Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85975286 . G A CCDS8273.1:NM_003797.3:c.707aGa>aAa_NP_003788.2:p.236R>K Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
2018-01-24 ARG D:236 L:236 182.0 0.809 -81.1 -5.4 86.0 0.382 0.427 C:Q15910:0.147
K:Q15910:0.28
6c24 5 O75530 100.0 0.0 EM
2018-01-24 ARG E:236 L:236 212.0 0.942 S -117.1 -10.6 131.0 0.582 0.36 D:Q15910:0.36
6wkr 3 O75530 100.0 0.0 EM
2021-02-03 ARG C:236 L:236 185.0 0.822 S -94.3 -13.3 129.0 0.573 0.249 E:Q15910:0.249
7kso 2 O75530 100.0 0.0 EM
2021-02-03 ARG B:236 B:236 173.0 0.769 S -89.4 20.7 127.0 0.564 0.205 A:Q92800:0.204
7ksr 4 O75530 100.0 0.0 EM
2021-02-03 ARG D:236 B:236 170.0 0.756 S -90.5 21.3 122.0 0.542 0.214 A:Q92800:0.213
7ktp 2 O75530 100.0 0.0 EM
2021-02-03 ARG B:236 B:236 166.0 0.738 S -90.6 21.4 117.0 0.52 0.218 A:Q92800:0.218
5wg6 2 O75530 100.0 0.0 X-RAY
2018-06-27 ARG B:237 B:236 216.0 0.96 S -74.2 -9.7 175.0 0.778 0.182 A:Q15910+Q15022:0.182
A9G
8.011
O
C02
ARG D:237 D:236 182.0 0.809 S -110.4 -21.4 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
2009-10-20 ARG A:197 A:236 151.0 0.671 S -111.0 18.2 151.0 0.671 0.0 HOH
2.687
NE
O
3jzg 1 O75530 100.0 0.0 X-RAY
2009-12-15 ARG A:197 A:236 107.0 0.476 S -109.7 16.9 107.0 0.476 0.0 HOH
2.474
NH2
O
3jzh 1 O75530 100.0 0.0 X-RAY
2009-12-15 ARG A:197 A:236 153.0 0.68 S -107.6 10.9 153.0 0.68 0.0 HOH
2.756
NH1
O
7kxt 1 O75530 100.0 0.0 X-RAY
2021-02-24 ARG A:197 A:236 136.0 0.604 S -94.9 7.6 136.0 0.604 0.0 UNX
HOH
9.528
3.142
NH1
NH1
UNK
O
ARG B:197 B:236 140.0 0.622 S -95.0 8.3 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
2017-09-13 ARG A:163 A:236 89.0 NA S -67.2 -16.5 89.0 NA NA
5h13 1 O75530 99.19 0.0 X-RAY
2017-01-25 ARG A:171 A:236 138.0 0.613 S -98.3 3.7 138.0 0.613 0.0 HOH
3.585
NH1
O
3jzn 1 O75530 100.0 0.0 X-RAY
2009-12-15 ARG A:161 A:236 153.0 0.68 S -110.1 22.3 153.0 0.68 0.0 HOH
5.093
N
O
3k26 1 O75530 100.0 0.0 X-RAY
2009-12-15 ARG A:161 A:236 146.0 0.649 S -108.2 9.2 146.0 0.649 0.0 HOH
2.859
O
O
3k27 1 O75530 100.0 0.0 X-RAY
2009-12-15 ARG A:161 A:236 150.0 0.667 S -113.3 10.2 150.0 0.667 0.0 HOH
2.945
O
O
6sfb 1 O75530 100.0 0.0 X-RAY
2019-09-25 ARG A:161 A:236 187.0 0.831 S -109.1 10.1 187.0 0.831 0.0 HOH
2.821
O
O
ARG B:161 B:236 194.0 0.862 S -102.7 -0.3 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
2019-09-25 ARG A:161 A:236 189.0 0.84 S -100.3 0.7 189.0 0.84 0.0 HOH
2.733
O
O
ARG B:161 B:236 179.0 0.796 S -100.2 0.7 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
2021-05-12 ARG A:161 A:236 200.0 0.889 S -97.4 1.3 200.0 0.889 0.0 HOH
2.890
NH1
O
ARG B:161 B:236 183.0 0.813 S -96.2 -0.9 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
2021-05-12 ARG A:161 A:236 192.0 0.853 S -100.7 4.3 192.0 0.853 0.0 HOH
2.875
O
O
ARG B:161 B:236 191.0 0.849 S -101.0 4.0 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
2021-12-08 ARG A:161 A:236 190.0 0.844 S -105.3 5.1 190.0 0.844 0.0 HOH
2.887
O
O
ARG B:161 B:236 186.0 0.827 S -103.8 3.8 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
