Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 85975273 | . | G | A | CCDS8273.1:NM_003797.3:c.694Gta>Ata_NP_003788.2:p.232V>I | Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6c23 | 4 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | VAL | D:232 | L:232 | 99.0 | 0.639 | S | -59.1 | -47.7 | 27.0 | 0.174 | 0.465 |
E:Q15022:0.258 C:Q15910:0.213 K:Q15910:0.129 |
|||||
| 6c24 | 5 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | VAL | E:232 | L:232 | 103.0 | 0.665 | T | -62.7 | -40.8 | 28.0 | 0.181 | 0.484 |
D:Q15910:0.284 F:Q15022:0.252 L:Q15910:0.129 |
|||||
| 6wkr | 3 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | VAL | C:232 | L:232 | 105.0 | 0.677 | T | -53.0 | -34.2 | 29.0 | 0.187 | 0.49 |
B:Q15022:0.348 E:Q15910:0.239 |
|||||
| 7kso | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | VAL | B:232 | B:232 | 95.0 | 0.613 | T | -69.4 | -34.4 | 24.0 | 0.155 | 0.458 |
A:Q92800:0.284 C:Q15022:0.258 |
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| 7ksr | 4 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | VAL | D:232 | B:232 | 94.0 | 0.606 | T | -69.7 | -35.0 | 18.0 | 0.116 | 0.49 |
A:Q92800:0.323 C:Q15022:0.271 |
|||||
| 7ktp | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | VAL | B:232 | B:232 | 94.0 | 0.606 | T | -69.6 | -34.8 | 19.0 | 0.123 | 0.483 |
A:Q92800:0.329 C:Q15022:0.265 |
|||||
| 5wg6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2018-06-27 | VAL | B:233 | B:232 | 98.0 | 0.632 | S | -80.3 | -42.1 | 22.0 | 0.142 | 0.49 |
A:Q15910+Q15022:0.49 |
|||||
| VAL | D:233 | D:232 | 95.0 | 0.613 | T | -61.9 | -37.3 | NA | NA | NA | |||||||||||||
| 3jpx | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-10-20 | VAL | A:193 | A:232 | 108.0 | 0.697 | T | -71.2 | -23.3 | 108.0 | 0.697 | 0.0 |
HOH |
2.766 |
N |
O |
||
| 3jzg | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | VAL | A:193 | A:232 | 122.0 | 0.787 | T | -66.5 | -25.0 | 122.0 | 0.787 | 0.0 |
HOH |
2.661 |
N |
O |
||
| 3jzh | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | VAL | A:193 | A:232 | 111.0 | 0.716 | T | -68.7 | -30.1 | 111.0 | 0.716 | 0.0 |
HOH |
2.837 |
N |
O |
||
| 7kxt | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:193 | A:232 | 77.0 | 0.497 | T | -49.4 | -50.0 | 77.0 | 0.497 | 0.0 |
UNX HOH |
6.625 5.920 |
N N |
UNK O |
||
| VAL | B:193 | B:232 | 77.0 | 0.497 | T | -50.3 | -49.9 | NA | NA | NA | |||||||||||||
| 5wp3 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-09-13 | VAL | A:159 | A:232 | 84.0 | NA | T | -39.5 | -51.6 | 84.0 | NA | NA |
UNX |
7.569 |
CB |
UNK |
||
| 5h13 | 1 | O75530 | 99.19 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:167 | A:232 | 86.0 | 0.555 | T | -45.4 | -51.0 | 86.0 | 0.555 | 0.0 |
HOH |
5.685 |
N |
O |
||
| 3jzn | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | VAL | A:157 | A:232 | 109.0 | 0.703 | S | -77.5 | -26.9 | 109.0 | 0.703 | 0.0 |
HOH |
4.861 |
N |
O |
||
| 3k26 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | VAL | A:157 | A:232 | 105.0 | 0.677 | T | -71.0 | -17.1 | 105.0 | 0.677 | 0.0 |
HOH |
2.989 |
N |
O |
||
| 3k27 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | VAL | A:157 | A:232 | 111.0 | 0.716 | T | -71.0 | -22.5 | 111.0 | 0.716 | 0.0 |
HOH |
2.848 |
N |
O |
||
| 6sfb | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | VAL | A:157 | A:232 | 96.0 | 0.619 | T | -52.4 | -46.0 | 96.0 | 0.619 | 0.0 |
HOH |
4.857 |
