Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85988152 . T A CCDS8273.1:NM_003797.3:c.1097aTg>aAg_NP_003788.2:p.366M>K Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 MET D:366 L:366 1.0 0.005 -132.6 93.0 1.0 0.005 0.0
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 MET E:366 L:366 3.0 0.016 -141.6 83.4 3.0 0.016 0.0
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 MET C:366 L:366 5.0 0.027 -139.7 130.1 5.0 0.027 0.0
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 MET B:366 B:366 1.0 0.005 -118.6 149.5 1.0 0.005 0.0
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 MET D:366 B:366 2.0 0.011 -117.1 150.0 2.0 0.011 0.0
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 MET B:366 B:366 1.0 0.005 -117.7 149.3 1.0 0.005 0.0
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 MET B:367 B:366 0.0 0.0 -141.2 94.2 0.0 0.0 0.0
MET D:367 D:366 24.0 0.13 -85.8 147.0 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 MET A:327 A:366 0.0 0.0 -139.4 109.1 0.0 0.0 0.0 HOH
 3.229
 CB
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:327 A:366 0.0 0.0 -139.8 104.8 0.0 0.0 0.0 HOH
 3.387
 CB
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:327 A:366 0.0 0.0 -137.6 108.9 0.0 0.0 0.0 HOH
 3.198
 CB
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 MET A:327 A:366 0.0 0.0 -120.8 118.4 0.0 0.0 0.0 UNX
UNX
UNX
HOH
 8.957
8.282
8.066
4.201
 N
CG
CG
CA
 UNK
UNK
UNK
O
MET B:327 B:366 0.0 0.0 -120.7 118.0 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 MET A:293 A:366 1.0 0.005 -116.5 104.7 1.0 0.005 0.0 UNX
 8.241
 N
 UNK
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 MET A:301 A:366 1.0 0.005 -130.4 113.8 1.0 0.005 0.0 LQA
HOH
 4.445
4.850
 N
C
 C25
O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:291 A:366 0.0 0.0 -123.5 112.5 0.0 0.0 0.0 HOH
 5.048
 C
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:291 A:366 0.0 0.0 -130.6 112.7 0.0 0.0 0.0 HOH
 3.293
 CB
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 MET A:291 A:366 0.0 0.0 -133.4 111.4 0.0 0.0 0.0 HOH
 3.285
 CB
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 MET A:291 A:366 1.0 0.005 -133.8 120.1 1.0 0.005 0.0 L9K
HOH
 4.115
3.819
 N
CB
 O2
O
MET B:291 B:366 1.0 0.005 -133.5 119.5 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 MET A:291 A:366 1.0 0.005 -132.9 115.3 1.0 0.005 0.0 L9W
HOH
 3.225
3.723
 N
CB
 O2
O
MET B:291 B:366 0.0 0.0 -134.2 117.6 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 MET A:291 A:366 0.0 0.0 -134.1 112.3 0.0 0.0 0.0 L9W
HOH
 3.335
3.991
 N
CB
 O2
O
MET B:291 B:366 0.0 0.0 -134.0 109.5 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 MET A:291 A:366 0.0 0.0 -136.1 117.9 0.0 0.0 0.0 L9W
HOH
 3.227
3.812
 N
CB
 O2
O
MET B:291 B:366 1.0 0.005 -136.8 116.3 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 MET A:291 A:366 0.0 0.0 -138.7 118.6 0.0 0.0 0.0 L9W
HOH
 3.170
3.815
 N
CB
 O2
O
MET B:291 B:366 1.0 0.005 -137.1 121.0 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 MET A:291 A:366 1.0 0.005 -140.8 114.0 1.0 0.005 0.0 L9W
