Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 85967534 | . | A | C | CCDS8273.1:NM_003797.3:c.532Ata>Cta_NP_003788.2:p.178I>L | Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6c23 | 4 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | ILE | D:178 | L:178 | 103.0 | 0.589 | T | -53.1 | -54.7 | 66.0 | 0.377 | 0.212 |
K:Q15910:0.211 |
|||||
| 6c24 | 5 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | ILE | E:178 | L:178 | 101.0 | 0.577 | T | -76.5 | -60.6 | 52.0 | 0.297 | 0.28 |
L:Q15910:0.28 |
|||||
| 6wkr | 3 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ILE | C:178 | L:178 | 100.0 | 0.571 | T | -59.0 | -36.7 | 63.0 | 0.36 | 0.211 |
E:Q15910:0.211 |
|||||
| 7kso | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ILE | B:178 | B:178 | 97.0 | 0.554 | T | -68.7 | -52.2 | 47.0 | 0.269 | 0.285 |
A:Q92800:0.286 |
|||||
| 7ksr | 4 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ILE | D:178 | B:178 | 101.0 | 0.577 | T | -69.7 | -51.6 | 53.0 | 0.303 | 0.274 |
A:Q92800:0.274 |
|||||
| 7ktp | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ILE | B:178 | B:178 | 98.0 | 0.56 | T | -68.5 | -53.3 | 39.0 | 0.223 | 0.337 |
A:Q92800:0.337 |
|||||
| 5wg6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2018-06-27 | ILE | B:179 | B:178 | 78.0 | 0.446 | T | -103.2 | -61.3 | 43.0 | 0.246 | 0.2 |
A:Q15910+Q15022:0.2 |
|||||
| ILE | D:179 | D:178 | 97.0 | 0.554 | T | -72.0 | -42.2 | NA | NA | NA | |||||||||||||
| 3jpx | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-10-20 | ILE | A:139 | A:178 | 123.0 | 0.703 | T | -68.7 | -57.1 | 123.0 | 0.703 | 0.0 |
HOH |
2.373 |
O |
O |
||
| 3jzg | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ILE | A:139 | A:178 | 129.0 | 0.737 | T | -66.5 | -56.3 | 129.0 | 0.737 | 0.0 |
HOH |
3.124 |
O |
O |
||
| 3jzh | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ILE | A:139 | A:178 | 121.0 | 0.691 | T | -70.5 | -53.8 | 121.0 | 0.691 | 0.0 |
HOH |
2.934 |
CD1 |
O |
||
| 7kxt | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ILE | A:139 | A:178 | 77.0 | NA | T | -78.0 | -47.0 | 77.0 | NA | NA | ||||||
| ILE | B:139 | B:178 | 102.0 | 0.583 | T | -79.7 | -47.4 | NA | NA | NA | |||||||||||||
| 5wp3 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-09-13 | ILE | A:105 | A:178 | 108.0 | 0.617 | T | -75.7 | -45.3 | 108.0 | 0.617 | 0.0 |
UNX |
4.200 |
CD1 |
UNK |
||
| 5h13 | 1 | O75530 | 99.19 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:113 | A:178 | 105.0 | 0.6 | T | -64.3 | -43.8 | 105.0 | 0.6 | 0.0 |
HOH |
2.953 |
O |
O |
||
| 3jzn | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ILE | A:103 | A:178 | 116.0 | 0.663 | T | -63.9 | -55.2 | 116.0 | 0.663 | 0.0 |
HOH |
2.521 |
O |
O |
||
| 3k26 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ILE | A:103 | A:178 | 123.0 | 0.703 | T | -66.8 | -55.9 | 123.0 | 0.703 | 0.0 |
HOH |
3.185 |
CD1 |
O |
||
| 3k27 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ILE | A:103 | A:178 | 125.0 | 0.714 | T | -68.5 | -51.1 | 125.0 | 0.714 | 0.0 |
HOH |
3.096 |
CD1 |
O |
||
| 6sfb | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | ILE | A:103 | A:178 | 111.0 | 0.634 | T | -71.5 | -44.2 | 111.0 | 0.634 | 0.0 |
HOH |
3.295 |
CD1 |
O |
||
| ILE | B:103 | B:178 | 121.0 | 0.691 | T | -72.3 | -44.5 | NA | NA | NA | |||||||||||||
| 6sfc | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | ILE | A:103 | A:178 | 100.0 | 0.571 | T | -70.1 | -45.4 | 100.0 | 0.571 | 0.0 |