O |
O |
||
| VAL | B:157 | B:232 | 95.0 | 0.613 | T | -55.0 | -41.4 | NA | NA | NA | |||||||||||||
| 6sfc | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | VAL | A:157 | A:232 | 94.0 | 0.606 | S | -55.3 | -56.8 | 94.0 | 0.606 | 0.0 |
HOH |
5.558 |
N |
O |
||
| VAL | B:157 | B:232 | 94.0 | 0.606 | T | -44.8 | -49.5 | NA | NA | NA | |||||||||||||
| 6yvi | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | VAL | A:157 | A:232 | 93.0 | 0.6 | S | -59.5 | -68.0 | 93.0 | 0.6 | 0.0 |
HOH |
3.147 |
CA |
O |
||
| VAL | B:157 | B:232 | 95.0 | 0.613 | T | -57.5 | -35.7 | NA | NA | NA | |||||||||||||
| 6yvj | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | VAL | A:157 | A:232 | 91.0 | 0.587 | S | -65.9 | -48.8 | 91.0 | 0.587 | 0.0 |
HOH |
3.015 |
O |
O |
||
| VAL | B:157 | B:232 | 94.0 | 0.606 | T | -48.4 | -45.1 | NA | NA | NA | |||||||||||||
| 7p3c | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | VAL | A:157 | A:232 | 90.0 | 0.581 | T | -42.9 | -70.3 | 90.0 | 0.581 | 0.0 |
HOH |
4.293 |
O |
O |
||
| VAL | B:157 | B:232 | 94.0 | 0.606 | T | -55.2 | -42.0 | NA | NA | NA | |||||||||||||
| 7p3g | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | VAL | A:157 | A:232 | 91.0 | 0.587 | S | -63.0 | -48.3 | 91.0 | 0.587 | 0.0 |
HOH |
5.466 |
N |
O |
||
| VAL | B:157 | B:232 | 95.0 | 0.613 | T | -54.4 | -43.1 | NA | NA | NA | |||||||||||||
| 7p3j | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | VAL | A:157 | A:232 | 97.0 | 0.626 | S | -57.4 | -62.2 | 97.0 | 0.626 | 0.0 |
HOH |
3.946 |
O |
O |
||
| VAL | B:157 | B:232 | 100.0 | 0.645 | T | -50.7 | -40.6 | NA | NA | NA | |||||||||||||
| 5gsa | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-01 | VAL | A:158 | A:232 | 94.0 | 0.606 | T | -52.9 | -46.5 | 94.0 | 0.606 | 0.0 |
HOH |
3.847 |
O |
O |
||
| VAL | B:158 | B:232 | 96.0 | 0.619 | T | -52.6 | -55.7 | NA | NA | NA | |||||||||||||
| 5h14 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:158 | A:232 | 92.0 | 0.594 | T | -48.3 | -53.7 | 92.0 | 0.594 | 0.0 |
HOH |
3.985 |
CG1 |
O |
||
| VAL | B:158 | B:232 | 92.0 | 0.594 | T | -46.7 | -49.8 | NA | NA | NA | |||||||||||||
| 5h15 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:158 | A:232 | 93.0 | 0.6 | T | -46.9 | -50.0 | 93.0 | 0.6 | 0.0 |
HOH |
4.500 |
O |
O |
||
| VAL | B:158 | B:232 | 94.0 | 0.606 | T | -47.9 | -50.7 | NA | NA | NA | |||||||||||||
| 5h17 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:158 | A:232 | 95.0 | 0.613 | T | -42.8 | -56.5 | 95.0 | 0.613 | 0.0 |
HOH |
5.748 |
N |
O |
||
| 5h19 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:158 | A:232 | 93.0 | 0.6 | T | -45.4 | -55.0 | 93.0 | 0.6 | 0.0 |
HOH |
5.655 |
N |
O |
||
| 5h24 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:158 | A:232 | 100.0 | 0.645 | T | -48.2 | -55.1 | 100.0 | 0.645 | 0.0 |
HOH |
7.369 |
O |
O |
||
| VAL | B:158 | B:232 | 98.0 | 0.632 | T | -50.7 | -51.1 | NA | NA | NA | |||||||||||||
| 5h25 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:158 | A:232 | 107.0 | 0.69 | S | -51.3 | -41.7 | 107.0 | 0.69 | 0.0 |
HOH |
7.790 |
CB |
O |
||
| VAL | B:158 | B:232 | 97.0 | 0.626 | S | -59.5 | -37.8 | NA | NA | NA | |||||||||||||
| 5ttw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:158 | A:232 | 89.0 | 0.574 | T | -57.6 | -52.5 | 89.0 | 0.574 | 0.0 |
UNX HOH |
9.492 2.372 |
O O |
UNK O |
||
| VAL | C:158 | C:232 | 103.0 | 0.665 | T | -70.6 | -40.4 | NA | NA | NA | |||||||||||||
