Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 85988126 | . | T | A | CCDS8273.1:NM_003797.3:c.1071gaT>gaA_NP_003788.2:p.357D>E | Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6c23 | 4 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | ASP | D:357 | L:357 | 72.0 | 0.48 | E | -102.2 | 148.5 | 72.0 | 0.48 | 0.0 | ||||||
| 6c24 | 5 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | ASP | E:357 | L:357 | 85.0 | 0.567 | E | -119.5 | 149.6 | 85.0 | 0.567 | 0.0 | ||||||
| 6wkr | 3 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | C:357 | L:357 | 89.0 | 0.593 | E | -133.8 | 154.8 | 89.0 | 0.593 | 0.0 | ||||||
| 7kso | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | B:357 | B:357 | 129.0 | 0.86 | E | -103.3 | 144.4 | 129.0 | 0.86 | 0.0 | ||||||
| 7ksr | 4 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | D:357 | B:357 | 129.0 | 0.86 | E | -100.9 | 145.2 | 129.0 | 0.86 | 0.0 | ||||||
| 7ktp | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | ASP | B:357 | B:357 | 129.0 | 0.86 | E | -101.8 | 145.8 | 129.0 | 0.86 | 0.0 | ||||||
| 5wg6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2018-06-27 | ASP | B:358 | B:357 | 90.0 | 0.6 | E | -91.2 | 127.6 | 90.0 | 0.6 | 0.0 | ||||||
| ASP | D:358 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3jpx | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-10-20 | ASP | A:318 | A:357 | 87.0 | 0.58 | E | -87.0 | 162.7 | 87.0 | 0.58 | 0.0 |
HOH |
2.672 |
OD2 |
O |
||
| 3jzg | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:318 | A:357 | 88.0 | 0.587 | E | -91.7 | 160.4 | 88.0 | 0.587 | 0.0 |
HOH |
2.644 |
OD2 |
O |
||
| 3jzh | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:318 | A:357 | 85.0 | 0.567 | E | -85.7 | 160.8 | 85.0 | 0.567 | 0.0 |
HOH |
2.706 |
OD2 |
O |
||
| 7kxt | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ASP | A:318 | A:357 | 105.0 | 0.7 | E | -89.4 | 148.0 | 105.0 | 0.7 | 0.0 |
UNX UNX UNX HOH |
8.402 9.047 2.954 3.174 |
OD1 OD2 N OD1 |
UNK UNK UNK O |
||
| ASP | B:318 | B:357 | 112.0 | 0.747 | E | -87.4 | 147.0 | NA | NA | NA | |||||||||||||
| 5wp3 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-09-13 | ASP | A:284 | A:357 | 86.0 | NA | E | -83.1 | 146.3 | 86.0 | NA | NA |
UNX |
9.155 |
CG |
UNK |
||
| 5h13 | 1 | O75530 | 99.19 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:292 | A:357 | 108.0 | 0.72 | E | -93.0 | 150.0 | 108.0 | 0.72 | 0.0 |
GOL HOH |
6.717 2.915 |
OD2 O |
O1 O |
||
| 3jzn | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:282 | A:357 | 86.0 | 0.573 | E | -96.5 | 154.7 | 86.0 | 0.573 | 0.0 |
HOH |
2.637 |
OD2 |
O |
||
| 3k26 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:282 | A:357 | 86.0 | 0.573 | E | -93.3 | 159.6 | 86.0 | 0.573 | 0.0 |
HOH |
2.525 |
OD2 |
O |
||
| 3k27 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | ASP | A:282 | A:357 | 86.0 | 0.573 | E | -88.2 | 157.0 | 86.0 | 0.573 | 0.0 |
HOH |
2.563 |
OD2 |
O |
||
| 6sfb | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | ASP | A:282 | A:357 | 94.0 | 0.627 | E | -90.6 | 145.7 | 94.0 | 0.627 | 0.0 |
HOH |
3.327 |
OD1 |
O |
||
| ASP | B:282 | B:357 | 94.0 | 0.627 | E | -90.0 | 145.3 | NA | NA | NA | |||||||||||||
| 6sfc | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | ASP | A:282 | A:357 | 96.0 | 0.64 | E | -87.2 | 147.6 | 96.0 | 0.64 | 0.0 |
