Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85979543 . A C CCDS8273.1:NM_003797.3:c.906agA>agC_NP_003788.2:p.302R>S Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 ARG D:302 L:302 130.0 0.578 -130.1 9.6 83.0 0.369 0.209 K:Q15910:0.209
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 ARG E:302 L:302 159.0 0.707 S -139.3 25.8 159.0 0.707 0.0
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 ARG C:302 L:302 130.0 0.578 -129.4 14.8 44.0 0.196 0.382 E:Q15910:0.382
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 ARG B:302 B:302 165.0 0.733 S -139.0 35.0 165.0 0.733 0.0
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 ARG D:302 B:302 162.0 0.72 S -137.2 44.3 162.0 0.72 0.0
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 ARG B:302 B:302 168.0 0.747 S -137.6 40.2 168.0 0.747 0.0
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 ARG B:303 B:302 133.0 0.591 -128.0 28.4 133.0 0.591 0.0
ARG D:303 D:302 125.0 0.556 -115.6 -5.0 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 ARG A:263 A:302 145.0 0.644 S -117.7 16.7 145.0 0.644 0.0 HOH
 2.902
 N
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:263 A:302 139.0 0.618 -127.0 14.6 139.0 0.618 0.0 HOH
 2.487
 NH1
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:263 A:302 141.0 0.627 S -125.6 15.3 141.0 0.627 0.0 HOH
 2.225
 O
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 ARG A:263 A:302 175.0 0.778 S -119.1 21.9 175.0 0.778 0.0 UNX
UNX
UNX
UNX
HOH
 9.240
2.896
3.658
9.441
3.023
 C
O
O
O
C
 UNK
UNK
UNK
UNK
O
ARG B:263 B:302 172.0 0.764 -118.9 23.4 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 ARG A:229 A:302 65.0 NA S -128.3 14.9 65.0 NA NA UNX
 9.822
 O
 UNK
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 ARG A:237 A:302 175.0 0.778 S -122.3 12.0 175.0 0.778 0.0 HOH
 3.051
 N
 O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:227 A:302 150.0 0.667 S -131.0 19.1 150.0 0.667 0.0 HOH
 3.063
 C
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:227 A:302 140.0 0.622 -122.2 21.6 140.0 0.622 0.0 HOH
 2.360
 NH1
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:227 A:302 148.0 0.658 -123.1 24.0 148.0 0.658 0.0 HOH
 2.694
 NH1
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ARG A:227 A:302 144.0 0.64 -127.6 19.2 144.0 0.64 0.0 HOH
 2.812
 NH1
 O
ARG B:227 B:302 137.0 0.609 -127.2 16.9 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ARG A:227 A:302 133.0 0.591 -126.9 13.3 133.0 0.591 0.0 HOH
 3.007
 N
 O
ARG B:227 B:302 129.0 0.573 S -126.9 12.0 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ARG A:227 A:302 141.0 0.627 S -123.1 16.9 141.0 0.627 0.0 HOH
 2.805
 NH2
 O
ARG B:227 B:302 132.0 0.587 S -122.3 15.3 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ARG A:227 A:302 145.0 0.644 -128.2 15.9 145.0 0.644 0.0 HOH
 2.854
 NH1
 O
ARG B:227 B:302 144.0 0.64 S -127.9 15.0 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:227 A:302 145.0 0.644 -124.8 18.0 145.0 0.644 0.0 HOH
 2.856
 N
 O
ARG B:227 B:302 135.0 0.6 -124.4 17.0 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:227 A:302 137.0 0.609 S -129.0 12.8 137.0 0.609 0.0 HOH
 2.887
 O
 O
ARG B:227 B:302 134.0 0.596 S -128.8 13.0 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:227 A:302 142.0 0.631 S -123.9 14.0 142.0 0.631 0.0 HOH
 3.006
 N
 O
ARG B:227 B:302 136.0 0.604 S -124.1 14.0 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 ARG A:228 A:302 144.0 0.64 S -120.9 9.8 144.0 0.64 0.0 HOH
 2.984
 O
 O
ARG B:228 B:302 158.0 0.702 S -130.0 13.5 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:228 A:302 167.0 0.742 S -124.6 14.3 167.0 0.742 0.0 HOH
 2.883
 N
 O
ARG B:228 B:302 153.0 0.68 S -126.0 14.7 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:228 A:302 172.0 0.764 -135.1 26.9 172.0 0.764 0.0 HOH
 3.168
 C
 O
ARG B:228 B:302 124.0 0.551 S -129.6 12.1 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:228 A:302 146.0 0.649 -129.2 16.5 146.0 0.649 0.0 HOH
 3.054
 N
 O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:228 A:302 166.0 0.738 S -121.7 13.8 166.0 0.738 0.0 HOH
 3.062
 N
 O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:228 A:302 154.0 0.684 S -125.2 15.6 154.0 0.684 0.0 HOH
 2.859
 N
 O
ARG B:228 B:302 108.0 0.48 S -124.8 11.0 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:228 A:302 148.0 0.658 S -134.2 11.0 148.0 0.658 0.0
ARG B:228 B:302 156.0 0.693 -124.9 -10.1 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:228 A:302 146.0 0.649 S -112.1 11.8 146.0 0.649 0.0 UNX
HOH
 3.797
2.798
 CG
NH2
 UNK
O
