Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85979577 . T A CCDS8273.1:NM_003797.3:c.940Tgg>Agg_NP_003788.2:p.314W>R Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 TRP D:314 L:314 6.0 0.024 E -87.2 154.6 6.0 0.024 0.0
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 TRP E:314 L:314 5.0 0.02 E -83.8 90.3 5.0 0.02 0.0
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 TRP C:314 L:314 11.0 0.043 E -59.3 140.5 11.0 0.043 0.0
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 TRP B:314 B:314 5.0 0.02 E -99.1 148.9 5.0 0.02 0.0
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 TRP D:314 B:314 3.0 0.012 E -102.3 148.7 3.0 0.012 0.0
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 TRP B:314 B:314 1.0 0.004 E -98.2 152.3 1.0 0.004 0.0
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 TRP B:315 B:314 2.0 0.008 E -69.8 168.8 2.0 0.008 0.0
TRP D:315 D:314 2.0 0.008 E -74.5 118.7 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 TRP A:275 A:314 2.0 0.008 E -63.9 141.2 2.0 0.008 0.0 HOH
 3.396
 O
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 TRP A:275 A:314 3.0 0.012 E -66.7 144.1 3.0 0.012 0.0 HOH
 3.353
 O
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 TRP A:275 A:314 2.0 0.008 E -68.1 142.7 2.0 0.008 0.0 HOH
 3.463
 O
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 TRP A:275 A:314 4.0 0.016 E -75.7 138.1 4.0 0.016 0.0 XB7
UNX
UNX
UNX
UNX
HOH
 6.785
4.718
7.774
2.844
9.826
6.226
 O
O
CE3
O
CH2
CD1
 C12
UNK
UNK
UNK
UNK
O
TRP B:275 B:314 3.0 0.012 E -73.9 138.7 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 TRP A:241 A:314 3.0 0.012 E -86.4 139.3 3.0 0.012 0.0 UNX
 8.588
 CD1
 UNK
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 TRP A:249 A:314 4.0 0.016 E -80.4 145.5 4.0 0.016 0.0 HOH
 2.953
 O
 O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 TRP A:239 A:314 3.0 0.012 E -75.4 140.5 3.0 0.012 0.0 HOH
 3.534
 O
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 TRP A:239 A:314 2.0 0.008 E -73.8 144.2 2.0 0.008 0.0 HOH
 3.328
 O
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 TRP A:239 A:314 2.0 0.008 E -75.1 146.9 2.0 0.008 0.0 HOH
 3.324
 O
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 TRP A:239 A:314 5.0 0.02 E -80.0 146.7 5.0 0.02 0.0 HOH
 2.767
 O
 O
TRP B:239 B:314 5.0 0.02 E -79.4 145.4 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 TRP A:239 A:314 5.0 0.02 E -84.7 147.3 5.0 0.02 0.0 CA
HOH
 8.443
2.795
 CZ3
O
 CA
O
TRP B:239 B:314 4.0 0.016 E -83.5 145.3 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 TRP A:239 A:314 4.0 0.016 E -82.3 146.2 4.0 0.016 0.0 CA
HOH
 9.211
2.738
 CZ3
O
 CA
O
TRP B:239 B:314 4.0 0.016 E -81.2 142.7 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 TRP A:239 A:314 5.0 0.02 E -83.1 145.6 5.0 0.02 0.0 HOH
 2.831
 O
 O
TRP B:239 B:314 6.0 0.024 E -82.3 144.1 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 TRP A:239 A:314 5.0 0.02 E -82.5 145.4 5.0 0.02 0.0 HOH
 2.776
 O
 O
TRP B:239 B:314 4.0 0.016 E -77.7 143.6 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 TRP A:239 A:314 6.0 0.024 E -80.2 148.3 6.0 0.024 0.0 HOH
 2.773
 O
 O
TRP B:239 B:314 5.0 0.02 E -78.7 147.0 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 TRP A:239 A:314 5.0 0.02 E -81.6 146.5 5.0 0.02 0.0 MG
HOH
 9.162
2.739
 CZ3
O
 MG
O
TRP B:239 B:314 5.0 0.02 E -78.9 145.3 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 TRP A:240 A:314 2.0 0.008 E -78.0 147.1 2.0 0.008 0.0 HOH
 2.870
 O
 O
TRP B:240 B:314 2.0 0.008 E -79.0 143.7 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:240 A:314 3.0 0.012 E -78.3 143.0 3.0 0.012 0.0 HOH
 2.886
 O
 O
TRP B:240 B:314 2.0 0.008 E -76.8 146.7 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:240 A:314 2.0 0.008 E -76.2 149.7 2.0 0.008 0.0 HOH
 2.990
 O
 O
TRP B:240 B:314 1.0 0.004 E -78.5 140.0 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:240 A:314 3.0 0.012 E -73.9 145.6 3.0 0.012 0.0 HOH
 3.024
 O
 O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:240 A:314 3.0 0.012 E -74.7 145.9 3.0 0.012 0.0 HOH
 2.688
 O
 O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:240 A:314 2.0 0.008 E -80.5 135.3 2.0 0.008 0.0 HOH
 4.813
 O
 O
TRP B:240 B:314 2.0 0.008 E -93.6 140.1 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:240 A:314 4.0 0.016 E -84.4 146.0 4.0 0.016 0.0
TRP B:240 B:314 3.0 0.012 E -76.0 144.7 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 TRP A:240 A:314 2.0 0.008 E -65.7 143.0 2.0 0.008 0.0 HOH
 3.016
 O
 O