HOH |
3.125 |
OD1 |
O |
||
| ASP | B:282 | B:357 | 91.0 | 0.607 | E | -86.4 | 145.7 | NA | NA | NA | |||||||||||||
| 6yvi | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | ASP | A:282 | A:357 | 103.0 | 0.687 | E | -86.4 | 144.0 | 103.0 | 0.687 | 0.0 |
HOH |
2.795 |
OD2 |
O |
||
| ASP | B:282 | B:357 | 101.0 | 0.673 | E | -71.0 | 144.1 | NA | NA | NA | |||||||||||||
| 6yvj | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | ASP | A:282 | A:357 | 101.0 | 0.673 | E | -89.9 | 146.1 | 101.0 | 0.673 | 0.0 |
HOH |
3.350 |
OD1 |
O |
||
| ASP | B:282 | B:357 | 98.0 | 0.653 | E | -89.8 | 146.3 | NA | NA | NA | |||||||||||||
| 7p3c | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ASP | A:282 | A:357 | 95.0 | 0.633 | E | -91.1 | 149.6 | 95.0 | 0.633 | 0.0 |
HOH |
2.800 |
OD2 |
O |
||
| ASP | B:282 | B:357 | 89.0 | 0.593 | E | -89.8 | 147.5 | NA | NA | NA | |||||||||||||
| 7p3g | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ASP | A:282 | A:357 | 94.0 | 0.627 | E | -85.8 | 145.4 | 94.0 | 0.627 | 0.0 |
HOH |
3.056 |
OD2 |
O |
||
| ASP | B:282 | B:357 | 97.0 | 0.647 | E | -85.9 | 144.7 | NA | NA | NA | |||||||||||||
| 7p3j | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | ASP | A:282 | A:357 | 104.0 | 0.693 | E | -92.2 | 148.0 | 104.0 | 0.693 | 0.0 |
HOH |
2.807 |
N |
O |
||
| ASP | B:282 | B:357 | 99.0 | 0.66 | E | -91.3 | 147.6 | NA | NA | NA | |||||||||||||
| 5gsa | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-01 | ASP | A:283 | A:357 | 76.0 | 0.507 | E | -86.2 | 146.6 | 76.0 | 0.507 | 0.0 |
HOH |
8.217 |
OD1 |
O |
||
| ASP | B:283 | B:357 | 69.0 | 0.46 | E | -88.3 | 146.1 | NA | NA | NA | |||||||||||||
| 5h14 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:283 | A:357 | 89.0 | 0.593 | E | -86.3 | 144.8 | 89.0 | 0.593 | 0.0 |
HOH |
3.506 |
N |
O |
||
| ASP | B:283 | B:357 | 63.0 | 0.42 | E | -85.0 | 146.0 | NA | NA | NA | |||||||||||||
| 5h15 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:283 | A:357 | 88.0 | 0.587 | E | -83.9 | 149.5 | 88.0 | 0.587 | 0.0 |
HOH |
3.058 |
OD2 |
O |
||
| ASP | B:283 | B:357 | 104.0 | 0.693 | E | -87.1 | 146.6 | NA | NA | NA | |||||||||||||
| 5h17 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:283 | A:357 | 82.0 | 0.547 | E | -89.5 | 148.1 | 82.0 | 0.547 | 0.0 |
HOH |
3.296 |
N |
O |
||
| 5h19 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:283 | A:357 | 112.0 | 0.747 | E | -88.8 | 143.9 | 112.0 | 0.747 | 0.0 |
HOH |
2.685 |
O |
O |
||
| 5h24 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:283 | A:357 | 65.0 | 0.433 | E | -87.1 | 148.6 | 65.0 | 0.433 | 0.0 |
HOH |
2.717 |
OD1 |
O |
||
| ASP | B:283 | B:357 | 72.0 | 0.48 | E | -81.4 | 146.0 | NA | NA | NA | |||||||||||||
| 5h25 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:283 | A:357 | 73.0 | 0.487 | E | -78.6 | 143.4 | 73.0 | 0.487 | 0.0 | ||||||
| ASP | B:283 | B:357 | 88.0 | 0.587 | E | -80.9 | 142.5 | NA | NA | NA | |||||||||||||
| 5ttw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:283 | A:357 | 92.0 | 0.613 | E | -93.8 | 151.2 | 92.0 | 0.613 | 0.0 |
UNX HOH |
6.658 2.638 |
O O |
UNK O |
||
| ASP | C:283 | C:357 | 89.0 | 0.593 | E | -99.9 | 143.6 | NA | NA | NA | |||||||||||||