2021-12-08 ARG A:161 A:236 192.0 0.853 S -104.9 -4.2 192.0 0.853 0.0 HOH
3.280
O
O
ARG B:161 B:236 170.0 0.756 S -105.5 -4.5 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
2021-12-08 ARG A:161 A:236 186.0 0.827 S -99.5 4.5 186.0 0.827 0.0 HOH
2.996
O
O
ARG B:161 B:236 179.0 0.796 S -98.7 4.3 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
2017-02-01 ARG A:162 A:236 191.0 0.849 S -89.2 -24.4 191.0 0.849 0.0 HOH
2.842
NH2
O
ARG B:162 B:236 208.0 0.924 S -94.0 -9.6 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:162 A:236 199.0 0.884 S -101.1 -1.1 199.0 0.884 0.0 HOH
3.208
O
O
ARG B:162 B:236 196.0 0.871 S -98.2 -0.5 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:162 A:236 191.0 0.849 S -101.5 -4.5 191.0 0.849 0.0 HOH
2.818
NH1
O
ARG B:162 B:236 203.0 0.902 S -106.2 -1.1 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:162 A:236 123.0 0.547 S -101.5 -12.0 123.0 0.547 0.0 HOH
3.383
O
O
5h19 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:162 A:236 142.0 0.631 S -96.6 3.5 142.0 0.631 0.0 HOH
3.633
NH1
O
5h24 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:162 A:236 211.0 0.938 S -100.8 3.1 211.0 0.938 0.0 HOH
3.380
O
O
ARG B:162 B:236 179.0 0.796 S -92.9 -11.2 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:162 A:236 224.0 0.996 S -85.0 0.4 224.0 0.996 0.0
ARG B:162 B:236 198.0 0.88 S -88.6 -6.6 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
2017-01-11 ARG A:162 A:236 127.0 NA S -107.8 8.3 127.0 NA NA UNX
HOH
7.546
2.735
NE
O
UNK
O
ARG C:162 C:236 140.0 0.622 S -105.5 1.8 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
2017-01-11 ARG A:162 A:236 170.0 0.756 S -102.7 6.5 170.0 0.756 0.0 HOH
2.886
O
O
5u5k 1 O75530 100.0 0.0 X-RAY
2017-01-11 ARG A:162 A:236 76.0 NA S -96.9 3.9 76.0 NA NA HOH
3.665
CB
O
5u5t 1 O75530 100.0 0.0 X-RAY
2017-01-11 ARG A:162 A:236 138.0 0.613 S -105.4 6.7 138.0 0.613 0.0 HOH
2.782
NH2
O
ARG B:162 B:236 201.0 0.893 S -106.7 5.9 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
2017-01-11 ARG A:162 A:236 137.0 0.609 S -105.4 5.1 137.0 0.609 0.0 HOH
2.765
NH2
O
ARG B:162 B:236 203.0 0.902 S -104.4 3.3 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
2021-07-07 ARG A:162 A:236 210.0 0.933 S -98.3 -3.1 210.0 0.933 0.0 HOH
3.437
CG
O
ARG B:162 B:236 188.0 0.836 S -95.7 -4.5 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
2021-05-26 ARG A:162 A:236 87.0 NA S -100.2 4.5 87.0 NA NA HOH
3.936
CA
O
4x3e 1 O75530 100.0 0.0 X-RAY
2015-01-21 ARG A:162 A:236 147.0 0.653 S -116.2 8.3 147.0 0.653 0.0 HOH
2.738
O
O
5hyn 2 O75530 100.0 0.0 X-RAY
2016-05-11 ARG B:162 B:236 216.0 0.96 S -87.3 -23.5 93.0 0.413 0.547 A:Q15910:0.547
ARG G:162 G:236 209.0 0.929 S -91.2 -26.1 NA NA NA
ARG L:162 L:236 203.0 0.902 S -90.5 -20.3 NA NA NA
ARG Q:162 R:236 202.0 0.898 S -92.3 -18.3 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
2017-02-22 ARG B:162 B:236 209.0 0.929 S -103.6 -25.4 89.0 0.396 0.533 A:Q15910:0.533
74D
3.549
O
CBK
ARG E:162 E:236 218.0 0.969 S -93.4 -18.6 NA NA NA
ARG H:162 H:236 214.0 0.951 S -86.8 -7.0 NA NA NA