HOH
 3.252
3.946
 N
CB
 O2
O
MET B:291 B:366 0.0 0.0 -140.3 119.3 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 MET A:291 A:366 0.0 0.0 -134.7 119.0 0.0 0.0 0.0 L9W
HOH
 3.291
3.871
 N
CB
 O2
O
MET B:291 B:366 1.0 0.005 -133.6 115.1 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 MET A:292 A:366 0.0 0.0 -131.1 103.3 0.0 0.0 0.0 73K
HOH
 4.468
4.219
 N
N
 C16
O
MET B:292 B:366 0.0 0.0 -127.6 113.0 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:292 A:366 0.0 0.0 -130.9 121.2 0.0 0.0 0.0 LQB
HOH
 4.108
4.926
 N
C
 C26
O
MET B:292 B:366 0.0 0.0 -127.0 117.9 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:292 A:366 0.0 0.0 -128.9 117.9 0.0 0.0 0.0 LQD
HOH
 3.888
3.941
 N
CB
 C22
O
MET B:292 B:366 1.0 0.005 -132.7 119.9 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:292 A:366 1.0 0.005 -132.6 114.5 1.0 0.005 0.0 LQE
HOH
 3.636
3.980
 N
CG
 O25
O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:292 A:366 0.0 0.0 -124.6 115.3 0.0 0.0 0.0 LQF
HOH
 4.408
4.060
 N
CB
 C19
O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:292 A:366 0.0 0.0 -133.6 111.5 0.0 0.0 0.0 LQG
HOH
 4.391
4.339
 N
CB
 C11
O
MET B:292 B:366 0.0 0.0 -120.0 112.7 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:292 A:366 0.0 0.0 -100.4 116.8 0.0 0.0 0.0 LQH
HOH
 6.448
4.638
 N
C
 C17
O
MET B:292 B:366 0.0 0.0 -115.6 118.3 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:292 A:366 0.0 0.0 -138.6 111.2 0.0 0.0 0.0 UNX
UNX
HOH
 7.680
9.597
3.350
 N
C
CB
 UNK
UNK
O
MET C:292 C:366 0.0 0.0 -136.8 109.1 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:292 A:366 1.0 0.005 -131.3 121.0 1.0 0.005 0.0 7VV
HOH
 3.435
3.774
 N
CB
 O22
O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:292 A:366 0.0 0.0 -132.8 116.2 0.0 0.0 0.0 7VY
HOH
 3.637
4.711
 N
C
 O14
O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:292 A:366 0.0 0.0 -131.9 116.4 0.0 0.0 0.0 7W7
HOH
 3.619
3.845
 N
CB
 O7
O
MET B:292 B:366 0.0 0.0 -134.4 116.2 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 MET A:292 A:366 0.0 0.0 -131.3 118.3 0.0 0.0 0.0 7WD
HOH
 3.531
3.920
 N
CB
 O7
O
MET B:292 B:366 1.0 0.005 -132.9 115.6 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 MET A:292 A:366 1.0 0.005 -131.6 120.1 1.0 0.005 0.0 EJU
HOH
 3.782
4.210
 N
CG
 C21
O
MET B:292 B:366 1.0 0.005 -134.7 112.9 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 MET A:292 A:366 0.0 0.0 -129.6 113.6 0.0 0.0 0.0 HOH
 3.228
 CB
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 MET A:292 A:366 0.0 0.0 -125.2 116.6 0.0 0.0 0.0 HOH
 3.821
 CB
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 MET B:292 B:366 0.0 0.0 -113.6 109.3 0.0 0.0 0.0
MET G:292 G:366 0.0 0.0 -115.8 107.2 NA NA NA
MET L:292 L:366 0.0 0.0 -112.0 106.7 NA NA NA
MET Q:292 R:366 0.0 0.0 -113.7 105.6 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 MET B:292 B:366 0.0 0.0 -122.5 106.6 0.0 0.0 0.0
MET E:292 E:366 0.0 0.0 -91.8 105.3 NA NA NA
MET H:292 H:366 0.0 0.0 -128.2 94.7 NA NA NA