| 5u5h | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:283 | A:357 | 113.0 | 0.753 | E | -92.7 | 147.0 | 113.0 | 0.753 | 0.0 |
HOH |
2.715 |
OD1 |
O |
||
| 5u5k | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:283 | A:357 | 117.0 | 0.78 | E | -83.9 | 143.4 | 117.0 | 0.78 | 0.0 |
HOH |
3.048 |
O |
O |
||
| 5u5t | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:283 | A:357 | 114.0 | 0.76 | E | -90.5 | 142.3 | 114.0 | 0.76 | 0.0 |
HOH |
2.738 |
O |
O |
||
| ASP | B:283 | B:357 | 115.0 | 0.767 | E | -88.0 | 142.5 | NA | NA | NA | |||||||||||||
| 5u62 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:283 | A:357 | 116.0 | 0.773 | E | -87.1 | 142.9 | 116.0 | 0.773 | 0.0 |
GOL HOH |
8.191 2.742 |
C O |
O3 O |
||
| ASP | B:283 | B:357 | 108.0 | 0.72 | E | -84.0 | 146.2 | NA | NA | NA | |||||||||||||
| 6lo2 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-07-07 | ASP | A:283 | A:357 | 77.0 | 0.513 | E | -82.4 | 149.4 | 77.0 | 0.513 | 0.0 |
HOH |
2.711 |
OD2 |
O |
||
| ASP | B:283 | B:357 | 74.0 | 0.493 | E | -92.0 | 140.7 | NA | NA | NA | |||||||||||||
| 6v3x | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | ASP | A:283 | A:357 | 85.0 | 0.567 | E | -87.8 | 158.0 | 85.0 | 0.567 | 0.0 |
HOH |
2.701 |
OD2 |
O |
||
| 4x3e | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2015-01-21 | ASP | A:283 | A:357 | 93.0 | 0.62 | E | -92.9 | 147.1 | 93.0 | 0.62 | 0.0 |
HOH |
3.361 |
OD1 |
O |
||
| 5hyn | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-11 | ASP | B:283 | B:357 | 80.0 | 0.533 | E | -74.4 | 147.3 | 80.0 | 0.533 | 0.0 | ||||||
| ASP | G:283 | G:357 | 83.0 | 0.553 | E | -76.4 | 149.0 | NA | NA | NA | |||||||||||||
| ASP | L:283 | L:357 | 105.0 | 0.7 | E | -72.1 | 146.0 | NA | NA | NA | |||||||||||||
| ASP | Q:283 | R:357 | 85.0 | 0.567 | E | -77.9 | 145.8 | NA | NA | NA | |||||||||||||
| 5ls6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-22 | ASP | B:283 | B:357 | 90.0 | 0.6 | -56.7 | 134.2 | 90.0 | 0.6 | 0.0 | |||||||
| ASP | E:283 | E:357 | 80.0 | 0.533 | E | -66.5 | 142.4 | NA | NA | NA | |||||||||||||
| ASP | H:283 | H:357 | 96.0 | 0.64 | E | -72.4 | 151.3 | NA | NA | NA | |||||||||||||
| ASP | K:283 | K:357 | 85.0 | 0.567 | E | -92.0 | 131.3 | NA | NA | NA | |||||||||||||
| 5u69 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:285 | A:357 | 85.0 | 0.567 | E | -90.7 | 157.9 | 85.0 | 0.567 | 0.0 |
HOH |
2.669 |
OD2 |
O |
||
| 5u6d | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:285 | A:357 | 83.0 | 0.553 | E | -89.5 | 159.9 | 83.0 | 0.553 | 0.0 |
HOH |
3.107 |
OD1 |
O |
||
| 5u8a | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:285 | A:357 | 84.0 | 0.56 | E | -90.8 | 159.1 | 84.0 | 0.56 | 0.0 |
HOH |
2.632 |
OD2 |
O |
||
| 5u8f | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | ASP | A:285 | A:357 | 85.0 | 0.567 | E | -90.1 | 157.6 | 85.0 | 0.567 | 0.0 |
HOH |
2.658 |
OD2 |
O |
||
| 3iiw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:281 | A:357 | 86.0 | 0.573 | E | -87.6 | 157.1 | 86.0 | 0.573 | 0.0 |
HOH |
2.514 |
OD2 |
O |
||
| 5k0m | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | ASP | A:288 | A:357 | 85.0 | 0.567 | E | -91.1 | 158.3 | 85.0 | 0.567 | 0.0 |
HOH |
2.618 |
OD2 |
O |
||
