Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 12951854 . A C CCDS7810.2:NM_021961.5:c.1148gAa>gCa_NP_068780.2:p.383E>A Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7cmm 1 P28347 99.55 1e-167 X-RAY
 2021-02-03 GLU A:187 A:383 125.0 0.658 G -63.3 -29.1 125.0 0.658 0.0 KK9
 9.620
 N
 CL1
GLU B:187 B:383 123.0 0.647 T -57.2 -37.8 NA NA NA
GLU C:187 C:383 121.0 0.637 T -66.2 -28.5 NA NA NA
GLU D:187 D:383 110.0 0.579 T -55.3 -39.1 NA NA NA
4re1 1 P28347 99.54 3e-166 X-RAY
 2014-11-19 GLU A:177 A:368 112.0 0.589 T -52.8 -31.2 40.0 0.211 0.378 D:P46937:0.379
 HOH
 5.159
 OE2
 O
GLU B:177 B:368 122.0 0.642 T -53.0 -32.9 NA NA NA
3kys 1 P28347 100.0 4e-166 X-RAY
 2010-02-23 GLU A:176 A:368 120.0 0.632 T -53.1 -42.0 54.0 0.284 0.348 B:P46937:0.347
 HOH
 4.639
 O
 O
GLU C:176 C:368 113.0 0.595 G -53.0 -37.7 NA NA NA
6im5 1 P28347 99.55 3e-165 X-RAY
 2019-02-06 GLU A:190 A:383 122.0 0.642 T -57.0 -24.1 122.0 0.642 0.0 HOH
 2.313
 OE2
 O
GLU B:190 B:383 95.0 0.5 T -59.7 -25.7 NA NA NA
6hil 1 P28347 99.54 4e-165 X-RAY
 2019-04-03 GLU A:176 A:368 121.0 0.637 T -60.5 -26.4 37.0 0.195 0.442 B:P46937:0.442
 MYR
HOH
 9.159
2.670
 N
O
 C14
O
GLU C:176 D:368 123.0 0.647 T -61.9 -24.9 NA NA NA
GLU E:176 B:368 129.0 0.679 T -53.1 -29.0 NA NA NA
GLU G:176 C:368 123.0 0.647 T -41.0 -39.5 NA NA NA
7li5 1 E9PKB7 100.0 5e-164 X-RAY
 2022-02-02 GLU A:179 A:383 117.0 0.616 T -56.7 -29.8 117.0 0.616 0.0 Y2D
HOH
 9.459
2.444
 N
OE1
 F2
O
GLU B:179 B:383 130.0 0.684 T -61.3 -28.0 NA NA NA
6ge3 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 GLU A:176 A:391 116.0 0.611 T -53.2 -35.9 41.0 0.216 0.395 B:P46937:0.395
 MYR
GOL
HOH
 9.085
5.384
2.502
 N
O
OE1
 C14
O3
O
6gec 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 GLU A:176 A:391 120.0 0.632 T -52.1 -35.2 35.0 0.184 0.448 B:P46937:0.447
 MYR
HOH
 9.363
2.626
 N
OE1
 C14
O
4ln0 1 Q62296 82.19 5e-136 X-RAY
 2014-02-26 GLU A:179 A:384 116.0 0.611 H -44.4 -41.5 116.0 0.611 0.0 HOH
 5.803
 O
 O
GLU B:179 B:384 125.0 0.658 T -45.0 -44.5 125.0 0.658 0.0 GOL
 6.805
 O
 O3
6l9f 1 Q62296 82.19 5e-136 X-RAY
 2019-12-11 GLU A:179 A:384 134.0 0.705 T -64.8 -24.3 65.0 0.342 0.363 B:Q8N9Y4:0.363
 HOH
 2.691
 OE2
 O
GLU C:179 B:384 121.0 0.637 H -58.1 -34.8 NA NA NA
6sba 1 Q62296 82.19 1e-135 X-RAY
 2020-09-30 GLU A:178 A:384 110.0 0.579 H -57.2 -30.0 110.0 0.579 0.0 GOL
GOL
HOH
 7.267
1.926
2.280
 O
HA
OE2
 HO1
H31
O
6ge5 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 GLU A:176 A:391 122.0 0.642 T -54.7 -30.7 44.0 0.232 0.41 B:P46937:0.411
 MYR
HOH
 9.378
2.331
 N
OE1
 C14
O
6geg 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 GLU A:176 A:391 124.0 0.653 T -54.3 -37.3 45.0 0.237 0.416 B:P46937:0.416
 MYR
HOH
 9.518
2.310
 N
OE1
 C14
O
6gek 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 GLU A:176 A:391 132.0 0.695 T -55.2 -28.0 47.0 0.247 0.448 B:P46937:0.447
 MYR
HOH
 9.719
3.053
 N
CG
 C14
O
GLU C:176 B:391 128.0 0.674 T -54.5 -30.2 NA NA NA
