 137.8 NA NA NA
6ge6 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 LEU A:151 A:366 27.0 0.159 -65.9 135.2 27.0 0.159 0.0 MYR
HOH
 3.856
2.906
 CD1
O
 C7
O
6gei 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 LEU A:151 A:366 19.0 0.112 -65.6 135.0 19.0 0.112 0.0 HOH
 2.725
 O
 O
6sen 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 LEU A:152 A:366 6.0 0.035 -67.7 140.1 6.0 0.035 0.0 HOH
 3.037
 O
 O
LEU B:152 B:366 9.0 0.053 -67.6 142.5 NA NA NA
6seo 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 LEU A:152 A:366 7.0 0.041 -69.2 140.0 7.0 0.041 0.0 HOH
 4.173
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28347-f1 1 P28347 100.0 0.0 MET A:358 A:358 23.0 0.124 -66.2 145.1