| 5wuk | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2017-05-03 | ASP | A:282 | A:357 | 61.0 | 0.407 | E | -92.6 | 150.8 | 61.0 | 0.407 | 0.0 |
HOH |
2.664 |
OD1 |
O |
||
| 6u4y | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2020-07-08 | ASP | D:282 | D:357 | 109.0 | 0.727 | E | -92.9 | 146.3 | 100.0 | 0.667 | 0.06 |
B:Q15910:0.06 |
|||||
| ASP | E:282 | E:357 | 108.0 | 0.72 | E | -94.7 | 142.9 | 107.0 | 0.713 | 0.007 |
C:Q15910:0.007 |
||||||||||||
| ASP | F:282 | F:357 | 109.0 | 0.727 | E | -92.2 | 134.6 | 109.0 | 0.727 | 0.0 | |||||||||||||
| 6w7f | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | ASP | A:284 | A:357 | 88.0 | 0.587 | E | -83.1 | 153.6 | 88.0 | 0.587 | 0.0 |
HOH |
2.693 |
OD2 |
O |
||
| 6w7g | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | ASP | A:284 | A:357 | 85.0 | 0.567 | E | -87.9 | 156.6 | 85.0 | 0.567 | 0.0 |
HOH |
2.615 |
OD2 |
O |
||
| 7msb | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | ASP | A:284 | A:357 | 83.0 | 0.553 | E | -88.2 | 158.4 | 83.0 | 0.553 | 0.0 |
HOH |
2.642 |
OD2 |
O |
||
| 7msd | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | ASP | A:284 | A:357 | 85.0 | 0.567 | E | -82.9 | 154.8 | 85.0 | 0.567 | 0.0 |
HOH |
2.657 |
OD1 |
O |
||
| 3iiy | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:281 | A:357 | 87.0 | 0.58 | E | -87.8 | 156.7 | 87.0 | 0.58 | 0.0 |
HOH |
2.675 |
OD1 |
O |
||
| 3ij0 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:281 | A:357 | 87.0 | 0.58 | E | -90.0 | 156.8 | 87.0 | 0.58 | 0.0 |
HOH |
2.926 |
OD1 |
O |
||
| 3ij1 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:281 | A:357 | 87.0 | 0.58 | E | -85.0 | 155.0 | 87.0 | 0.58 | 0.0 |
HOH |
2.584 |
OD2 |
O |
||
| 3ijc | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | ASP | A:281 | A:357 | 85.0 | 0.567 | E | -87.0 | 156.9 | 85.0 | 0.567 | 0.0 |
HOH |
2.892 |
O |
O |
||
| 2qxv | 1 | Q921E6 | 100.0 | 0.0 |
X-RAY |
2007-08-28 | ASP | A:277 | A:349 | 80.0 | 0.533 | E | -85.6 | 149.8 | 80.0 | 0.533 | 0.0 |
HOH |
2.596 |
O |
O |
||
| 4w2r | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | ASP | C:278 | E:343 | 97.0 | 0.647 | E | -92.9 | 144.3 | NA | NA | NA | ||||||
| ASP | D:278 | F:343 | 96.0 | 0.64 | E | -102.0 | 148.3 | 96.0 | 0.64 | 0.0 | |||||||||||||
| 5ij7 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | ASP | C:278 | E:343 | 88.0 | 0.587 | E | -90.1 | 151.3 | 88.0 | 0.587 | 0.0 |
HOH |
8.300 |
C |
O |
||
| ASP | D:278 | F:343 | 78.0 | 0.52 | E | -90.9 | 151.8 | NA | NA | NA | |||||||||||||
| 5ij8 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | ASP | C:278 | E:343 | 82.0 | 0.547 | E | -98.2 | 137.5 | NA | NA | NA | ||||||
| ASP | D:278 | F:343 | 83.0 | 0.553 | E | -98.2 | 136.8 | 83.0 | 0.553 | 0.0 | |||||||||||||
| 6b3w | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | ASP | C:278 | E:343 | 105.0 | 0.7 | E | -100.7 | 147.2 | NA | NA | NA | ||||||
| ASP | D:278 | F:343 | 104.0 | 0.693 | E | -101.8 | 148.1 | 104.0 | 0.693 | 0.0 | |||||||||||||
| 6v3y | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | ASP | A:277 | A:357 | 85.0 | 0.567 | E | -87.8 | 157.0 | 85.0 | 0.567 | 0.0 |
HOH |
2.555 |
OD2 |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o75530-f1 | 1 | O75530 | 100.0 | 0.0 | ASP | A:357 | A:357 | 104.0 | 0.693 | E | -81.7 | 142.8 | |