Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85975286 . G A CCDS8273.1:NM_003797.3:c.707aGa>aAa_NP_003788.2:p.236R>K Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 ARG D:236 L:236 182.0 0.809 -81.1 -5.4 86.0 0.382 0.427 C:Q15910:0.147
K:Q15910:0.28
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 ARG E:236 L:236 212.0 0.942 S -117.1 -10.6 131.0 0.582 0.36 D:Q15910:0.36
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 ARG C:236 L:236 185.0 0.822 S -94.3 -13.3 129.0 0.573 0.249 E:Q15910:0.249
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 ARG B:236 B:236 173.0 0.769 S -89.4 20.7 127.0 0.564 0.205 A:Q92800:0.204
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 ARG D:236 B:236 170.0 0.756 S -90.5 21.3 122.0 0.542 0.214 A:Q92800:0.213
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 ARG B:236 B:236 166.0 0.738 S -90.6 21.4 117.0 0.52 0.218 A:Q92800:0.218
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 ARG B:237 B:236 216.0 0.96 S -74.2 -9.7 175.0 0.778 0.182 A:Q15910+Q15022:0.182
 A9G
 8.011
 O
 C02
ARG D:237 D:236 182.0 0.809 S -110.4 -21.4 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 ARG A:197 A:236 151.0 0.671 S -111.0 18.2 151.0 0.671 0.0 HOH
 2.687
 NE
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:197 A:236 107.0 0.476 S -109.7 16.9 107.0 0.476 0.0 HOH
 2.474
 NH2
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:197 A:236 153.0 0.68 S -107.6 10.9 153.0 0.68 0.0 HOH
 2.756
 NH1
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 ARG A:197 A:236 136.0 0.604 S -94.9 7.6 136.0 0.604 0.0 UNX
HOH
 9.528
3.142
 NH1
NH1
 UNK
O
ARG B:197 B:236 140.0 0.622 S -95.0 8.3 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 ARG A:163 A:236 89.0 NA S -67.2 -16.5 89.0 NA NA
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 ARG A:171 A:236 138.0 0.613 S -98.3 3.7 138.0 0.613 0.0 HOH
 3.585
 NH1
 O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:161 A:236 153.0 0.68 S -110.1 22.3 153.0 0.68 0.0 HOH
 5.093
 N
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:161 A:236 146.0 0.649 S -108.2 9.2 146.0 0.649 0.0 HOH
 2.859
 O
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:161 A:236 150.0 0.667 S -113.3 10.2 150.0 0.667 0.0 HOH
 2.945
 O
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ARG A:161 A:236 187.0 0.831 S -109.1 10.1 187.0 0.831 0.0 HOH
 2.821
 O
 O
ARG B:161 B:236 194.0 0.862 S -102.7 -0.3 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ARG A:161 A:236 189.0 0.84 S -100.3 0.7 189.0 0.84 0.0 HOH
 2.733
 O
 O
ARG B:161 B:236 179.0 0.796 S -100.2 0.7 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ARG A:161 A:236 200.0 0.889 S -97.4 1.3 200.0 0.889 0.0 HOH
 2.890
 NH1
 O
ARG B:161 B:236 183.0 0.813 S -96.2 -0.9 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ARG A:161 A:236 192.0 0.853 S -100.7 4.3 192.0 0.853 0.0 HOH
 2.875
 O
 O
ARG B:161 B:236 191.0 0.849 S -101.0 4.0 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:161 A:236 190.0 0.844 S -105.3 5.1 190.0 0.844 0.0 HOH
 2.887
 O
 O
ARG B:161 B:236 186.0 0.827 S -103.8 3.8 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:161 A:236 192.0 0.853 S -104.9 -4.2 192.0 0.853 0.0 HOH
 3.280
 O
 O
ARG B:161 B:236 170.0 0.756 S -105.5 -4.5 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:161 A:236 186.0 0.827 S -99.5 4.5 186.0 0.827 0.0 HOH
 2.996
 O
 O
ARG B:161 B:236 179.0 0.796 S -98.7 4.3 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 ARG A:162 A:236 191.0 0.849 S -89.2 -24.4 191.0 0.849 0.0 HOH
 2.842
 NH2
 O
ARG B:162 B:236 208.0 0.924 S -94.0 -9.6 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:162 A:236 199.0 0.884 S -101.1 -1.1 199.0 0.884 0.0 HOH
 3.208
 O
 O
ARG B:162 B:236 196.0 0.871 S -98.2 -0.5 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:162 A:236 191.0 0.849 S -101.5 -4.5 191.0 0.849 0.0 HOH
 2.818
 NH1
 O
ARG B:162 B:236 203.0 0.902 S -106.2 -1.1 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:162 A:236 123.0 0.547 S -101.5 -12.0 123.0 0.547 0.0 HOH
 3.383
 O
 O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:162 A:236 142.0 0.631 S -96.6 3.5 142.0 0.631 0.0 HOH
 3.633
 NH1
 O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:162 A:236 211.0 0.938 S -100.8 3.1 211.0 0.938 0.0 HOH
 3.380
 O
 O
ARG B:162 B:236 179.0 0.796 S -92.9 -11.2 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:162 A:236 224.0 0.996 S -85.0 0.4 224.0 0.996 0.0
ARG B:162 B:236 198.0 0.88 S -88.6 -6.6 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:162 A:236 127.0 NA S -107.8 8.3 127.0 NA NA UNX
HOH
 7.546
2.735
 NE
O
 UNK
O
ARG C:162 C:236 140.0 0.622 S -105.5 1.8 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:162 A:236 170.0 0.756 S -102.7 6.5 170.0 0.756 0.0 HOH