HOH |
3.170 |
CD1 |
O |
||
| ILE | B:103 | B:178 | 112.0 | 0.64 | T | -70.7 | -46.1 | NA | NA | NA | |||||||||||||
| 6yvi | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | ILE | A:103 | A:178 | 102.0 | 0.583 | T | -71.5 | -44.2 | 102.0 | 0.583 | 0.0 |
HOH |
3.287 |
CD1 |
O |
||
| ILE | B:103 | B:178 | 108.0 | 0.617 | T | -60.7 | -57.1 | NA | NA | NA | |||||||||||||
| 6yvj | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | ILE | A:103 | A:178 | 106.0 | 0.606 | T | -74.5 | -46.5 | 106.0 | 0.606 | 0.0 |
HOH |
3.301 |
CD1 |
O |
||
| ILE | B:103 | B:178 | 111.0 | 0.634 | T | -74.8 | -46.7 | NA | NA | NA | |||||||||||||
| 7p3c | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ILE | A:103 | A:178 | 107.0 | 0.611 | T | -74.1 | -41.1 | 107.0 | 0.611 | 0.0 |
HOH |
3.216 |
CD1 |
O |
||
| ILE | B:103 | B:178 | 113.0 | 0.646 | T | -75.0 | -41.8 | NA | NA | NA | |||||||||||||
| 7p3g | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ILE | A:103 | A:178 | 110.0 | 0.629 | T | -77.6 | -46.0 | 110.0 | 0.629 | 0.0 |
HOH |
3.349 |
O |
O |
||
| ILE | B:103 | B:178 | 115.0 | 0.657 | T | -77.7 | -46.9 | NA | NA | NA | |||||||||||||
| 7p3j | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ILE | A:103 | A:178 | 101.0 | 0.577 | T | -72.7 | -46.4 | 101.0 | 0.577 | 0.0 |
HOH |
3.337 |
CD1 |
O |
||
| ILE | B:103 | B:178 | 114.0 | 0.651 | T | -73.3 | -46.6 | NA | NA | NA | |||||||||||||
| 5gsa | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-01 | ILE | A:104 | A:178 | 96.0 | 0.549 | T | -73.0 | -37.8 | 52.0 | 0.297 | 0.252 |
C:Q15910:0.251 |
HOH |
3.597 |
O |
O |
|
| ILE | B:104 | B:178 | 110.0 | 0.629 | T | -85.5 | -46.1 | NA | NA | NA | |||||||||||||
| 5h14 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:104 | A:178 | 104.0 | 0.594 | T | -70.7 | -34.9 | 66.0 | 0.377 | 0.217 |
D:Q15910:0.217 |
HOH |
3.915 |
CA |
O |
|
| ILE | B:104 | B:178 | 98.0 | 0.56 | T | -79.8 | -41.5 | NA | NA | NA | |||||||||||||
| 5h15 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:104 | A:178 | 100.0 | 0.571 | T | -79.4 | -42.5 | 52.0 | 0.297 | 0.274 |
C:Q15910:0.274 |
HOH |
4.183 |
CG2 |
O |
|
| ILE | B:104 | B:178 | 107.0 | 0.611 | T | -68.3 | -40.9 | NA | NA | NA | |||||||||||||
| 5h17 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:104 | A:178 | 99.0 | 0.566 | T | -62.8 | -43.0 | 99.0 | 0.566 | 0.0 |
HOH |
4.894 |
N |
O |
||
| 5h19 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:104 | A:178 | 103.0 | 0.589 | T | -68.7 | -39.7 | 61.0 | 0.349 | 0.24 |
B:Q15910:0.24 |
HOH |
3.398 |
O |
O |
|
| 5h24 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:104 | A:178 | 104.0 | 0.594 | T | -64.8 | -38.6 | 62.0 | 0.354 | 0.24 |
C:Q15910:0.24 |
|||||
| ILE | B:104 | B:178 | 96.0 | 0.549 | T | -82.6 | -42.4 | NA | NA | NA | |||||||||||||
| 5h25 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:104 | A:178 | 98.0 | 0.56 | T | -86.3 | -36.3 | 54.0 | 0.309 | 0.251 |
C:Q15910:0.251 |
|||||
| ILE | B:104 | B:178 | 96.0 | 0.549 | T | -72.7 | -34.1 | NA | NA | NA | |||||||||||||
| 5ttw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ILE | A:104 | A:178 | 101.0 | 0.577 | T | -69.4 | -59.1 | 101.0 | 0.577 | 0.0 |
UNX UNX HOH |
3.311 4.184 4.012 |
CD1 CD1 CD1 |
UNK UNK O |
||
| ILE | C:104 | C:178 | 114.0 | 0.651 | T | -66.0 | -43.0 | NA | NA | NA | |||||||||||||
