Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 61094352 | . | C | A | CCDS31576.1:NM_001923.4:c.563cGg>cTg_NP_001914.3:p.188R>L | Homo sapiens damage specific DNA binding protein 1 (DDB1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3e0c | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2008-09-16 | ARG | A:188 | A:188 | 62.0 | 0.276 | 360.0 | 140.1 | 62.0 | 0.276 | 0.0 |
HOH |
6.214 |
NH1 |
O |
|||
| 5hxb | 2 | Q16531 | 100.0 | 0.0 |
X-RAY |
2016-06-29 | ARG | B:188 | Y:188 | 33.0 | 0.147 | E | -114.1 | 136.3 | 7.0 | 0.031 | 0.116 |
C:Q96SW2:0.116 |
|||||
| ARG | D:188 | B:188 | 12.0 | NA | E | -113.6 | 129.3 | NA | NA | NA | |||||||||||||
| 5jk7 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | ARG | A:188 | A:188 | 28.0 | NA | E | -81.9 | 142.4 | 28.0 | NA | NA | ||||||
| ARG | B:188 | B:188 | 26.0 | NA | E | -81.6 | 142.5 | NA | NA | NA | |||||||||||||
| 5v3o | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2017-05-03 | ARG | A:188 | A:188 | 40.0 | 0.178 | E | -106.8 | 119.7 | 7.0 | 0.031 | 0.147 |
B:Q96SW2:0.147 |
|||||
| 6dsz | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-12-12 | ARG | A:188 | A:188 | 33.0 | 0.147 | E | -128.6 | 156.9 | 33.0 | 0.147 | 0.0 | ||||||
| ARG | B:188 | B:188 | 33.0 | 0.147 | E | -124.7 | 157.3 | NA | NA | NA | |||||||||||||
| 6pai | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-09-18 | ARG | A:188 | A:188 | 32.0 | 0.142 | E | -101.9 | 151.0 | 32.0 | 0.142 | 0.0 | ||||||
| 6sj7 | 2 | Q16531 | 100.0 | 0.0 |
EM |
2019-12-18 | ARG | B:188 | B:188 | 43.0 | NA | 360.0 | 152.3 | 43.0 | NA | NA | |||||||
| 6uml | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2020-04-15 | ARG | A:188 | A:188 | 41.0 | 0.182 | E | -114.7 | 150.7 | 13.0 | 0.058 | 0.124 |
B:Q96SW2:0.124 |
|||||
| 6xk9 | 2 | Q16531 | 100.0 | 0.0 |
X-RAY |
2020-12-02 | ARG | B:188 | Y:188 | 42.0 | 0.187 | E | -104.8 | 137.6 | 10.0 | 0.044 | 0.143 |
C:Q96SW2:0.142 |
|||||
| ARG | E:188 | B:188 | 50.0 | 0.222 | E | -104.1 | 135.2 | NA | NA | NA | |||||||||||||
| 7lps | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2021-06-02 | ARG | A:188 | A:188 | 44.0 | 0.196 | E | -94.8 | 137.3 | 2.0 | 0.009 | 0.187 |
B:Q96SW2:0.187 |
|||||
| ARG | D:188 | D:188 | 43.0 | 0.191 | E | -94.5 | 137.3 | NA | NA | NA | |||||||||||||
| ARG | G:188 | G:188 | 45.0 | 0.2 | E | -94.7 | 137.6 | NA | NA | NA | |||||||||||||
| ARG | J:188 | J:188 | 43.0 | 0.191 | E | -94.6 | 137.5 | NA | NA | NA | |||||||||||||
| 7oop | 26 | Q16531 | 100.0 | 0.0 |
EM |
2021-10-06 | ARG | Z:188 | d:188 | 27.0 | 0.12 | E | -104.4 | 138.8 | 27.0 | 0.12 | 0.0 | ||||||
| 6zue | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2021-07-28 | ARG | A:190 | A:188 | 21.0 | 0.093 | E | -106.2 | 158.3 | 21.0 | 0.093 | 0.0 | ||||||
| 6zx9 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2021-07-21 | ARG | A:190 | A:188 | 21.0 | 0.093 | E | -131.2 | 153.9 | 21.0 | 0.093 | 0.0 |
HOH |
3.909 |
NH2 |
O |
||
| 7oo3 | 20 | Q16531 | 100.0 | 0.0 |
EM |
2021-10-06 | ARG | T:191 | d:188 | 34.0 | 0.151 | E | -104.9 | 136.7 | 34.0 | 0.151 | 0.0 | ||||||
| 7oob | 14 | Q16531 | 100.0 | 0.0 |
EM |
2021-10-13 | ARG | N:191 | d:188 | 30.0 | 0.133 | E | -103.5 | 137.2 | 30.0 | 0.133 | 0.0 | ||||||
