Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 85977233 | . | G | A | CCDS8273.1:NM_003797.3:c.835Gat>Aat_NP_003788.2:p.279D>N | Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6c23 | 4 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | ASP | D:279 | L:279 | 113.0 | 0.753 | T | -99.2 | 37.6 | 113.0 | 0.753 | 0.0 | ||||||
6c24 | 5 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | ASP | E:279 | L:279 | 120.0 | 0.8 | T | -107.2 | 46.7 | 120.0 | 0.8 | 0.0 | ||||||
6wkr | 3 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | C:279 | L:279 | 117.0 | 0.78 | S | -134.3 | 104.2 | 117.0 | 0.78 | 0.0 | ||||||
7kso | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | B:279 | B:279 | 107.0 | 0.713 | T | -86.2 | 7.7 | 107.0 | 0.713 | 0.0 | ||||||
7ksr | 4 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | D:279 | B:279 | 109.0 | 0.727 | T | -86.5 | 12.1 | 109.0 | 0.727 | 0.0 | ||||||
7ktp | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | B:279 | B:279 | 109.0 | 0.727 | T | -84.3 | 7.7 | 109.0 | 0.727 | 0.0 | ||||||
5wg6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2018-06-27 | ASP | B:280 | B:279 | 127.0 | 0.847 | S | -79.5 | 28.9 | 127.0 | 0.847 | 0.0 | ||||||
ASP | D:280 | D:279 | 106.0 | 0.707 | T | -85.1 | -13.3 | NA | NA | NA | |||||||||||||
3jpx | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-10-20 | ASP | A:240 | A:279 | 103.0 | 0.687 | T | -82.3 | -3.3 | 103.0 | 0.687 | 0.0 |
HOH |
2.650 |
OD2 |
O |
||
3jzg | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:240 | A:279 | 98.0 | 0.653 | H | -88.7 | -11.0 | 98.0 | 0.653 | 0.0 |
HOH |
2.236 |
OD1 |
O |
||
3jzh | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:240 | A:279 | 104.0 | 0.693 | T | -83.4 | -0.8 | 104.0 | 0.693 | 0.0 |
HOH |
2.324 |
CB |
O |
||
7kxt | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ASP | A:240 | A:279 | 121.0 | 0.807 | H | -79.5 | -1.8 | 121.0 | 0.807 | 0.0 |
UNX HOH |
9.982 9.952 |
CB N |
UNK O |
||
ASP | B:240 | B:279 | 128.0 | 0.853 | H | -81.3 | -2.0 | NA | NA | NA | |||||||||||||
5wp3 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-09-13 | ASP | A:206 | A:279 | 126.0 | 0.84 | H | -77.4 | -15.9 | 126.0 | 0.84 | 0.0 | ||||||
5h13 | 1 | O75530 | 99.19 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:214 | A:279 | 130.0 | 0.867 | T | -99.9 | 1.1 | 130.0 | 0.867 | 0.0 | ||||||
3jzn | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:204 | A:279 | 112.0 | 0.747 | S | -77.9 | -4.7 | 112.0 | 0.747 | 0.0 |
HOH |
3.248 |
O |
O |
||
3k26 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:204 | A:279 | 101.0 | 0.673 | T | -84.0 | -6.6 | 101.0 | 0.673 | 0.0 |
HOH |
2.339 |
CB |
O |
||
3k27 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:204 | A:279 | 95.0 | 0.633 | T | -83.5 | -2.9 | 95.0 | 0.633 | 0.0 |
HOH |
2.375 |
OD1 |
O |
||
6sfb | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | ASP | A:204 | A:279 | 105.0 | 0.7 | H | -84.3 | -18.4 | 105.0 | 0.7 | 0.0 |
HOH |
2.726 |
OD1 |
O |
||
ASP | B:204 | B:279 | 176.0 | 1.0 | -84.2 | 360.0 | NA | NA | NA | ||||||||||||||
6sfc | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | ASP | A:204 | A:279 | 104.0 | 0.693 | H | -88.9 | -12.5 | 104.0 | 0.693 | 0.0 |
