Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 67169219 . A C CCDS8160.1:NM_002708.3:c.35aTc>aGc_NP_002699.1:p.12I>S Homo sapiens protein phosphatase 1 catalytic subunit alpha (PPP1CA), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1fjm 1 P08129 100.0 0.0 X-RAY
1996-06-20 ILE A:12 A:12 0.0 0.0 H -57.0 -50.5 0.0 0.0 0.0 HOH
6.365
C
O
ILE B:12 B:12 0.0 0.0 H -58.1 -55.3 NA NA NA
4g9j 1 P62136 100.0 0.0 X-RAY
2012-09-19 ILE A:13 A:12 11.0 0.063 H -69.4 -43.7 11.0 0.063 0.0 HOH
7.798
O
O
ILE B:13 B:12 1.0 0.006 H -54.6 -62.2 NA NA NA
6g0i 1 P62136 100.0 0.0 X-RAY
2018-11-21 ILE A:13 A:12 7.0 0.04 H -56.0 -49.6 7.0 0.04 0.0 HOH
5.507
N
O
6g0j 1 P62136 100.0 0.0 X-RAY
2018-11-21 ILE A:13 A:12 8.0 0.046 H -60.4 -43.5 8.0 0.046 0.0 HOH
5.765
CD1
O
5zqv 1 P62137 99.7 0.0 X-RAY
2019-03-13 ILE A:12 A:12 2.0 0.011 H -66.7 -45.7 2.0 0.011 0.0
ILE B:12 B:12 2.0 0.011 H -72.9 -52.2 NA NA NA
ILE C:12 C:12 0.0 0.0 H -74.4 -52.9 0.0 0.0 0.0
ILE D:12 D:12 1.0 0.006 H -64.1 -49.4 NA NA NA
6dcx 1 P62136 100.0 0.0 X-RAY
2019-05-15 ILE A:21 A:12 6.0 0.034 H -64.8 -50.3 6.0 0.034 0.0
ILE B:21 B:12 7.0 0.04 H -65.6 -49.7 NA NA NA
6zk6 1 P62136 99.7 0.0 X-RAY
2020-11-18 ILE A:13 A:12 10.0 0.057 H -59.2 -49.3 10.0 0.057 0.0 HOH
7.573
O
O
3egg 1 P62136 100.0 0.0 X-RAY
2010-03-23 ILE A:11 A:12 0.0 0.0 H -62.3 -50.7 0.0 0.0 0.0 HOH
3.535
CD1
O
ILE B:11 B:12 0.0 0.0 H -61.9 -51.9 NA NA NA
3egh 1 P62136 100.0 0.0 X-RAY
2010-03-23 ILE A:11 A:12 0.0 0.0 H -61.6 -52.2 0.0 0.0 0.0 HOH
3.595
CD1
O
ILE B:11 B:12 0.0 0.0 H -66.3 -48.3 NA NA NA
3hvq 1 P62136 100.0 0.0 X-RAY
2010-03-23 ILE A:11 A:12 0.0 0.0 H -60.4 -49.8 0.0 0.0 0.0 HOH
3.570
CD1
O
ILE B:11 B:12 0.0 0.0 H -57.5 -48.9 0.0 0.0 0.0 GOL
HOH
6.883
4.832
O
N
C3
O
6ghm 1 P62136 100.0 0.0 X-RAY
2019-02-27 ILE A:11 A:12 0.0 0.0 H -59.6 -53.0 0.0 0.0 0.0 EDO
HOH
7.022
4.060
N
CD1
O2
O
ILE B:11 B:12 6.0 0.034 H -62.4 -49.8 NA NA NA
3v4y 1 P62136 100.0 0.0 X-RAY
2012-10-31 ILE A:11 A:12 0.0 0.0 H -59.3 -46.6 0.0 0.0 0.0 HOH
3.936
HG13
O
ILE C:11 C:12 0.0 0.0 H -59.6 -51.7 NA NA NA
ILE E:11 E:12 1.0 0.006 H -65.4 -53.9 NA NA NA
ILE G:11 G:12 1.0 0.006 H -55.6 -49.4 NA NA NA
3n5u 1 P62136 100.0 0.0 X-RAY
2010-08-11 ILE A:12 A:12 0.0 0.0 H -58.4 -56.4 0.0 0.0 0.0
ILE B:12 B:12 0.0 0.0 H -58.0 -56.7 0.0 0.0 0.0