 2.886
 O
 O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:162 A:236 76.0 NA S -96.9 3.9 76.0 NA NA HOH
 3.665
 CB
 O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:162 A:236 138.0 0.613 S -105.4 6.7 138.0 0.613 0.0 HOH
 2.782
 NH2
 O
ARG B:162 B:236 201.0 0.893 S -106.7 5.9 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:162 A:236 137.0 0.609 S -105.4 5.1 137.0 0.609 0.0 HOH
 2.765
 NH2
 O
ARG B:162 B:236 203.0 0.902 S -104.4 3.3 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 ARG A:162 A:236 210.0 0.933 S -98.3 -3.1 210.0 0.933 0.0 HOH
 3.437
 CG
 O
ARG B:162 B:236 188.0 0.836 S -95.7 -4.5 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ARG A:162 A:236 87.0 NA S -100.2 4.5 87.0 NA NA HOH
 3.936
 CA
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 ARG A:162 A:236 147.0 0.653 S -116.2 8.3 147.0 0.653 0.0 HOH
 2.738
 O
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 ARG B:162 B:236 216.0 0.96 S -87.3 -23.5 93.0 0.413 0.547 A:Q15910:0.547
ARG G:162 G:236 209.0 0.929 S -91.2 -26.1 NA NA NA
ARG L:162 L:236 203.0 0.902 S -90.5 -20.3 NA NA NA
ARG Q:162 R:236 202.0 0.898 S -92.3 -18.3 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 ARG B:162 B:236 209.0 0.929 S -103.6 -25.4 89.0 0.396 0.533 A:Q15910:0.533
 74D
 3.549
 O
 CBK
ARG E:162 E:236 218.0 0.969 S -93.4 -18.6 NA NA NA
ARG H:162 H:236 214.0 0.951 S -86.8 -7.0 NA NA NA
ARG K:162 K:236 206.0 0.916 S -99.3 -15.7 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:164 A:236 150.0 0.667 S -113.3 10.0 150.0 0.667 0.0 HOH
 2.771
 O
 O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:164 A:236 127.0 0.564 S -111.4 10.9 127.0 0.564 0.0 HOH
 3.902
 CA
 O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:164 A:236 156.0 0.693 S -112.0 7.9 156.0 0.693 0.0 HOH
 2.818
 O
 O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:164 A:236 149.0 0.662 S -112.0 8.7 149.0 0.662 0.0 HOH
 2.826
 O
 O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 ARG A:160 A:236 142.0 0.631 S -102.3 6.2 142.0 0.631 0.0 HOH
 2.900
 O
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:167 A:236 128.0 0.569 S -115.3 10.6 128.0 0.569 0.0 HOH
 2.862
 NH1
 O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 ARG A:161 A:236 154.0 0.684 S -110.9 14.3 154.0 0.684 0.0 HOH
 3.006
 NH1
 O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 ARG D:161 D:236 223.0 0.991 S -96.9 9.2 223.0 0.991 0.0
ARG E:161 E:236 205.0 0.911 S -104.4 0.7 205.0 0.911 0.0
ARG F:161 F:236 200.0 0.889 S -93.7 11.9 200.0 0.889 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ARG A:163 A:236 110.0 NA S -105.3 10.8 110.0 NA NA HOH
 3.378
 O
 O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ARG A:163 A:236 96.0 NA S -103.9 3.4 96.0 NA NA Q3A
HOH
 7.484
2.717
 O
O
 H19
O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ARG A:163 A:236 99.0 NA S -105.7 3.9 99.0 NA NA HOH
 2.695
 O
 O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ARG A:163 A:236 121.0 0.538 S -97.5 -2.5 121.0 0.538 0.0 HOH
 2.904
 NH1
 O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:160 A:236 149.0 0.662 S -101.3 12.8 149.0 0.662 0.0 HOH
 2.898
 NE
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:160 A:236 150.0 0.667 S -99.8 15.2 150.0 0.667 0.0 HOH
 2.627
 NE
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:160 A:236 146.0 0.649 S -109.1 8.3 146.0 0.649 0.0 HOH
 2.561
 O
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:160 A:236 129.0 0.573 S -100.4 6.8 129.0 0.573 0.0 HOH
 3.222
 NE
 O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 ARG A:156 A:235 190.0 0.844 S -105.8 3.9 190.0 0.844 0.0 HOH
 2.668
 O
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ARG C:157 E:222 188.0 0.836 S -90.6 -2.4 NA NA NA
ARG D:157 F:222 190.0 0.844 S -86.5 -1.0 157.0 0.698 0.146 A:G1KPH4:0.147
 CJD
 5.583
 O
 O28
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ARG C:157 E:222 196.0 0.871 S -90.9 -9.6 188.0 0.836 0.035 A:G1KPH4+Q15910:0.036
 6BN
HOH
 2.853
5.074
 O
N
 O35
O
ARG D:157 F:222 197.0 0.876 S -89.6 -12.9 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ARG C:157 E:222 180.0 0.8 S -79.0 -15.7 NA NA NA
ARG D:157 F:222 185.0 0.822 S -78.5 -15.8 162.0 0.72 0.102 A:G1KPH4+Q15910:0.102
 6BN
 2.654
 O
 O35
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ARG C:157 E:222 182.0 0.809 S -82.3 -6.4 NA NA NA
ARG D:157 F:222 180.0 0.8 S -81.4 -0.3 156.0 0.693 0.107 A:G1KPH4:0.107
 CJG
 6.576
 O
 C29
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ARG A:156 A:236 122.0 NA S -109.2 11.0 122.0 NA NA HOH
 3.502
 CZ
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 ARG A:236 A:236 153.0 0.68 S -102.0 -2.9