TRP C:240 C:314 11.0 0.043 E -75.9 146.4 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 TRP A:240 A:314 5.0 0.02 E -78.5 143.0 5.0 0.02 0.0 HOH
 2.807
 O
 O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 TRP A:240 A:314 3.0 0.012 E -76.6 143.3 3.0 0.012 0.0 HOH
 3.378
 O
 O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 TRP A:240 A:314 3.0 0.012 E -77.5 143.0 3.0 0.012 0.0 HOH
 2.723
 O
 O
TRP B:240 B:314 3.0 0.012 E -74.5 143.1 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 TRP A:240 A:314 2.0 0.008 E -80.7 140.1 2.0 0.008 0.0 HOH
 2.722
 O
 O
TRP B:240 B:314 3.0 0.012 E -80.6 145.7 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 TRP A:240 A:314 3.0 0.012 E -77.9 143.4 3.0 0.012 0.0 HOH
 2.786
 O
 O
TRP B:240 B:314 4.0 0.016 E -80.3 144.5 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 TRP A:240 A:314 4.0 0.016 E -73.2 141.7 4.0 0.016 0.0 HOH
 3.101
 O
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 TRP A:240 A:314 6.0 0.024 E -76.8 138.9 6.0 0.024 0.0 HOH
 3.021
 O
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 TRP B:240 B:314 1.0 0.004 E -87.5 119.0 1.0 0.004 0.0
TRP G:240 G:314 1.0 0.004 E -89.7 119.6 NA NA NA
TRP L:240 L:314 1.0 0.004 E -88.3 119.6 NA NA NA
TRP Q:240 R:314 1.0 0.004 E -90.3 119.2 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 TRP B:240 B:314 1.0 0.004 E -96.9 108.7 1.0 0.004 0.0
TRP E:240 E:314 2.0 0.008 E -77.8 131.6 NA NA NA
TRP H:240 H:314 2.0 0.008 E -90.3 102.8 NA NA NA
TRP K:240 K:314 1.0 0.004 E -91.6 104.9 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 TRP A:242 A:314 2.0 0.008 E -72.6 143.8 2.0 0.008 0.0 HOH
 3.352
 O
 O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 TRP A:242 A:314 2.0 0.008 E -72.6 143.1 2.0 0.008 0.0 HOH
 3.426
 O
 O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 TRP A:242 A:314 2.0 0.008 E -74.6 143.8 2.0 0.008 0.0 HOH
 3.361
 O
 O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 TRP A:242 A:314 2.0 0.008 E -72.4 144.0 2.0 0.008 0.0 HOH
 3.372
 O
 O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 TRP A:238 A:314 4.0 0.016 E -75.5 140.8 4.0 0.016 0.0 HOH
 3.143
 O
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 TRP A:245 A:314 4.0 0.016 E -75.4 142.0 4.0 0.016 0.0 HOH
 3.447
 O
 O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 TRP A:239 A:314 3.0 0.012 E -78.3 143.9 3.0 0.012 0.0 HOH
 2.917
 O
 O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 TRP D:239 D:314 1.0 0.004 E -79.9 139.5 1.0 0.004 0.0
TRP E:239 E:314 2.0 0.008 E -80.3 144.2 2.0 0.008 0.0
TRP F:239 F:314 1.0 0.004 E -71.3 141.2 1.0 0.004 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 TRP A:241 A:314 6.0 0.024 E -81.7 144.5 6.0 0.024 0.0 HOH
 3.500
 O
 O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 TRP A:241 A:314 5.0 0.02 E -80.2 145.7 5.0 0.02 0.0 HOH
 3.234
 O
 O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 TRP A:241 A:314 6.0 0.024 E -79.5 144.5 6.0 0.024 0.0 HOH
 3.478
 O
 O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 TRP A:241 A:314 6.0 0.024 E -83.1 149.6 6.0 0.024 0.0 HOH
 3.510
 O
 O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 TRP A:238 A:314 3.0 0.012 E -78.2 132.8 3.0 0.012 0.0 HOH
 3.054
 O
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 TRP A:238 A:314 2.0 0.008 E -69.5 140.6 2.0 0.008 0.0 HOH
 3.423
 O
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 TRP A:238 A:314 2.0 0.008 E -70.9 140.0 2.0 0.008 0.0 HOH
 3.360
 O
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 TRP A:238 A:314 3.0 0.012 E -78.4 143.1 3.0 0.012 0.0 HOH
 3.399
 O
 O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 TRP A:234 A:306 2.0 0.008 E -81.4 140.3 2.0 0.008 0.0 HOH
 2.822
 O
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 TRP C:235 E:300 5.0 0.02 E -81.6 139.0 NA NA NA
TRP D:235 F:300 6.0 0.024 E -84.4 135.8 6.0 0.024 0.0
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 TRP C:235 E:300 3.0 0.012 E -73.4 144.7 3.0 0.012 0.0
TRP D:235 F:300 3.0 0.012 E -73.5 145.1 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 TRP C:235 E:300 4.0 0.016 E -80.4 144.6 NA NA NA
TRP D:235 F:300 4.0 0.016 E -81.5 145.0 4.0 0.016 0.0
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 TRP C:235 E:300 9.0 0.035 E -72.5 145.4 NA NA NA
TRP D:235 F:300 10.0 0.039 E -72.6 144.6 10.0 0.039 0.0
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 TRP A:234 A:314 2.0 0.008 E -74.7 141.4 2.0 0.008 0.0 HOH
 3.231
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 TRP A:314 A:314 1.0 0.004 E -80.1 138.7