6obn 1 P62136 100.0 0.0 X-RAY
2019-09-18 ILE A:17 A:12 8.0 0.046 H -70.1 -46.5 8.0 0.046 0.0 MPD
HOH
3.747
6.901
CD1
CA
O4
O
ILE B:17 B:12 0.0 0.0 H -69.4 -45.0 NA NA NA
6obp 1 P62136 100.0 0.0 X-RAY
2019-09-18 ILE A:17 A:12 2.0 0.011 H -65.0 -45.7 2.0 0.011 0.0 HOH
5.097
CD1
O
6zej 1 P62136,Q4VY12 100.0 0.0 X-RAY
2020-09-30 ILE A:11 D:11 2.0 0.011 H -61.8 -49.1 2.0 0.011 0.0 HOH
4.444
H
O
ILE B:11 A:11 0.0 0.0 H -65.3 -47.9 NA NA NA
ILE C:11 F:11 0.0 0.0 H -63.3 -48.8 NA NA NA
ILE D:11 I:11 3.0 0.017 H -61.6 -51.9 NA NA NA
ILE E:11 L:11 0.0 0.0 H -62.3 -53.2 NA NA NA
ILE F:11 O:11 0.0 0.0 H -67.9 -45.5 NA NA NA
6zeh 1 P62136,Q13813 100.0 0.0 X-RAY
2020-09-30 ILE A:11 A:12 0.0 0.0 H -58.3 -49.3 0.0 0.0 0.0 HOH
4.825
HD11
O
ILE C:11 B:12 0.0 0.0 H -58.4 -49.3 NA NA NA
1it6 1 P36873 90.66 0.0 X-RAY
2002-05-22 ILE A:12 A:12 0.0 0.0 H -64.8 -49.8 0.0 0.0 0.0 HOH
5.854
N
O
ILE B:12 B:12 0.0 0.0 H -68.7 -41.2 NA NA NA
1jk7 1 P36873 90.66 0.0 X-RAY
2001-08-15 ILE A:12 A:12 0.0 0.0 H -61.2 -51.3 0.0 0.0 0.0 HOH
4.615
CD1
O
2bcd 1 P36873 90.66 0.0 X-RAY
2006-01-17 ILE A:12 A:12 0.0 0.0 H -66.5 -50.5 0.0 0.0 0.0 HOH
6.445
C
O
2bdx 1 P36873 90.66 0.0 X-RAY
2006-01-17 ILE A:12 A:12 0.0 0.0 H -62.2 -47.3 0.0 0.0 0.0 HOH
3.275
CB
O
4ut2 1 P36873 90.66 0.0 X-RAY
2015-07-22 ILE A:12 A:12 0.0 0.0 H -60.9 -48.4 0.0 0.0 0.0 HOH
6.807
O
O
ILE B:12 B:12 0.0 0.0 H -61.0 -48.2 NA NA NA
4ut3 1 P36873 90.66 0.0 X-RAY
2015-07-22 ILE A:12 A:12 0.0 0.0 H -61.2 -43.9 0.0 0.0 0.0 HOH
7.187
O
O
4ut3 2 P36873 90.66 0.0 X-RAY
2015-07-22 ILE B:12 B:12 0.0 0.0 H -60.8 -44.2 NA NA NA
4v0u 2 P63087 90.66 0.0 X-RAY
2015-03-25 ILE D:12 D:12 1.0 0.006 H -61.8 -47.6 NA NA NA
ILE F:12 F:12 1.0 0.006 H -61.8 -47.6 NA NA NA
ILE H:12 H:12 1.0 0.006 H -62.0 -47.5 NA NA NA
ILE J:12 J:12 1.0 0.006 H -61.9 -47.6 1.0 0.006 0.0
ILE N:12 N:12 1.0 0.006 H -61.8 -47.5 NA NA NA
2o8a 1 P63088 90.63 0.0 X-RAY
2007-07-17 ILE A:18 A:12 0.0 0.0 H -61.0 -49.0 0.0 0.0 0.0 HOH
6.121
C
O
ILE C:18 B:12 0.0 0.0 H -54.7 -52.9 NA NA NA
2o8g 1 P63088 90.63 0.0 X-RAY
2007-07-17 ILE A:18 A:12 0.0 0.0 H -62.0 -51.4 0.0 0.0 0.0 HOH
6.630
N
O
ILE C:18 B:12 0.0 0.0 H -55.0 -53.9 NA NA NA
6zeg 1 P62136,Q9UQB8 100.0 0.0 X-RAY
2020-09-30 ILE A:11 A:12 0.0 0.0 H -56.1 -50.5 0.0 0.0 0.0 HOH
3.272
HD11