| 5u5h | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:158 | A:232 | 112.0 | 0.723 | T | -60.4 | -29.2 | 112.0 | 0.723 | 0.0 |
HOH |
2.910 |
N |
O |
||
| 5u5k | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:158 | A:232 | 140.0 | 0.903 | T | -55.5 | -39.1 | 140.0 | 0.903 | 0.0 |
HOH |
3.597 |
O |
O |
||
| 5u5t | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:158 | A:232 | 96.0 | 0.619 | T | -47.6 | -48.7 | 96.0 | 0.619 | 0.0 |
HOH |
3.888 |
O |
O |
||
| VAL | B:158 | B:232 | 93.0 | 0.6 | T | -42.4 | -55.0 | NA | NA | NA | |||||||||||||
| 5u62 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:158 | A:232 | 98.0 | 0.632 | T | -43.7 | -51.6 | 98.0 | 0.632 | 0.0 |
YT3 HOH |
7.808 3.657 |
CB N |
Y O |
||
| VAL | B:158 | B:232 | 93.0 | 0.6 | T | -45.3 | -56.0 | NA | NA | NA | |||||||||||||
| 6lo2 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-07-07 | VAL | A:158 | A:232 | 100.0 | 0.645 | T | -43.0 | -55.0 | 100.0 | 0.645 | 0.0 |
HOH |
4.380 |
O |
O |
||
| VAL | B:158 | B:232 | 92.0 | 0.594 | T | -46.9 | -46.2 | NA | NA | NA | |||||||||||||
| 6v3x | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | VAL | A:158 | A:232 | 148.0 | 0.955 | S | -59.5 | -41.4 | 148.0 | 0.955 | 0.0 |
HOH |
4.341 |
N |
O |
||
| 4x3e | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2015-01-21 | VAL | A:158 | A:232 | 80.0 | 0.516 | T | -54.0 | -53.2 | 80.0 | 0.516 | 0.0 |
HOH |
3.829 |
CG1 |
O |
||
| 5hyn | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-11 | VAL | B:158 | B:232 | 102.0 | 0.658 | T | -64.4 | -40.8 | 29.0 | 0.187 | 0.471 |
A:Q15910:0.29 C:Q15022:0.29 |
|||||
| VAL | G:158 | G:232 | 96.0 | 0.619 | T | -60.5 | -38.9 | NA | NA | NA | |||||||||||||
| VAL | L:158 | L:232 | 92.0 | 0.594 | T | -61.8 | -35.5 | NA | NA | NA | |||||||||||||
| VAL | Q:158 | R:232 | 96.0 | 0.619 | T | -62.6 | -39.6 | NA | NA | NA | |||||||||||||
| 5ls6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-22 | VAL | B:158 | B:232 | 90.0 | 0.581 | S | -73.6 | -62.3 | 21.0 | 0.135 | 0.446 |
A:Q15910:0.258 C:Q15022:0.29 |
|||||
| VAL | E:158 | E:232 | 101.0 | 0.652 | S | -78.3 | -43.8 | NA | NA | NA | |||||||||||||
| VAL | H:158 | H:232 | 100.0 | 0.645 | S | -82.2 | -49.0 | NA | NA | NA | |||||||||||||
| VAL | K:158 | K:232 | 91.0 | 0.587 | S | -79.0 | -53.6 | NA | NA | NA | |||||||||||||
| 5u69 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | VAL | A:160 | A:232 | 109.0 | 0.703 | T | -67.0 | -23.6 | 109.0 | 0.703 | 0.0 |
HOH |
2.959 |
N |
O |
||
| 5u6d | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | VAL | A:160 | A:232 | 108.0 | 0.697 | T | -66.9 | -30.4 | 108.0 | 0.697 | 0.0 |
HOH |
3.277 |
N |
O |
||
| 5u8a | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | VAL | A:160 | A:232 | 112.0 | 0.723 | T | -67.9 | -23.9 | 112.0 | 0.723 | 0.0 |
HOH |
2.924 |
N |
O |
||
| 5u8f | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | VAL | A:160 | A:232 | 104.0 | 0.671 | T | -69.7 | -23.1 | 104.0 | 0.671 | 0.0 |
HOH |
2.844 |
N |
O |
||
| 3iiw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-09-15 | VAL | A:156 | A:232 | 100.0 | 0.645 | T | -70.5 | -22.8 | 100.0 | 0.645 | 0.0 |
HOH |
2.906 |
N |
O |
||
| 5k0m | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | VAL | A:163 | A:232 | 120.0 | 0.774 | T | -67.6 | -26.9 | 120.0 | 0.774 | 0.0 |
HOH |
2.896 |
N |
O |
||
