Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85977165 . T A CCDS8273.1:NM_003797.3:c.767aTg>aAg_NP_003788.2:p.256M>K Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 MET D:256 L:256 12.0 0.065 S -86.5 -7.4 0.0 0.0 0.065 K:Q15910:0.065
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 MET E:256 L:256 14.0 0.076 T -76.6 -8.4 14.0 0.076 0.0
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 MET C:256 L:256 19.0 0.103 T -57.2 -22.2 2.0 0.011 0.092 E:Q15910:0.092
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 MET B:256 B:256 34.0 0.184 T -73.0 -13.2 34.0 0.184 0.0
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 MET D:256 B:256 33.0 0.178 T -72.2 -11.0 33.0 0.178 0.0
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 MET B:256 B:256 33.0 0.178 T -72.8 -13.6 33.0 0.178 0.0
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 MET B:257 B:256 51.0 0.276 T -75.1 19.5 51.0 0.276 0.0
MET D:257 D:256 63.0 0.341 T -75.8 -6.9 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 MET A:217 A:256 10.0 0.054 T -66.9 -15.8 10.0 0.054 0.0 HOH
 3.020
 N
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:217 A:256 12.0 0.065 T -72.6 -14.5 12.0 0.065 0.0 HOH
 2.926
 N
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:217 A:256 12.0 0.065 T -71.1 -8.6 12.0 0.065 0.0 HOH
 2.940
 N
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 MET A:217 A:256 52.0 0.281 T -68.5 -12.4 52.0 0.281 0.0 UNX
UNX
UNX
HOH
 9.837
7.797
8.927
6.278
 SD
CE
CE
CB
 UNK
UNK
UNK
O
MET B:217 B:256 52.0 0.281 T -67.6 -12.7 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 MET A:183 A:256 74.0 0.4 T -56.5 -32.1 74.0 0.4 0.0 UNX
 9.343
 CE
 UNK
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 MET A:191 A:256 45.0 0.243 T -70.5 -3.3 45.0 0.243 0.0 LQA
HOH
 8.022
2.871
 CG
O
 N16
O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:181 A:256 33.0 0.178 T -71.9 -9.5 33.0 0.178 0.0 HOH
 4.311
 CE
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:181 A:256 11.0 0.059 T -74.8 -10.9 11.0 0.059 0.0 HOH
 3.043
 N
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:181 A:256 10.0 0.054 T -76.6 -10.2 10.0 0.054 0.0 HOH
 3.012
 N
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 MET A:181 A:256 14.0 0.076 T -63.7 -18.8 14.0 0.076 0.0 L9K
HOH
 6.914
2.734
 CE
O
 N3
O
MET B:181 B:256 16.0 0.086 T -62.3 -19.2 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 MET A:181 A:256 12.0 0.065 T -66.1 -22.9 12.0 0.065 0.0 L9W
HOH
 6.434
2.733
 CE
O
 N3
O
MET B:181 B:256 12.0 0.065 T -66.4 -25.4 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 MET A:181 A:256 15.0 0.081 T -67.6 -17.3 15.0 0.081 0.0 L9W
HOH
 6.521
3.756
 CE
SD
 N3
O
MET B:181 B:256 14.0 0.076 T -68.6 -17.2 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 MET A:181 A:256 13.0 0.07 T -65.0 -20.5 13.0 0.07 0.0 L9W
HOH
 6.663
3.096
 CE
O
 N3
O
MET B:181 B:256 16.0 0.086 T -64.3 -20.8 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 MET A:181 A:256 14.0 0.076 T -64.3 -20.3 14.0 0.076 0.0 L9W
HOH
 6.488
2.752
 CE
O
 N3
O
MET B:181 B:256 15.0 0.081 T -64.4 -19.6 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 MET A:181 A:256 14.0 0.076 T -66.1 -19.7 14.0 0.076 0.0 L9W
HOH
 6.565
3.541
 CE