O
ILE C:11 B:12 0.0 0.0 H -60.3 -49.7 NA NA NA
6zei 1 P62136,Q9UQB8 100.0 0.0 X-RAY
2020-09-30 ILE A:11 A:12 0.0 0.0 H -60.0 -47.8 0.0 0.0 0.0 HOH
3.964
HD11
O
ILE C:11 B:12 0.0 0.0 H -57.9 -48.9 NA NA NA
3e7a 1 P62136 99.66 0.0 X-RAY
2008-11-04 ILE A:11 A:12 0.0 0.0 H -62.6 -50.7 0.0 0.0 0.0 HOH
3.993
CD1
O
ILE B:11 B:12 0.0 0.0 H -57.2 -51.3 NA NA NA
3e7b 1 P62136 99.66 0.0 X-RAY
2008-11-04 ILE A:11 A:12 0.0 0.0 H -61.7 -51.7 0.0 0.0 0.0 HOH
4.571
CG1
O
ILE B:11 B:12 0.0 0.0 H -58.5 -52.5 NA NA NA
4mov 1 P62136 99.66 0.0 X-RAY
2014-03-26 ILE A:11 A:12 0.0 0.0 H -61.2 -49.0 0.0 0.0 0.0 HOH
4.071
CD1
O
ILE B:11 B:12 0.0 0.0 H -59.9 -50.1 NA NA NA
4moy 1 P62136 99.66 0.0 X-RAY
2014-03-26 ILE A:11 A:12 0.0 0.0 H -57.3 -50.2 0.0 0.0 0.0 HOH
6.142
C
O
4mp0 1 P62136 99.66 0.0 X-RAY
2014-03-26 ILE A:11 A:12 0.0 0.0 H -62.3 -51.0 0.0 0.0 0.0 HOH
4.608
CG1
O
ILE B:11 C:12 0.0 0.0 H -62.4 -50.7 NA NA NA
4xpn 1 P62136 99.66 0.0 X-RAY
2015-07-01 ILE A:11 A:12 0.0 0.0 H -59.4 -47.4 0.0 0.0 0.0 HOH
5.038
N
O
ILE C:11 C:12 0.0 0.0 H -58.8 -47.5 NA NA NA
5ioh 1 P62136 99.66 0.0 X-RAY
2016-10-05 ILE A:11 A:12 1.0 0.006 H -65.9 -49.4 1.0 0.006 0.0 HOH
7.680
CG2
O
ILE C:11 C:12 6.0 0.034 H -65.6 -50.0 NA NA NA
6alz 1 P62136 99.66 0.0 X-RAY
2017-11-29 ILE A:11 A:12 0.0 0.0 H -65.0 -46.3 0.0 0.0 0.0 HOH
6.347
N
O
ILE B:11 B:12 0.0 0.0 H -66.5 -51.0 NA NA NA
6czo 1 P62136 99.66 0.0 X-RAY
2019-01-23 ILE A:11 A:12 0.0 0.0 H -60.8 -52.7 0.0 0.0 0.0 HOH
7.261
N
O
ILE C:11 C:12 0.0 0.0 H -63.3 -50.8 NA NA NA
6dno 1 P62136 99.66 0.0 X-RAY
2019-01-23 ILE A:11 A:12 0.0 0.0 H -63.1 -49.1 0.0 0.0 0.0 HOH
5.842
C
O
6zee 1 P62136 99.66 0.0 X-RAY
2020-09-30 ILE A:11 P:12 0.0 0.0 H -64.3 -50.6 0.0 0.0 0.0 EDO
EDO
SO4
HOH
6.069
7.788
9.983
5.465
HG23
C
O
N
H22
H11
O2
O
ILE B:11 Q:12 0.0 0.0 H -69.6 -49.9 0.0 0.0 0.0 EDO
HOH
9.858
4.605
O
H
HO2
O
ILE C:11 B:12 0.0 0.0 H -66.4 -48.9 0.0 0.0 0.0 EDO
EDO
HOH
7.746
5.652
4.655
C
HG23
H
H12
H21
O
ILE D:11 A:12 0.0 0.0 H -63.4 -45.2 0.0 0.0 0.0 EDO
EDO
EDO
HOH
7.810
6.198
5.899
4.454
C
HD11
HG23
H
H21
HO2
H22
O
ILE E:11 I:12 0.0 0.0 H -62.4 -54.3 0.0 0.0 0.0 EDO
EDO
HOH
9.452
5.631
6.510
HA
HG23
N
H22
H11
O
ILE F:11 K:12 0.0 0.0 H -62.1 -54.5 0.0 0.0 0.0 EDO
HOH
5.327
4.621
N
H
H22
O
6zef 1 P62136 99.66 0.0 X-RAY