| 5wuk | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2017-05-03 | VAL | A:157 | A:232 | 105.0 | 0.677 | T | -55.6 | -42.9 | 105.0 | 0.677 | 0.0 |
HOH |
2.928 |
N |
O |
||
| 6u4y | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2020-07-08 | VAL | D:157 | D:232 | 106.0 | 0.684 | T | -58.6 | -36.3 | 106.0 | 0.684 | 0.0 | ||||||
| VAL | E:157 | E:232 | 97.0 | 0.626 | S | -75.4 | -19.9 | 97.0 | 0.626 | 0.0 | |||||||||||||
| VAL | F:157 | F:232 | 86.0 | 0.555 | T | -60.5 | -26.4 | 86.0 | 0.555 | 0.0 | |||||||||||||
| 6w7f | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | VAL | A:159 | A:232 | 98.0 | 0.632 | T | -56.6 | -36.6 | 98.0 | 0.632 | 0.0 |
HOH |
2.613 |
O |
O |
||
| 6w7g | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | VAL | A:159 | A:232 | 103.0 | 0.665 | T | -60.3 | -28.5 | 103.0 | 0.665 | 0.0 |
Q3A HOH |
2.658 2.529 |
CG1 O |
H1 O |
||
| 7msb | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | VAL | A:159 | A:232 | 79.0 | NA | T | -57.1 | -37.6 | 79.0 | NA | NA |
HOH |
3.032 |
N |
O |
||
| 7msd | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | VAL | A:159 | A:232 | 97.0 | 0.626 | T | -53.9 | -42.6 | 97.0 | 0.626 | 0.0 |
HOH |
2.702 |
O |
O |
||
| 3iiy | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | VAL | A:156 | A:232 | 108.0 | 0.697 | T | -62.7 | -42.6 | 108.0 | 0.697 | 0.0 |
HOH |
3.075 |
N |
O |
||
| 3ij0 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | VAL | A:156 | A:232 | 105.0 | 0.677 | T | -57.0 | -35.9 | 105.0 | 0.677 | 0.0 |
HOH |
3.010 |
O |
O |
||
| 3ij1 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | VAL | A:156 | A:232 | 103.0 | 0.665 | T | -56.6 | -39.0 | 103.0 | 0.665 | 0.0 |
HOH |
3.193 |
N |
O |
||
| 3ijc | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | VAL | A:156 | A:232 | 75.0 | 0.484 | T | -49.1 | -55.1 | 75.0 | 0.484 | 0.0 |
HOH |
3.579 |
O |
O |
||
| 2qxv | 1 | Q921E6 | 100.0 | 0.0 |
X-RAY |
2007-08-28 | VAL | A:152 | A:231 | 85.0 | 0.548 | T | -42.4 | -50.7 | 85.0 | 0.548 | 0.0 |
HOH |
2.823 |
O |
O |
||
| 4w2r | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | VAL | C:153 | E:218 | 102.0 | 0.658 | T | -57.8 | -28.8 | NA | NA | NA | ||||||
| VAL | D:153 | F:218 | 105.0 | 0.677 | T | -59.9 | -27.3 | 25.0 | 0.161 | 0.516 |
A:G1KPH4:0.323 F:Q15022:0.31 |
||||||||||||
| 5ij7 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | VAL | C:153 | E:218 | 100.0 | 0.645 | T | -49.6 | -40.4 | 22.0 | 0.142 | 0.503 |
A:G1KPH4+Q15910:0.323 E:Q15022:0.29 |
HOH |
4.015 |
O |
O |
|
| VAL | D:153 | F:218 | 99.0 | 0.639 | T | -48.7 | -41.3 | NA | NA | NA | |||||||||||||
| 5ij8 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | VAL | C:153 | E:218 | 96.0 | 0.619 | T | -54.6 | -41.2 | NA | NA | NA | ||||||
| VAL | D:153 | F:218 | 97.0 | 0.626 | T | -53.5 | -41.0 | 23.0 | 0.148 | 0.478 |
A:G1KPH4+Q15910:0.31 F:Q15022:0.271 |
||||||||||||
| 6b3w | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | VAL | C:153 | E:218 | 101.0 | 0.652 | T | -53.3 | -31.8 | NA | NA | NA | ||||||
| VAL | D:153 | F:218 | 99.0 | 0.639 | T | -61.8 | -22.2 | 23.0 | 0.148 | 0.491 |
A:G1KPH4:0.297 F:Q15022:0.303 |
||||||||||||
| 6v3y | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | VAL | A:152 | A:232 | 112.0 | 0.723 | T | -70.9 | -21.8 | 112.0 | 0.723 | 0.0 |
HOH |
2.943 |
N |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o75530-f1 | 1 | O75530 | 100.0 | 0.0 | VAL | A:232 | A:232 | 78.0 | 0.503 | T | -60.8 | -40.9 | |