CE
 N3
O
MET B:181 B:256 15.0 0.081 T -66.2 -19.8 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 MET A:181 A:256 14.0 0.076 T -65.4 -20.6 14.0 0.076 0.0 L9W
HOH
 6.327
2.733
 CE
O
 N3
O
MET B:181 B:256 13.0 0.07 T -65.2 -21.3 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 MET A:182 A:256 30.0 0.162 T -65.6 -23.9 30.0 0.162 0.0 73K
HOH
 8.358
4.120
 SD
SD
 N11
O
MET B:182 B:256 24.0 0.13 T -68.1 -16.3 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:182 A:256 19.0 0.103 T -65.4 -14.1 19.0 0.103 0.0 LQB
HOH
 7.754
3.404
 SD
CE
 C13
O
MET B:182 B:256 13.0 0.07 T -64.0 -9.9 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:182 A:256 21.0 0.114 T -72.0 -10.3 21.0 0.114 0.0 LQD
HOH
 4.143
2.979
 SD
O
 C20
O
MET B:182 B:256 20.0 0.108 T -63.7 -10.3 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:182 A:256 16.0 0.086 T -67.0 -16.8 16.0 0.086 0.0 LQE
HOH
 3.691
3.398
 CE
O
 C17
O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:182 A:256 22.0 0.119 T -68.1 -13.2 22.0 0.119 0.0 LQF
HOH
 6.658
3.510
 CE
CE
 N8
O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:182 A:256 29.0 0.157 T -69.4 -15.2 29.0 0.157 0.0 LQG
HOH
 8.142
2.974
 SD
O
 N2
O
MET B:182 B:256 27.0 0.146 T -69.6 -14.8 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:182 A:256 21.0 0.114 T -64.2 -16.5 21.0 0.114 0.0 LQH
 7.822
 SD
 C9
MET B:182 B:256 19.0 0.103 T -71.7 -20.2 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:182 A:256 15.0 0.081 T -68.0 -18.2 15.0 0.081 0.0 HOH
 3.497
 O
 O
MET C:182 C:256 15.0 0.081 T -67.1 -17.5 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:182 A:256 17.0 0.092 T -62.4 -23.9 17.0 0.092 0.0 7VV
HOH
 3.034
3.245
 CE
N
 H43
O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:182 A:256 23.0 0.124 T -65.4 -15.5 23.0 0.124 0.0 7VY
HOH
 6.564
3.075
 SD
O
 N12
O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:182 A:256 12.0 0.065 T -65.6 -18.4 12.0 0.065 0.0 7W7
HOH
 4.353
2.804
 CE
O
 N19
O
MET B:182 B:256 17.0 0.092 T -66.7 -14.9 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:182 A:256 13.0 0.07 T -67.9 -18.6 13.0 0.07 0.0 7WD
HOH
 3.800
2.966
 CE
N
 N20
O
MET B:182 B:256 18.0 0.097 T -66.9 -18.4 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 MET A:182 A:256 26.0 0.141 T -69.3 -13.3 26.0 0.141 0.0 EJU
HOH
 8.364
3.336
 SD
CE
 N9
O
MET B:182 B:256 24.0 0.13 T -68.5 -17.2 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 MET A:182 A:256 9.0 0.049 T -71.0 -12.6 9.0 0.049 0.0 HOH
 3.724
 SD
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 MET A:182 A:256 11.0 0.059 T -72.6 -17.3 11.0 0.059 0.0 HOH
 3.778
 SD
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 MET B:182 B:256 11.0 0.059 T -67.8 -25.8 0.0 0.0 0.059 A:Q15910:0.059
MET G:182 G:256 12.0 0.065 T -66.5 -27.8 NA NA NA
MET L:182 L:256 13.0 0.07 T -65.0 -25.7 NA NA NA
MET Q:182 R:256 11.0 0.059 T -63.1 -27.0 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 MET B:182 B:256 12.0 0.065 T -76.4 -39.0 0.0 0.0 0.065 A:Q15910:0.065
 74D
 7.748
 CB
 FBI
MET E:182 E:256 11.0 0.059 T -73.5 -34.2 NA NA NA
MET H:182 H:256 12.0 0.065 T -64.5 -32.7 NA NA NA
MET K:182 K:256 12.0 0.065 T -70.2 -22.0 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:184 A:256 12.0 0.065 T -67.3 -17.7 12.0 0.065 0.0 LQD