2020-09-30 ILE A:11 A:12 0.0 0.0 H -63.0 -47.0 0.0 0.0 0.0 EDO
HOH
7.826
4.548
C
H
H22
O
ILE B:11 B:12 1.0 0.006 H -63.3 -48.3 NA NA NA
5zt0 1 P62137 99.66 0.0 X-RAY
2019-03-13 ILE A:6 A:12 2.0 0.011 H -63.0 -52.2 2.0 0.011 0.0
ILE B:6 B:12 3.0 0.017 H -60.3 -50.1 NA NA NA
ILE C:6 C:12 1.0 0.006 H -65.8 -50.7 NA NA NA
ILE D:6 D:12 2.0 0.011 H -63.8 -49.3 NA NA NA
ILE E:6 E:12 2.0 0.011 H -66.8 -51.5 NA NA NA
ILE F:6 F:12 2.0 0.011 H -65.4 -49.5 NA NA NA
7nzm 2 P62139 99.66 0.0 EM
2021-09-29 ILE B:6 B:12 17.0 0.097 H -62.7 -48.8 17.0 0.097 0.0
6obq 1 P62136 99.66 0.0 X-RAY
2019-09-18 ILE A:11 A:12 0.0 0.0 H -62.1 -47.9 0.0 0.0 0.0 HOH
5.758
N
O
ILE B:11 B:12 0.0 0.0 H -61.0 -48.4 NA NA NA
6obr 1 P62136 99.32 0.0 X-RAY
2019-09-18 ILE A:11 A:12 0.0 0.0 H -61.7 -50.4 0.0 0.0 0.0 HOH
4.854
N
O
ILE B:11 B:12 0.0 0.0 H -61.0 -49.8 NA NA NA
6obs 1 P62136 99.66 0.0 X-RAY
2019-09-18 ILE A:11 A:12 0.0 0.0 H -63.4 -48.9 0.0 0.0 0.0 HOH
4.971
CG1
O
ILE B:11 B:12 0.0 0.0 H -61.9 -48.4 NA NA NA
6obu 1 P62136 99.66 0.0 X-RAY
2019-09-18 ILE A:11 A:12 0.0 0.0 H -60.3 -48.7 0.0 0.0 0.0 DMS
HOH
9.287
5.829
N
N
C1
O
ILE B:11 B:12 0.0 0.0 H -60.5 -50.6 NA NA NA
1s70 1 P62140 88.79 0.0 X-RAY
2004-06-22 LEU A:14 A:12 2.0 0.012 H -72.2 -53.5 2.0 0.012 0.0 HOH
5.583
N
O
5inb 1 P36873 97.31 0.0 X-RAY
2016-10-05 ILE A:9 A:12 0.0 0.0 H -61.5 -46.7 0.0 0.0 0.0 HOH
4.031
CD1
O
5j28 1 P36873 97.31 0.0 X-RAY
2016-10-05 ILE A:9 A:12 0.0 0.0 H -65.0 -45.9 0.0 0.0 0.0 HOH
6.217
C
O
ILE B:9 B:12 0.0 0.0 H -56.5 -44.8 NA NA NA
4v0v 1 P63087 97.62 0.0 X-RAY
2015-03-25 ILE A:7 A:12 1.0 0.006 H -62.6 -46.7 1.0 0.006 0.0 HOH
3.923
CD1
O
ILE C:7 C:12 0.0 0.0 H -61.5 -45.4 NA NA NA
4v0w 1 P63087 97.62 0.0 X-RAY
2015-03-25 ILE A:7 A:12 1.0 0.006 H -64.8 -46.1 1.0 0.006 0.0 HOH
3.812
CD1
O
ILE C:7 C:12 0.0 0.0 H -67.4 -44.4 NA NA NA
4v0x 1 P63087 97.62 0.0 X-RAY
2015-03-25 ILE A:7 A:12 0.0 0.0 H -58.3 -46.6 0.0 0.0 0.0 HOH
7.206
C
O
1u32 1 P36873 96.25 0.0 X-RAY
2004-08-17 ILE A:7 A:12 0.0 0.0 H -62.8 -47.3 0.0 0.0 0.0 HOH
5.343
N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62136-f1 1 P62136 100.0 0.0 ILE A:12 A:12 0.0 0.0 H -65.6 -50.2
af-p36873-f1 1 P36873 90.66 0.0 ILE A:12 A:12 1.0 0.006 H -66.6 -49.9
af-p62140-f1 1 P62140 88.79 0.0 LEU A:11 A:11 0.0 0.0 H -70.6 -43.3