3jua 1 Q62296 82.11 4e-135 X-RAY
 2010-02-23 GLU A:177 A:384 102.0 0.537 T -35.7 -42.4 33.0 0.174 0.363 B:P46938:0.363
 HOH
 2.348
 O
 O
GLU C:177 C:384 136.0 0.716 H -53.4 -34.8 NA NA NA
GLU E:177 E:384 125.0 0.658 T -46.0 -29.5 NA NA NA
GLU G:177 G:384 112.0 0.589 T -63.5 -29.8 NA NA NA
5xjd 1 Q62296 82.11 4e-135 X-RAY
 2018-01-24 GLU A:177 A:384 116.0 0.611 T -56.5 -27.4 96.0 0.505 0.106 B:Q62296:0.105
 87L
HOH
 9.062
3.653
 N
N
 CAI
O
GLU B:177 B:384 122.0 0.642 T -59.0 -23.9 122.0 0.642 0.0 87L
HOH
 9.439
3.141
 N
OE1
 CAD
O
6ge4 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 GLU A:176 A:391 126.0 0.663 T -50.0 -33.4 41.0 0.216 0.447 B:P46937:0.447
 MYR
HOH
 9.404
2.622
 N
OE1
 C14
O
6gee 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 GLU A:176 A:391 126.0 0.663 T -54.4 -30.0 38.0 0.2 0.463 B:P46937:0.463
 MYR
HOH
 9.286
2.512
 N
OE1
 C14
O
6hik 1 Q15561 81.28 4e-135 X-RAY
 2019-04-03 GLU A:176 A:391 125.0 0.658 T -62.2 -24.4 50.0 0.263 0.395 B:P46937:0.395
 MYR
HOH
 9.173
2.786
 N
OE1
 C14
O
5gn0 1 Q62296 82.11 6e-135 X-RAY
 2017-05-31 GLU A:182 A:384 147.0 0.774 T -63.6 -33.2 76.0 0.4 0.374 E:Q9EPK5:0.374
GLU B:182 B:384 122.0 0.642 G -63.0 -40.2 NA NA NA
GLU C:182 C:384 140.0 0.737 G -67.3 -25.6 NA NA NA
GLU D:182 D:384 135.0 0.711 G -66.8 -28.8 NA NA NA
5oaq 1 Q15561 81.65 7e-135 X-RAY
 2017-10-11 GLU A:177 A:391 123.0 0.647 T -53.0 -34.9 42.0 0.221 0.426 B:P46937:0.426
 GOL
MYR
HOH
 5.603
9.554
2.386
 O
N
OE1
 O3
C14
O
6q2x 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 GLU A:177 A:391 127.0 0.668 T -50.1 -34.2 41.0 0.216 0.452 B:P46937:0.453
 GOL
MYR
HOH
 5.634
9.863
2.424
 O
N
OE1
 O3
C14
O
6q36 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 GLU A:177 A:391 124.0 0.653 T -61.5 -21.7 84.0 0.442 0.211 C:None:0.211
 HOH
 2.644
 OE1
 O
GLU B:177 B:391 136.0 0.716 T -65.5 -14.3 93.0 0.489 0.227 D:None:0.226
 MYR
HOH
 9.967
2.726
 N
O
 C14
O
5z2q 4 Q62296 82.49 1e-134 X-RAY
 2018-01-31 GLU D:186 B:384 116.0 0.611 H -62.4 -30.2 116.0 0.611 0.0
5z2q 3 Q62296 82.49 1e-134 X-RAY
 2018-01-31 GLU C:184 A:384 115.0 0.605 H -56.7 -34.3 NA NA NA
6ge6 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 GLU A:176 A:391 124.0 0.653 T -48.0 -36.9 36.0 0.189 0.464 B:P46937:0.463
 MYR
HOH
 9.291
2.535
 N
OE2
 C14
O
6gei 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 GLU A:176 A:391 125.0 0.658 T -63.4 -22.9 38.0 0.2 0.458 B:P46937:0.458
 MYR
HOH
 8.665
2.286
 N
OE1
 C14
O
6sen 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 GLU A:177 A:391 128.0 0.674 T -61.0 -25.3 58.0 0.305 0.369 C:Q8N9Y4:0.368
 HOH
 2.715
 OE2
 O
GLU B:177 B:391 120.0 0.632 T -59.2 -25.2 NA NA NA
6seo 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 GLU A:177 A:391 133.0 0.7 G -87.2 1.5 63.0 0.332 0.368 B:A6NEQ2:0.368
 HOH
 7.391
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28347-f1 1 P28347 100.0 0.0 GLU A:383 A:383 114.0 0.6 T -54.3 -34.4