| 7opc | 26 | Q16531 | 100.0 | 0.0 |
EM |
2021-10-13 | ARG | Z:191 | d:188 | 32.0 | 0.142 | E | -104.6 | 137.6 | 32.0 | 0.142 | 0.0 | ||||||
| 7opd | 26 | Q16531 | 100.0 | 0.0 |
EM |
2021-10-06 | ARG | Z:191 | d:188 | 32.0 | 0.142 | E | -104.4 | 137.6 | 32.0 | 0.142 | 0.0 | ||||||
| 4a0l | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2011-12-14 | ARG | A:192 | A:188 | 26.0 | 0.116 | E | -117.7 | 153.7 | 26.0 | 0.116 | 0.0 | ||||||
| ARG | C:192 | C:188 | 24.0 | 0.107 | E | -118.1 | 153.6 | NA | NA | NA | |||||||||||||
| 6r8y | 8 | Q16531 | 100.0 | 0.0 |
EM |
2019-06-12 | ARG | K:192 | K:188 | 34.0 | 0.151 | E | -105.4 | 139.7 | 34.0 | 0.151 | 0.0 | ||||||
| 6r8z | 7 | Q16531 | 100.0 | 0.0 |
EM |
2019-06-12 | ARG | K:211 | K:188 | 47.0 | 0.209 | E | -100.9 | 146.8 | 47.0 | 0.209 | 0.0 | ||||||
| 6r90 | 7 | Q16531 | 100.0 | 0.0 |
EM |
2019-06-12 | ARG | K:211 | K:188 | 53.0 | 0.236 | E | -103.4 | 140.6 | 53.0 | 0.236 | 0.0 | ||||||
| 6r91 | 7 | Q16531 | 100.0 | 0.0 |
EM |
2019-06-12 | ARG | K:211 | K:188 | 55.0 | 0.244 | E | -104.3 | 147.3 | 55.0 | 0.244 | 0.0 | ||||||
| 6r92 | 8 | Q16531 | 100.0 | 0.0 |
EM |
2019-06-12 | ARG | L:211 | K:188 | 53.0 | 0.236 | E | -103.6 | 147.5 | 53.0 | 0.236 | 0.0 | ||||||
| 4a0k | 3 | Q16531 | 100.0 | 0.0 |
X-RAY |
2011-12-14 | ARG | C:207 | C:188 | 35.0 | 0.156 | E | -108.8 | 171.2 | 35.0 | 0.156 | 0.0 | ||||||
| 4a11 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2011-12-07 | ARG | A:207 | A:188 | 42.0 | 0.187 | E | -101.9 | 142.9 | 42.0 | 0.187 | 0.0 | ||||||
| 7okq | 1 | Q16531 | 100.0 | 0.0 |
EM |
2021-10-13 | ARG | A:207 | A:188 | 26.0 | NA | E | -88.5 | 134.4 | 26.0 | NA | NA | ||||||
| ARG | E:207 | E:188 | 25.0 | NA | E | -88.6 | 134.4 | NA | NA | NA | |||||||||||||
| ARG | I:207 | I:188 | 25.0 | NA | E | -88.5 | 134.4 | NA | NA | NA | |||||||||||||
| ARG | M:207 | M:188 | 26.0 | NA | E | -88.5 | 134.4 | NA | NA | NA | |||||||||||||
| 3ei1 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2009-01-20 | ARG | A:206 | A:188 | 25.0 | 0.111 | E | -132.0 | 152.5 | 25.0 | 0.111 | 0.0 |
HOH |
3.452 |
NH1 |
O |
||
| 3ei2 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2009-01-20 | ARG | A:206 | A:188 | 24.0 | 0.107 | E | -117.9 | 153.7 | 24.0 | 0.107 | 0.0 |
HOH |
3.443 |
NH1 |
O |
||
| 3ei3 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2009-01-20 | ARG | A:206 | A:188 | 29.0 | 0.129 | E | -112.7 | 147.6 | 29.0 | 0.129 | 0.0 |
HOH |
3.023 |
N |
O |
||
| 4ci1 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:206 | A:188 | 43.0 | 0.191 | E | -113.3 | 117.6 | 19.0 | 0.084 | 0.107 |
B:P0CF65:0.107 |
|||||
| 4ci2 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:206 | A:188 | 43.0 | 0.191 | E | -113.3 | 116.7 | 18.0 | 0.08 | 0.111 |
B:P0CF65:0.111 |
|||||
| 4ci3 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2014-07-16 | ARG | A:206 | A:188 | 43.0 | 0.191 | E | -115.4 | 118.1 | 17.0 | 0.076 | 0.115 |
B:P0CF65:0.116 |
|||||
| 6fcv | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-01-30 | ARG | A:206 | A:188 | 29.0 | 0.129 | E | -106.7 | 135.0 | 29.0 | 0.129 | 0.0 | ||||||