HOH |
2.668 |
OD1 |
O |
||
ASP | B:204 | B:279 | 174.0 | 1.0 | -89.7 | 360.0 | NA | NA | NA | ||||||||||||||
6yvi | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | ASP | A:204 | A:279 | 111.0 | 0.74 | S | -91.1 | -4.7 | 111.0 | 0.74 | 0.0 |
HOH |
3.218 |
OD2 |
O |
||
ASP | B:204 | B:279 | 176.0 | 1.0 | -91.0 | 360.0 | NA | NA | NA | ||||||||||||||
6yvj | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | ASP | A:204 | A:279 | 105.0 | 0.7 | H | -87.4 | -19.6 | 105.0 | 0.7 | 0.0 |
HOH |
2.719 |
OD1 |
O |
||
ASP | B:204 | B:279 | 178.0 | 1.0 | -87.7 | 360.0 | NA | NA | NA | ||||||||||||||
7p3c | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ASP | A:204 | A:279 | 103.0 | 0.687 | H | -85.4 | -17.7 | 103.0 | 0.687 | 0.0 |
HOH |
2.694 |
OD1 |
O |
||
ASP | B:204 | B:279 | 176.0 | 1.0 | -85.9 | 360.0 | NA | NA | NA | ||||||||||||||
7p3g | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ASP | A:204 | A:279 | 101.0 | 0.673 | S | -97.6 | -7.3 | 101.0 | 0.673 | 0.0 |
HOH |
4.111 |
C |
O |
||
ASP | B:204 | B:279 | 171.0 | 1.0 | -99.4 | 360.0 | NA | NA | NA | ||||||||||||||
7p3j | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ASP | A:204 | A:279 | 106.0 | 0.707 | H | -88.2 | -17.3 | 106.0 | 0.707 | 0.0 |
HOH |
2.706 |
OD1 |
O |
||
ASP | B:204 | B:279 | 177.0 | 1.0 | -89.4 | 360.0 | NA | NA | NA | ||||||||||||||
5gsa | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-01 | ASP | A:205 | A:279 | 119.0 | 0.793 | H | -85.7 | -23.3 | 119.0 | 0.793 | 0.0 | ||||||
ASP | B:205 | B:279 | 104.0 | 0.693 | H | -75.7 | -15.4 | NA | NA | NA | |||||||||||||
5h14 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:205 | A:279 | 108.0 | 0.72 | H | -75.6 | -18.2 | 108.0 | 0.72 | 0.0 |
HOH |
3.265 |
OD1 |
O |
||
ASP | B:205 | B:279 | 130.0 | 0.867 | H | -79.8 | -18.2 | NA | NA | NA | |||||||||||||
5h15 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:205 | A:279 | 119.0 | 0.793 | H | -84.6 | -23.3 | 119.0 | 0.793 | 0.0 |
HOH |
4.852 |
OD2 |
O |
||
ASP | B:205 | B:279 | 104.0 | 0.693 | H | -71.4 | -15.0 | NA | NA | NA | |||||||||||||
5h17 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:205 | A:279 | 117.0 | 0.78 | H | -64.2 | -30.4 | 117.0 | 0.78 | 0.0 |
HOH |
5.127 |
OD2 |
O |
||
5h19 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:205 | A:279 | 94.0 | 0.627 | H | -68.7 | -24.2 | 94.0 | 0.627 | 0.0 |
HOH |
4.029 |
CB |
O |
||
5h24 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:205 | A:279 | 111.0 | 0.74 | H | -79.0 | -20.9 | 111.0 | 0.74 | 0.0 | ||||||
ASP | B:205 | B:279 | 109.0 | 0.727 | H | -76.6 | -31.5 | NA | NA | NA | |||||||||||||
5h25 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:205 | A:279 | 97.0 | 0.647 | H | -85.2 | -12.9 | 97.0 | 0.647 | 0.0 | ||||||
ASP | B:205 | B:279 | 113.0 | 0.753 | H | -66.7 | -28.0 | NA | NA | NA | |||||||||||||
5ttw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:205 | A:279 | 104.0 | 0.693 | H | -70.5 | -4.4 | 104.0 | 0.693 | 0.0 |
HOH |
2.957 |
OD1 |
O |
||
ASP | C:205 | C:279 | 98.0 | 0.653 | H | -79.8 | -19.7 | NA | NA | NA | |||||||||||||