| 5u5h | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ILE | A:104 | A:178 | 130.0 | 0.743 | T | -71.5 | -40.8 | 130.0 | 0.743 | 0.0 |
HOH |
3.704 |
CD1 |
O |
||
| 5u5k | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ILE | A:104 | A:178 | 119.0 | 0.68 | T | -66.2 | -38.0 | 119.0 | 0.68 | 0.0 |
HOH |
4.076 |
CD1 |
O |
||
| 5u5t | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ILE | A:104 | A:178 | 107.0 | 0.611 | T | -71.4 | -35.8 | 61.0 | 0.349 | 0.262 |
C:Q15910:0.263 |
HOH |
3.110 |
O |
O |
|
| ILE | B:104 | B:178 | 98.0 | 0.56 | T | -76.0 | -34.3 | NA | NA | NA | |||||||||||||
| 5u62 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ILE | A:104 | A:178 | 104.0 | 0.594 | T | -70.0 | -33.7 | 60.0 | 0.343 | 0.251 |
C:Q15910:0.251 |
HOH |
3.194 |
O |
O |
|
| ILE | B:104 | B:178 | 111.0 | 0.634 | T | -70.8 | -32.4 | NA | NA | NA | |||||||||||||
| 6lo2 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-07-07 | ILE | A:104 | A:178 | 106.0 | 0.606 | T | -65.3 | -44.0 | 63.0 | 0.36 | 0.246 |
C:Q15910:0.246 |
HOH |
9.332 |
C |
O |
|
| ILE | B:104 | B:178 | 99.0 | 0.566 | T | -70.2 | -43.6 | NA | NA | NA | |||||||||||||
| 6v3x | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | ILE | A:104 | A:178 | 98.0 | 0.56 | T | -63.7 | -53.1 | 98.0 | 0.56 | 0.0 |
HOH |
2.525 |
O |
O |
||
| 4x3e | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2015-01-21 | ILE | A:104 | A:178 | 98.0 | 0.56 | T | -69.5 | -48.3 | 98.0 | 0.56 | 0.0 |
HOH |
4.811 |
CD1 |
O |
||
| 5hyn | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-11 | ILE | B:104 | B:178 | 100.0 | 0.571 | T | -64.8 | -44.8 | 37.0 | 0.211 | 0.36 |
A:Q15910:0.36 |
|||||
| ILE | G:104 | G:178 | 101.0 | 0.577 | T | -69.2 | -45.5 | NA | NA | NA | |||||||||||||
| ILE | L:104 | L:178 | 98.0 | 0.56 | T | -70.4 | -52.6 | NA | NA | NA | |||||||||||||
| ILE | Q:104 | R:178 | 99.0 | 0.566 | T | -70.2 | -48.6 | NA | NA | NA | |||||||||||||
| 5ls6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-22 | ILE | B:104 | B:178 | 106.0 | 0.606 | T | -96.0 | -40.6 | 37.0 | 0.211 | 0.395 |
A:Q15910:0.394 |
|||||
| ILE | E:104 | E:178 | 104.0 | 0.594 | T | -74.3 | -37.6 | NA | NA | NA | |||||||||||||
| ILE | H:104 | H:178 | 101.0 | 0.577 | T | -65.1 | -57.8 | NA | NA | NA | |||||||||||||
| ILE | K:104 | K:178 | 101.0 | 0.577 | T | -76.8 | -55.0 | NA | NA | NA | |||||||||||||
| 5u69 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ILE | A:106 | A:178 | 127.0 | 0.726 | T | -67.1 | -54.8 | 127.0 | 0.726 | 0.0 |
HOH |
2.440 |
O |
O |
||
| 5u6d | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ILE | A:106 | A:178 | 123.0 | 0.703 | T | -65.6 | -55.8 | 123.0 | 0.703 | 0.0 |
HOH |
2.496 |
O |
O |
||
| 5u8a | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ILE | A:106 | A:178 | 123.0 | 0.703 | T | -65.2 | -56.1 | 123.0 | 0.703 | 0.0 |
HOH |
3.193 |
CD1 |
O |
||
| 5u8f | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ILE | A:106 | A:178 | 122.0 | 0.697 | T | -64.9 | -54.7 | 122.0 | 0.697 | 0.0 |
HOH |
2.418 |
O |
O |
||
| 3iiw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-09-15 | ILE | A:102 | A:178 | 119.0 | 0.68 | T | -66.5 | -51.5 | 119.0 | 0.68 | 0.0 |
HOH |
3.152 |
CD1 |
O |
||
| 5k0m | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ILE | A:109 | A:178 | 109.0 | 0.623 | T | -65.7 | -54.9 | 109.0 | 0.623 | 0.0 |
HOH |
2.542 |
O |
O |
||