| 4tz4 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2014-08-06 | ARG | A:187 | A:188 | 33.0 | 0.147 | E | -114.4 | 138.0 | 4.0 | 0.018 | 0.129 |
B:Q96SW2:0.129 |
|||||
| 3i7h | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 35.0 | 0.156 | E | -118.9 | 144.5 | 35.0 | 0.156 | 0.0 | ||||||
| 3i7k | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 33.0 | 0.147 | E | -106.8 | 160.2 | 33.0 | 0.147 | 0.0 | ||||||
| 3i7l | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 23.0 | 0.102 | E | -116.9 | 152.9 | 23.0 | 0.102 | 0.0 | ||||||
| 3i7n | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 26.0 | 0.116 | E | -110.9 | 157.0 | 26.0 | 0.116 | 0.0 | ||||||
| 3i7o | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 33.0 | 0.147 | E | -129.0 | 144.9 | 33.0 | 0.147 | 0.0 | ||||||
| 3i7p | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 30.0 | 0.133 | E | -97.5 | 165.3 | 30.0 | 0.133 | 0.0 | ||||||
| 3i89 | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 25.0 | 0.111 | E | -114.9 | 149.2 | 25.0 | 0.111 | 0.0 | ||||||
| 3i8c | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 36.0 | 0.16 | E | -123.5 | 153.6 | 36.0 | 0.16 | 0.0 | ||||||
| 3i8e | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-12-08 | ARG | A:191 | A:188 | 38.0 | 0.169 | E | -96.3 | 138.9 | 38.0 | 0.169 | 0.0 | ||||||
| ARG | B:191 | B:188 | 30.0 | 0.133 | -72.1 | 138.5 | NA | NA | NA | ||||||||||||||
| 2b5l | 1 | 13435359 | 99.74 | 0.0 |
X-RAY |
2006-02-28 | ARG | A:188 | A:188 | 36.0 | 0.16 | E | -109.6 | 131.7 | 36.0 | 0.16 | 0.0 | ||||||
| ARG | B:188 | B:188 | 51.0 | 0.227 | E | -95.8 | 121.1 | NA | NA | NA | |||||||||||||
| 2b5m | 1 | 13435359 | 99.74 | 0.0 |
X-RAY |
2006-02-28 | ARG | A:188 | A:188 | 31.0 | 0.138 | E | -118.6 | 157.8 | 31.0 | 0.138 | 0.0 | ||||||
| 2hye | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2006-10-03 | ARG | A:188 | A:188 | 41.0 | 0.182 | E | -100.5 | 104.8 | 41.0 | 0.182 | 0.0 | ||||||
| 4a0b | 1 | Q16531 | 99.91 | 0.0 |
X-RAY |
2011-11-30 | ARG | A:207 | A:188 | 33.0 | 0.147 | E | -125.7 | 140.4 | 33.0 | 0.147 | 0.0 | ||||||
| ARG | C:207 | C:188 | 27.0 | 0.12 | E | -117.2 | 144.3 | NA | NA | NA | |||||||||||||
| 4a0a | 1 | Q16531 | 99.91 | 0.0 |
X-RAY |
2011-11-30 | ARG | A:207 | A:188 | 36.0 | 0.16 | E | -111.9 | 133.8 | 36.0 | 0.16 | 0.0 | ||||||
| 4a08 | 1 | Q16531 | 99.91 | 0.0 |
X-RAY |
2011-11-30 | ARG | A:207 | A:188 | 29.0 | 0.129 | E | -146.3 | 153.1 | 29.0 | 0.129 | 0.0 | ||||||
| 4a09 | 1 | Q16531 | 99.91 | 0.0 |
X-RAY |
2011-11-30 | ARG | A:207 | A:188 | 28.0 | 0.124 | E | -123.9 | 151.5 | 28.0 | 0.124 | 0.0 | ||||||
| 4e54 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2012-08-08 | ARG | A:198 | A:188 | 27.0 | 0.12 | E | -117.7 | 153.6 | 25.0 | 0.111 | 0.009 |
B:Q92466:0.009 |
|||||
| 4e5z | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2012-08-22 | ARG | A:198 | A:188 | 32.0 | 0.142 | E | -97.2 | 155.0 | 32.0 | 0.142 | 0.0 | ||||||
| 3ei4 | 1 | Q16531 | 99.74 | 0.0 |
X-RAY |
2009-01-20 | ARG | A:206 | A:188 | 45.0 | 0.2 | E | -118.5 | 138.6 | 41.0 | 0.182 | 0.018 |
B:Q92466:0.018 |
|||||
| ARG | C:206 | C:188 | 44.0 | 0.196 | E | -119.5 | 138.5 | NA | NA | NA | |||||||||||||