HOH
 3.311
2.996
 CE
N
 C21
O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:184 A:256 19.0 0.103 T -72.0 -14.2 19.0 0.103 0.0 7XG
HOH
 4.246
3.009
 SD
N
 C22
O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:184 A:256 14.0 0.076 T -68.5 -16.6 14.0 0.076 0.0 82D
HOH
 3.441
3.037
 CE
N
 C28
O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:184 A:256 15.0 0.081 T -68.7 -17.4 15.0 0.081 0.0 82G
HOH
 3.449
3.026
 CE
N
 C23
O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 MET A:180 A:256 11.0 0.059 T -75.3 -11.1 11.0 0.059 0.0 HOH
 2.953
 O
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:187 A:256 19.0 0.103 T -67.7 -15.9 19.0 0.103 0.0 6PU
HOH
 4.504
2.658
 SD
O
 C1
O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 MET A:181 A:256 21.0 0.114 T -62.8 -25.9 21.0 0.114 0.0 GOL
73K
HOH
 4.431
7.350
3.751
 CE
CE
CG
 C3
N11
O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 MET D:181 D:256 30.0 0.162 T -80.5 -1.1 30.0 0.162 0.0
MET E:181 E:256 30.0 0.162 T -78.4 -5.0 30.0 0.162 0.0
MET F:181 F:256 26.0 0.141 T -77.7 -9.6 26.0 0.141 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 MET A:183 A:256 16.0 0.086 T -65.2 -18.3 16.0 0.086 0.0 Q3D
HOH
 6.491
3.012
 CE
O
 O1
O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 MET A:183 A:256 15.0 0.081 T -68.3 -15.3 15.0 0.081 0.0 Q3A
HOH
 6.292
2.822
 CE
O
 N3
O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 MET A:183 A:256 17.0 0.092 T -69.4 -12.8 17.0 0.092 0.0 ZNG
HOH
 6.453
3.097
 CE
N
 N4
O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 MET A:183 A:256 23.0 0.124 T -67.7 -17.1 23.0 0.124 0.0 ZMY
HOH
 6.685
3.792
 CE
CE
 N5
O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:180 A:256 12.0 0.065 T -70.6 -12.8 12.0 0.065 0.0 HOH
 3.476
 O
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:180 A:256 11.0 0.059 T -70.4 -19.9 11.0 0.059 0.0 HOH
 3.198
 O
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:180 A:256 10.0 0.054 T -67.2 -19.0 10.0 0.054 0.0 HOH
 2.708
 O
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:180 A:256 18.0 0.097 T -72.0 -19.4 18.0 0.097 0.0 NDS
HOH
 7.666
3.473
 SD
O
 C1
O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 MET A:176 A:255 31.0 0.168 T -68.3 -8.9 31.0 0.168 0.0 HOH
 3.041
 O
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 MET C:177 E:242 45.0 0.243 T -79.3 -14.2 NA NA NA
MET D:177 F:242 45.0 0.243 T -86.1 -12.8 45.0 0.243 0.0
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 MET C:177 E:242 55.0 0.297 T -79.1 -13.6 55.0 0.297 0.0 6BN
HOH
 6.157
9.911
 CE
N
 C34
O
MET D:177 F:242 56.0 0.303 T -79.1 -13.1 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 MET C:177 E:242 41.0 0.222 T -75.3 -9.9 NA NA NA
MET D:177 F:242 42.0 0.227 T -81.2 -9.5 42.0 0.227 0.0 6BN
 6.930
 CB
 O35
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 MET C:177 E:242 45.0 0.243 T -72.2 -9.1 NA NA NA
MET D:177 F:242 46.0 0.249 T -73.8 -10.6 46.0 0.249 0.0
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 MET A:176 A:256 10.0 0.054 T -73.0 -15.5 10.0 0.054 0.0 HOH
 3.287
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 MET A:256 A:256 41.0 0.222 T -67.2 -20.2