ARG K:162 K:236 206.0 0.916 S -99.3 -15.7 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
2017-03-15 ARG A:164 A:236 150.0 0.667 S -113.3 10.0 150.0 0.667 0.0 HOH
2.771
O
O
5u6d 1 O75530 100.0 0.0 X-RAY
2017-03-15 ARG A:164 A:236 127.0 0.564 S -111.4 10.9 127.0 0.564 0.0 HOH
3.902
CA
O
5u8a 1 O75530 100.0 0.0 X-RAY
2017-03-15 ARG A:164 A:236 156.0 0.693 S -112.0 7.9 156.0 0.693 0.0 HOH
2.818
O
O
5u8f 1 O75530 100.0 0.0 X-RAY
2017-03-15 ARG A:164 A:236 149.0 0.662 S -112.0 8.7 149.0 0.662 0.0 HOH
2.826
O
O
3iiw 1 O75530 100.0 0.0 X-RAY
2009-09-15 ARG A:160 A:236 142.0 0.631 S -102.3 6.2 142.0 0.631 0.0 HOH
2.900
O
O
5k0m 1 O75530 100.0 0.0 X-RAY
2017-01-25 ARG A:167 A:236 128.0 0.569 S -115.3 10.6 128.0 0.569 0.0 HOH
2.862
NH1
O
5wuk 1 O75530 99.73 0.0 X-RAY
2017-05-03 ARG A:161 A:236 154.0 0.684 S -110.9 14.3 154.0 0.684 0.0 HOH
3.006
NH1
O
6u4y 2 O75530 100.0 0.0 X-RAY
2020-07-08 ARG D:161 D:236 223.0 0.991 S -96.9 9.2 223.0 0.991 0.0
ARG E:161 E:236 205.0 0.911 S -104.4 0.7 205.0 0.911 0.0
ARG F:161 F:236 200.0 0.889 S -93.7 11.9 200.0 0.889 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
2020-07-08 ARG A:163 A:236 110.0 NA S -105.3 10.8 110.0 NA NA HOH
3.378
O
O
6w7g 1 O75530 99.73 0.0 X-RAY
2020-07-08 ARG A:163 A:236 96.0 NA S -103.9 3.4 96.0 NA NA Q3A
HOH
7.484
2.717
O
O
H19
O
7msb 1 O75530 99.73 0.0 X-RAY
2021-10-20 ARG A:163 A:236 99.0 NA S -105.7 3.9 99.0 NA NA HOH
2.695
O
O
7msd 1 O75530 99.73 0.0 X-RAY
2021-10-20 ARG A:163 A:236 121.0 0.538 S -97.5 -2.5 121.0 0.538 0.0 HOH
2.904
NH1
O
3iiy 1 O75530 99.73 0.0 X-RAY
2009-09-15 ARG A:160 A:236 149.0 0.662 S -101.3 12.8 149.0 0.662 0.0 HOH
2.898
NE
O
3ij0 1 O75530 99.73 0.0 X-RAY
2009-09-15 ARG A:160 A:236 150.0 0.667 S -99.8 15.2 150.0 0.667 0.0 HOH
2.627
NE
O
3ij1 1 O75530 99.73 0.0 X-RAY
2009-09-15 ARG A:160 A:236 146.0 0.649 S -109.1 8.3 146.0 0.649 0.0 HOH
2.561
O
O
3ijc 1 O75530 99.73 0.0 X-RAY
2009-09-15 ARG A:160 A:236 129.0 0.573 S -100.4 6.8 129.0 0.573 0.0 HOH
3.222
NE
O
2qxv 1 Q921E6 100.0 0.0 X-RAY
2007-08-28 ARG A:156 A:235 190.0 0.844 S -105.8 3.9 190.0 0.844 0.0 HOH
2.668
O
O
4w2r 2 O75530 100.0 0.0 X-RAY
2017-12-27 ARG C:157 E:222 188.0 0.836 S -90.6 -2.4 NA NA NA
ARG D:157 F:222 190.0 0.844 S -86.5 -1.0 157.0 0.698 0.146 A:G1KPH4:0.147
CJD
5.583
O
O28
5ij7 2 O75530 100.0 0.0 X-RAY
2016-05-04 ARG C:157 E:222 196.0 0.871 S -90.9 -9.6 188.0 0.836 0.035 A:G1KPH4+Q15910:0.036
6BN
HOH
2.853
5.074
O
N
O35
O
ARG D:157 F:222 197.0 0.876 S -89.6 -12.9 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
2016-05-04 ARG C:157 E:222 180.0 0.8 S -79.0 -15.7 NA NA NA
ARG D:157 F:222 185.0 0.822 S -78.5 -15.8 162.0 0.72 0.102 A:G1KPH4+Q15910:0.102
6BN
2.654
O
O35
6b3w 2 O75530 100.0 0.0 X-RAY
2017-12-27 ARG C:157 E:222 182.0 0.809 S -82.3 -6.4 NA NA NA
ARG D:157 F:222 180.0 0.8 S -81.4 -0.3 156.0 0.693 0.107 A:G1KPH4:0.107
CJG
6.576
O
C29
6v3y 1 O75530 100.0 0.0 X-RAY
2021-05-26 ARG A:156 A:236 122.0 NA S -109.2 11.0 122.0 NA NA HOH
3.502
CZ
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 ARG A:236 A:236 153.0 0.68 S -102.0 -2.9