ARG C:228 C:302 152.0 0.676 S -114.1 15.6 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:228 A:302 134.0 0.596 S -125.1 11.0 134.0 0.596 0.0 HOH
 2.580
 O
 O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:228 A:302 156.0 0.693 S -121.6 13.6 156.0 0.693 0.0 HOH
 2.798
 N
 O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:228 A:302 160.0 0.711 S -124.9 18.7 160.0 0.711 0.0 HOH
 2.735
 O
 O
ARG B:228 B:302 150.0 0.667 S -124.8 18.0 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:228 A:302 90.0 NA S -124.0 16.9 90.0 NA NA HOH
 2.720
 O
 O
ARG B:228 B:302 138.0 0.613 -133.3 21.0 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 ARG A:228 A:302 143.0 0.636 -129.1 24.1 143.0 0.636 0.0 HOH
 3.121
 C
 O
ARG B:228 B:302 137.0 0.609 S -114.7 5.0 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ARG A:228 A:302 141.0 NA S -117.7 23.0 141.0 NA NA HOH
 2.203
 O
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 ARG A:228 A:302 143.0 0.636 -124.0 22.9 143.0 0.636 0.0 HOH
 2.998
 N
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 ARG B:228 B:302 164.0 0.729 S -125.7 17.9 79.0 0.351 0.378 A:Q15910:0.378
ARG G:228 G:302 157.0 0.698 S -125.9 17.5 NA NA NA
ARG L:228 L:302 164.0 0.729 S -125.9 16.4 NA NA NA
ARG Q:228 R:302 165.0 0.733 S -126.0 14.0 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 ARG B:228 B:302 163.0 0.724 -123.3 5.1 75.0 0.333 0.391 A:Q15910:0.391
ARG E:228 E:302 168.0 0.747 -112.1 9.8 NA NA NA
ARG H:228 H:302 166.0 0.738 S -126.3 18.0 NA NA NA
ARG K:228 K:302 171.0 0.76 S -127.1 17.3 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:230 A:302 151.0 0.671 -120.7 20.9 151.0 0.671 0.0 HOH
 2.321
 O
 O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:230 A:302 155.0 0.689 -120.3 19.3 155.0 0.689 0.0 HOH
 2.283
 O
 O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:230 A:302 148.0 0.658 -120.8 19.7 148.0 0.658 0.0 HOH
 2.891
 N
 O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:230 A:302 151.0 0.671 S -120.1 19.0 151.0 0.671 0.0 HOH
 2.288
 O
 O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 ARG A:226 A:302 139.0 0.618 -118.2 23.9 139.0 0.618 0.0 HOH
 2.424
 O
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:233 A:302 148.0 0.658 -120.0 17.5 148.0 0.658 0.0 HOH
 2.323
 O
 O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 ARG A:227 A:302 123.0 0.547 S -130.5 21.6 123.0 0.547 0.0 HOH
 2.992
 N
 O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 ARG D:227 D:302 186.0 0.827 S -107.1 3.3 186.0 0.827 0.0
ARG E:227 E:302 169.0 0.751 S -114.8 7.5 169.0 0.751 0.0
ARG F:227 F:302 191.0 0.849 -124.4 20.4 191.0 0.849 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ARG A:229 A:302 159.0 0.707 -126.0 11.8 159.0 0.707 0.0 HOH
 2.602
 O
 O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ARG A:229 A:302 155.0 0.689 -122.2 17.7 155.0 0.689 0.0 HOH
 2.482
 O
 O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ARG A:229 A:302 156.0 0.693 -123.2 16.1 156.0 0.693 0.0 HOH
 2.474
 O
 O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ARG A:229 A:302 156.0 0.693 -120.0 13.3 156.0 0.693 0.0 HOH
 2.453
 O
 O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:226 A:302 130.0 0.578 -126.1 17.3 130.0 0.578 0.0 HOH
 3.080
 O
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:226 A:302 126.0 0.56 S -119.7 15.5 126.0 0.56 0.0 HOH
 2.887
 N
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:226 A:302 140.0 0.622 -118.6 17.8 140.0 0.622 0.0 HOH
 2.848
 N
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:226 A:302 134.0 0.596 S -115.8 16.4 134.0 0.596 0.0 HOH
 2.962
 N
 O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 ARG A:222 A:294 138.0 0.613 -130.2 18.3 138.0 0.613 0.0 HOH
 2.920
 N
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ARG C:223 E:288 116.0 0.516 S -116.1 15.5 NA NA NA
ARG D:223 F:288 115.0 0.511 S -112.9 23.4 115.0 0.511 0.0
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ARG C:223 E:288 119.0 0.529 S -133.0 7.1 119.0 0.529 0.0 6BN
 9.603
 NH1
 O35
ARG D:223 F:288 116.0 0.516 S -130.3 7.2 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ARG C:223 E:288 107.0 0.476 S -118.0 -4.3 NA NA NA
ARG D:223 F:288 108.0 0.48 S -119.4 -3.6 108.0 0.48 0.0 6BN
 8.910
 NH1
 O35
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ARG C:223 E:288 105.0 0.467 S -121.0 24.7 NA NA NA
ARG D:223 F:288 107.0 0.476 S -119.6 32.0 107.0 0.476 0.0
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ARG A:222 A:302 142.0 0.631 -118.6 19.8 142.0 0.631 0.0 HOH
 2.271
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 ARG A:302 A:302 154.0 0.684 S -125.0 15.1