MET K:292 K:366 0.0 0.0 -129.0 87.8 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:294 A:366 0.0 0.0 -133.1 122.0 0.0 0.0 0.0 LQD
HOH
 3.894
3.721
 N
CB
 C22
O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:294 A:366 0.0 0.0 -133.5 126.3 0.0 0.0 0.0 7XG
HOH
 3.755
3.723
 N
CG
 C6
O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:294 A:366 0.0 0.0 -134.4 124.5 0.0 0.0 0.0 82D
HOH
 3.782
3.718
 N
CG
 C19
O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 MET A:294 A:366 0.0 0.0 -134.3 126.7 0.0 0.0 0.0 82G
HOH
 3.825
3.753
 N
CG
 C5
O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 MET A:290 A:366 0.0 0.0 -134.2 109.1 0.0 0.0 0.0 HOH
 3.335
 CB
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 MET A:297 A:366 0.0 0.0 -132.8 126.5 0.0 0.0 0.0 6PU
HOH
 3.801
3.678
 N
CG
 C21
O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 MET A:291 A:366 0.0 0.0 -135.6 110.1 0.0 0.0 0.0 73K
HOH
 4.342
4.023
 N
CB
 C15
O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 MET D:291 D:366 0.0 0.0 -117.9 119.8 0.0 0.0 0.0
MET E:291 E:366 0.0 0.0 -128.6 114.2 0.0 0.0 0.0
MET F:291 F:366 0.0 0.0 -118.8 109.1 0.0 0.0 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 MET A:293 A:366 1.0 0.005 -135.2 124.8 1.0 0.005 0.0 Q3D
HOH
 3.240
3.705
 N
CB
 O
O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 MET A:293 A:366 0.0 0.0 -136.0 125.3 0.0 0.0 0.0 Q3A
HOH
 3.196
3.744
 N
CG
 O
O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 MET A:293 A:366 0.0 0.0 -139.4 122.1 0.0 0.0 0.0 ZNG
HOH
 3.122
3.751
 N
CG
 O1
O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 MET A:293 A:366 5.0 0.027 -134.1 139.4 5.0 0.027 0.0 ZMY
HOH
 2.860
5.128
 O
C
 H17
O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:290 A:366 0.0 0.0 -133.8 103.7 0.0 0.0 0.0 HOH
 4.019
 CB
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:290 A:366 0.0 0.0 -132.7 106.4 0.0 0.0 0.0 HOH
 3.768
 CB
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:290 A:366 0.0 0.0 -134.2 111.8 0.0 0.0 0.0 HOH
 3.301
 CB
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 MET A:290 A:366 0.0 0.0 -128.0 109.1 0.0 0.0 0.0 NDS
HOH
 6.591
3.750
 SD
CB
 O3
O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 MET A:286 A:358 0.0 0.0 -116.6 109.3 0.0 0.0 0.0 HOH
 3.980
 CB
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 MET C:287 E:352 0.0 0.0 -127.7 111.8 NA NA NA
MET D:287 F:352 0.0 0.0 -130.1 119.2 0.0 0.0 0.0
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 MET C:287 E:352 0.0 0.0 -125.1 113.0 0.0 0.0 0.0 HOH
 6.454
 CB
 O
MET D:287 F:352 0.0 0.0 -125.0 114.2 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 MET C:287 E:352 0.0 0.0 -126.1 108.9 NA NA NA
MET D:287 F:352 0.0 0.0 -126.3 109.3 0.0 0.0 0.0
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 MET C:287 E:352 1.0 0.005 -125.8 107.9 NA NA NA
MET D:287 F:352 0.0 0.0 -130.1 110.9 0.0 0.0 0.0
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 MET A:286 A:366 0.0 0.0 -132.8 112.6 0.0 0.0 0.0 HOH
 3.272
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 MET A:366 A:366 0.0 0.0 -120.2 108.0