| 5wuk | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2017-05-03 | ILE | A:103 | A:178 | 99.0 | 0.566 | T | -83.4 | -47.1 | 46.0 | 0.263 | 0.303 |
B:Q15910:0.303 |
HOH |
3.409 |
O |
O |
|
| 6u4y | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2020-07-08 | ILE | D:103 | D:178 | 90.0 | 0.514 | T | -74.4 | -54.5 | 44.0 | 0.251 | 0.263 |
A:Q15910:0.263 |
|||||
| ILE | E:103 | E:178 | 97.0 | 0.554 | T | -76.0 | -43.2 | 47.0 | 0.269 | 0.285 |
B:Q15910:0.286 |
||||||||||||
| ILE | F:103 | F:178 | 85.0 | 0.486 | T | -77.7 | -46.3 | 43.0 | 0.246 | 0.24 |
C:Q15910:0.24 |
||||||||||||
| 6w7f | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | ILE | A:105 | A:178 | 117.0 | 0.669 | T | -68.6 | -52.8 | 117.0 | 0.669 | 0.0 |
HOH |
2.554 |
O |
O |
||
| 6w7g | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | ILE | A:105 | A:178 | 118.0 | 0.674 | T | -67.4 | -53.4 | 118.0 | 0.674 | 0.0 |
HOH |
2.482 |
O |
O |
||
| 7msb | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | ILE | A:105 | A:178 | 118.0 | 0.674 | T | -68.5 | -51.5 | 118.0 | 0.674 | 0.0 |
HOH |
2.516 |
O |
O |
||
| 7msd | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | ILE | A:105 | A:178 | 114.0 | 0.651 | T | -67.2 | -51.4 | 114.0 | 0.651 | 0.0 |
HOH |
2.575 |
O |
O |
||
| 3iiy | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ILE | A:102 | A:178 | 115.0 | 0.657 | T | -71.9 | -61.4 | 115.0 | 0.657 | 0.0 |
HOH |
2.492 |
O |
O |
||
| 3ij0 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ILE | A:102 | A:178 | 119.0 | 0.68 | T | -65.1 | -56.4 | 119.0 | 0.68 | 0.0 |
HOH |
2.419 |
O |
O |
||
| 3ij1 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ILE | A:102 | A:178 | 125.0 | 0.714 | T | -65.3 | -54.0 | 125.0 | 0.714 | 0.0 |
HOH |
2.529 |
O |
O |
||
| 3ijc | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ILE | A:102 | A:178 | 101.0 | 0.577 | T | -63.4 | -56.5 | 101.0 | 0.577 | 0.0 |
HOH |
5.141 |
CG1 |
O |
||
| 2qxv | 1 | Q921E6 | 100.0 | 0.0 |
X-RAY |
2007-08-28 | ILE | A:98 | A:177 | 105.0 | 0.6 | T | -90.6 | -41.6 | 58.0 | 0.331 | 0.269 |
B:Q61188:0.269 |
HOH |
3.621 |
CG2 |
O |
|
| 4w2r | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | ILE | C:99 | E:164 | 91.0 | 0.52 | T | -73.4 | -26.9 | NA | NA | NA | ||||||
| ILE | D:99 | F:164 | 92.0 | 0.526 | T | -77.0 | -13.7 | 43.0 | 0.246 | 0.28 |
A:G1KPH4:0.28 |
||||||||||||
| 5ij7 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | ILE | C:99 | E:164 | 93.0 | 0.531 | T | -77.0 | -40.8 | 44.0 | 0.251 | 0.28 |
A:G1KPH4+Q15910:0.28 |
HOH |
6.445 |
CD1 |
O |
|
| ILE | D:99 | F:164 | 93.0 | 0.531 | T | -77.6 | -41.0 | NA | NA | NA | |||||||||||||
| 5ij8 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | ILE | C:99 | E:164 | 90.0 | 0.514 | T | -83.4 | -49.2 | NA | NA | NA | ||||||
| ILE | D:99 | F:164 | 93.0 | 0.531 | T | -83.8 | -49.4 | 47.0 | 0.269 | 0.262 |
A:G1KPH4+Q15910:0.263 |
||||||||||||
| 6b3w | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | ILE | C:99 | E:164 | 96.0 | 0.549 | T | -75.4 | -8.4 | NA | NA | NA | ||||||
| ILE | D:99 | F:164 | 99.0 | 0.566 | T | -72.3 | -7.6 | 43.0 | 0.246 | 0.32 |
A:G1KPH4:0.32 |
||||||||||||
| 6v3y | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | ILE | A:98 | A:178 | 118.0 | 0.674 | T | -67.4 | -53.5 | 118.0 | 0.674 | 0.0 |
HOH |
2.428 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o75530-f1 | 1 | O75530 | 100.0 | 0.0 | ILE | A:178 | A:178 | 98.0 | 0.56 | T | -83.2 | -37.5 | |