| ARG | E:206 | E:188 | 44.0 | 0.196 | E | -119.4 | 138.3 | NA | NA | NA | |||||||||||||
| 6ud7 | 2 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-12-18 | ARG | B:188 | B:188 | 27.0 | 0.12 | E | -102.9 | 146.5 | 27.0 | 0.12 | 0.0 |
HOH |
2.835 |
NH1 |
O |
||
| 6ue5 | 2 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-12-18 | ARG | B:188 | B:188 | 28.0 | 0.124 | E | -113.3 | 140.8 | 28.0 | 0.124 | 0.0 |
HOH |
2.839 |
N |
O |
||
| 6td3 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2020-06-17 | ARG | A:192 | A:188 | 46.0 | 0.204 | E | -103.7 | 145.5 | 46.0 | 0.204 | 0.0 | ||||||
| ARG | D:192 | D:188 | 46.0 | 0.204 | E | -103.4 | 145.4 | NA | NA | NA | |||||||||||||
| ARG | G:192 | G:188 | 49.0 | 0.218 | E | -103.8 | 145.6 | NA | NA | NA | |||||||||||||
| 5fqd | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2016-02-24 | ARG | A:208 | A:188 | 37.0 | 0.164 | E | -95.4 | 133.4 | 2.0 | 0.009 | 0.155 |
B:Q96SW2:0.156 |
|||||
| ARG | D:208 | D:188 | 35.0 | 0.156 | E | -94.7 | 132.8 | NA | NA | NA | |||||||||||||
| 6h0f | 1 | ? | 100.0 | 0.0 |
X-RAY |
2018-11-07 | ARG | A:208 | A:188 | 39.0 | 0.173 | E | -95.9 | 144.4 | 4.0 | 0.018 | 0.155 |
B:Q96SW2:0.156 |
|||||
| ARG | D:208 | D:188 | 41.0 | 0.182 | E | -96.0 | 144.6 | NA | NA | NA | |||||||||||||
| ARG | G:208 | G:188 | 42.0 | 0.187 | E | -96.1 | 137.5 | NA | NA | NA | |||||||||||||
| ARG | J:208 | J:188 | 40.0 | 0.178 | E | -96.0 | 144.4 | NA | NA | NA | |||||||||||||
| 6h0g | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-11-07 | ARG | A:208 | A:188 | 42.0 | 0.187 | E | -95.6 | 138.0 | 4.0 | 0.018 | 0.169 |
B:Q96SW2:0.169 |
|||||
| ARG | D:208 | D:188 | 41.0 | 0.182 | E | -95.5 | 138.2 | NA | NA | NA | |||||||||||||
| 6bn7 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-05-30 | ARG | A:216 | A:188 | 38.0 | 0.169 | E | -99.4 | 136.7 | 5.0 | 0.022 | 0.147 |
B:Q96SW2:0.147 |
|||||
| 6bn8 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | ARG | A:216 | A:188 | 46.0 | 0.204 | E | -95.6 | 136.9 | 4.0 | 0.018 | 0.186 |
B:Q96SW2:0.187 |
|||||
| 6bn9 | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-05-30 | ARG | A:216 | A:188 | 43.0 | 0.191 | E | -107.3 | 133.1 | 6.0 | 0.027 | 0.164 |
B:Q96SW2:0.164 |
|||||
| 6bnb | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-05-30 | ARG | A:216 | A:188 | 33.0 | 0.147 | E | -138.2 | 126.0 | 6.0 | 0.027 | 0.12 |
B:Q96SW2:0.12 |
|||||
| 6boy | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2018-05-30 | ARG | A:216 | A:188 | 39.0 | 0.173 | E | -103.4 | 134.5 | 4.0 | 0.018 | 0.155 |
B:Q96SW2:0.156 |
|||||
| 6q0r | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-11-13 | ARG | A:216 | A:188 | 28.0 | 0.124 | E | -103.1 | 143.3 | 28.0 | 0.124 | 0.0 |
HOH |
8.738 |
NH2 |
O |
||
| 6q0v | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-11-13 | ARG | A:216 | A:188 | 30.0 | 0.133 | E | -108.3 | 143.4 | 30.0 | 0.133 | 0.0 |
HOH |
8.753 |
CA |
O |
||
| 6q0w | 1 | Q16531 | 100.0 | 0.0 |
X-RAY |
2019-11-13 | ARG | A:216 | A:188 | 30.0 | 0.133 | E | -105.3 | 145.3 | 30.0 | 0.133 | 0.0 |
HOH |
9.603 |
NH2 |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q16531-f1 | 1 | Q16531 | 100.0 | 0.0 | ARG | A:188 | A:188 | 45.0 | 0.2 | E | -95.1 | 142.7 | |