5u5h | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:205 | A:279 | 95.0 | 0.633 | H | -83.3 | -5.6 | 95.0 | 0.633 | 0.0 |
HOH |
2.707 |
OD2 |
O |
||
5u5k | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:205 | A:279 | 115.0 | 0.767 | T | -88.3 | 5.1 | 115.0 | 0.767 | 0.0 |
HOH |
4.063 |
C |
O |
||
5u5t | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:205 | A:279 | 136.0 | 0.907 | H | -78.5 | -16.9 | 136.0 | 0.907 | 0.0 |
HOH |
3.431 |
OD2 |
O |
||
ASP | B:205 | B:279 | 135.0 | 0.9 | H | -76.7 | -16.8 | NA | NA | NA | |||||||||||||
5u62 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:205 | A:279 | 136.0 | 0.907 | H | -83.0 | -16.4 | 136.0 | 0.907 | 0.0 |
HOH |
3.534 |
CB |
O |
||
ASP | B:205 | B:279 | 130.0 | 0.867 | H | -75.9 | -16.2 | NA | NA | NA | |||||||||||||
6lo2 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-07-07 | ASP | A:205 | A:279 | 104.0 | 0.693 | H | -80.9 | -5.1 | 104.0 | 0.693 | 0.0 |
HOH |
6.640 |
OD1 |
O |
||
ASP | B:205 | B:279 | 130.0 | 0.867 | T | -93.6 | -17.6 | NA | NA | NA | |||||||||||||
6v3x | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | ASP | A:205 | A:279 | 113.0 | 0.753 | H | -81.2 | -4.5 | 113.0 | 0.753 | 0.0 |
HOH |
3.144 |
O |
O |
||
4x3e | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2015-01-21 | ASP | A:205 | A:279 | 99.0 | 0.66 | T | -83.3 | 7.0 | 99.0 | 0.66 | 0.0 |
HOH |
2.336 |
OD1 |
O |
||
5hyn | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-11 | ASP | B:205 | B:279 | 117.0 | 0.78 | H | -69.2 | -17.2 | 117.0 | 0.78 | 0.0 | ||||||
ASP | G:205 | G:279 | 120.0 | 0.8 | H | -68.8 | -18.4 | NA | NA | NA | |||||||||||||
ASP | L:205 | L:279 | 110.0 | 0.733 | H | -73.7 | -18.7 | NA | NA | NA | |||||||||||||
ASP | Q:205 | R:279 | 103.0 | 0.687 | H | -72.4 | -22.0 | NA | NA | NA | |||||||||||||
5ls6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-22 | ASP | B:205 | B:279 | 119.0 | 0.793 | H | -62.4 | -20.9 | 119.0 | 0.793 | 0.0 | ||||||
ASP | E:205 | E:279 | 112.0 | 0.747 | H | -58.3 | -22.1 | NA | NA | NA | |||||||||||||
ASP | H:205 | H:279 | 104.0 | 0.693 | H | -69.4 | -21.4 | NA | NA | NA | |||||||||||||
ASP | K:205 | K:279 | 110.0 | 0.733 | H | -73.2 | -11.8 | NA | NA | NA | |||||||||||||
5u69 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:207 | A:279 | 104.0 | 0.693 | H | -85.5 | -3.6 | 104.0 | 0.693 | 0.0 |
HOH |
2.639 |
OD1 |
O |
||
5u6d | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:207 | A:279 | 102.0 | 0.68 | H | -83.2 | -3.5 | 102.0 | 0.68 | 0.0 |
HOH |
3.204 |
O |
O |
||
5u8a | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:207 | A:279 | 103.0 | 0.687 | H | -84.2 | -4.7 | 103.0 | 0.687 | 0.0 |
HOH |
2.657 |
OD1 |
O |
||
5u8f | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:207 | A:279 | 95.0 | 0.633 | H | -82.7 | -5.0 | 95.0 | 0.633 | 0.0 |
HOH |
2.686 |
OD1 |
O |
||
3iiw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:203 | A:279 | 106.0 | 0.707 | H | -81.9 | -5.9 | 106.0 | 0.707 | 0.0 |
HOH |
2.469 |
OD1 |
O |
||
5k0m | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:210 | A:279 | 108.0 | 0.72 | H | -85.6 | -6.3 | 108.0 | 0.72 | 0.0 |
HOH |
2.918 |
O |
O |
||
5wuk | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2017-05-03 | ASP | A:204 | A:279 | 106.0 | 0.707 | H | -84.8 | -21.4 | 106.0 | 0.707 | 0.0 |
HOH |
2.790 |
OD2 |
O |
||
6u4y | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2020-07-08 | ASP | D:204 | D:279 | 103.0 | 0.687 | T | -86.8 | 5.2 | 103.0 | 0.687 | 0.0 | ||||||
ASP | E:204 | E:279 | 102.0 | 0.68 | T | -80.4 | 16.4 | 102.0 | 0.68 | 0.0 | |||||||||||||
ASP | F:204 | F:279 | 111.0 | 0.74 | H | -75.3 | -10.3 | 111.0 | 0.74 | 0.0 | |||||||||||||
6w7f | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | ASP | A:206 | A:279 | 104.0 | 0.693 | H | -81.4 | -8.3 | 104.0 | 0.693 | 0.0 |
Q3D HOH |
6.036 2.775 |
OD2 OD2 |
O2 O |
||
6w7g | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | ASP | A:206 | A:279 | 96.0 | 0.64 | H | -81.0 | -5.7 | 96.0 | 0.64 | 0.0 |
Q3A HOH |
5.700 2.653 |
OD2 OD2 |
O1 O |
||
7msb | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | ASP | A:206 | A:279 | 103.0 | 0.687 | H | -82.9 | -3.6 | 103.0 | 0.687 | 0.0 |
HOH |
2.731 |
OD1 |
O |
||
7msd | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | ASP | A:206 | A:279 | 108.0 | 0.72 | H | -80.1 | -5.5 | 108.0 | 0.72 | 0.0 |
HOH |
2.752 |
OD2 |
O |
||
3iiy | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:203 | A:279 | 111.0 | 0.74 | H | -78.0 | -12.8 | 111.0 | 0.74 | 0.0 |
HOH |
3.950 |
CB |
O |
||
3ij0 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:203 | A:279 | 105.0 | 0.7 | H | -85.3 | -4.0 | 105.0 | 0.7 | 0.0 |
HOH |
3.233 |
O |
O |
||
3ij1 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:203 | A:279 | 105.0 | 0.7 | H | -81.7 | -7.4 | 105.0 | 0.7 | 0.0 |
HOH |
2.687 |
OD1 |
O |
||
3ijc | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:203 | A:279 | 105.0 | 0.7 | H | -85.9 | -2.6 | 105.0 | 0.7 | 0.0 |
HOH |
2.992 |
O |
O |
||
2qxv | 1 | Q921E6 | 100.0 | 0.0 |
X-RAY |
2007-08-28 | ASP | A:199 | A:278 | 122.0 | 0.813 | H | -82.4 | -16.7 | 122.0 | 0.813 | 0.0 |
HOH |
2.944 |
CB |
O |
||
4w2r | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | ASP | C:200 | E:265 | 125.0 | 0.833 | H | -83.3 | -29.0 | NA | NA | NA | ||||||
ASP | D:200 | F:265 | 126.0 | 0.84 | H | -78.8 | -30.1 | 126.0 | 0.84 | 0.0 | |||||||||||||
5ij7 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | ASP | C:200 | E:265 | 100.0 | 0.667 | H | -73.4 | -27.1 | 100.0 | 0.667 | 0.0 | ||||||
ASP | D:200 | F:265 | 100.0 | 0.667 | H | -73.3 | -27.3 | NA | NA | NA | |||||||||||||
5ij8 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | ASP | C:200 | E:265 | 132.0 | 0.88 | H | -74.6 | -28.5 | NA | NA | NA | ||||||
ASP | D:200 | F:265 | 133.0 | 0.887 | H | -73.8 | -30.3 | 133.0 | 0.887 | 0.0 | |||||||||||||
6b3w | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | ASP | C:200 | E:265 | 116.0 | 0.773 | H | -71.4 | -36.2 | NA | NA | NA | ||||||
ASP | D:200 | F:265 | 120.0 | 0.8 | H | -73.9 | -28.6 | 120.0 | 0.8 | 0.0 | |||||||||||||
6v3y | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | ASP | A:199 | A:279 | 68.0 | NA | H | -86.7 | -0.3 | 68.0 | NA | NA |
HOH |
3.777 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-o75530-f1 | 1 | O75530 | 100.0 | 0.0 | ASP | A:279 | A:279 | 119.0 | 0.793 | H | -73.7 | -18.8 |