Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 85988960 | . | A | C | CCDS8273.1:NM_003797.3:c.1126Atg>Ctg_NP_003788.2:p.376M>L | Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6c23 | 4 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | MET | D:376 | L:376 | 5.0 | 0.027 | E | -146.8 | 158.6 | 5.0 | 0.027 | 0.0 | ||||||
| 6c24 | 5 | O75530 | 100.0 | 0.0 |
EM |
2018-01-24 | MET | E:376 | L:376 | 0.0 | 0.0 | E | -137.6 | 146.4 | 0.0 | 0.0 | 0.0 | ||||||
| 6wkr | 3 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | MET | C:376 | L:376 | 14.0 | 0.076 | E | -133.9 | 163.2 | 14.0 | 0.076 | 0.0 | ||||||
| 7kso | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | MET | B:376 | B:376 | 1.0 | 0.005 | E | -151.6 | -173.3 | 1.0 | 0.005 | 0.0 | ||||||
| 7ksr | 4 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | MET | D:376 | B:376 | 0.0 | 0.0 | E | -151.2 | -174.1 | 0.0 | 0.0 | 0.0 | ||||||
| 7ktp | 2 | O75530 | 100.0 | 0.0 |
EM |
2021-02-03 | MET | B:376 | B:376 | 1.0 | 0.005 | E | -151.4 | -173.6 | 1.0 | 0.005 | 0.0 | ||||||
| 5wg6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2018-06-27 | MET | B:377 | B:376 | 5.0 | 0.027 | E | -105.2 | 152.1 | 5.0 | 0.027 | 0.0 | ||||||
| MET | D:377 | D:376 | 36.0 | 0.195 | -76.6 | 360.0 | NA | NA | NA | ||||||||||||||
| 3jpx | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-10-20 | MET | A:337 | A:376 | 13.0 | 0.07 | E | -140.4 | 168.9 | 13.0 | 0.07 | 0.0 |
HOH |
3.898 |
CE |
O |
||
| 3jzg | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | MET | A:337 | A:376 | 13.0 | 0.07 | E | -150.3 | 166.9 | 13.0 | 0.07 | 0.0 |
HOH |
3.386 |
CE |
O |
||
| 3jzh | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | MET | A:337 | A:376 | 17.0 | 0.092 | E | -150.0 | 166.5 | 17.0 | 0.092 | 0.0 |
HOH |
3.418 |
CE |
O |
||
| 7kxt | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | MET | A:337 | A:376 | 0.0 | 0.0 | E | -139.8 | 146.4 | 0.0 | 0.0 | 0.0 |
XB7 UNX UNX HOH |
8.862 7.364 9.350 6.258 |
N O O CE |
C4 UNK UNK O |
||
| MET | B:337 | B:376 | 17.0 | 0.092 | E | -141.2 | 145.5 | NA | NA | NA | |||||||||||||
| 5wp3 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-09-13 | MET | A:303 | A:376 | 2.0 | 0.011 | E | -123.0 | 139.6 | 2.0 | 0.011 | 0.0 | ||||||
| 5h13 | 1 | O75530 | 99.19 | 0.0 |
X-RAY |
2017-01-25 | MET | A:311 | A:376 | 0.0 | 0.0 | E | -129.2 | 145.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.403 |
N |
O |
||
| 3jzn | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | MET | A:301 | A:376 | 13.0 | 0.07 | E | -145.2 | 160.1 | 13.0 | 0.07 | 0.0 |
HOH |
4.407 |
SD |
O |
||
| 3k26 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | MET | A:301 | A:376 | 17.0 | 0.092 | E | -146.7 | 161.5 | 17.0 | 0.092 | 0.0 |
HOH |
3.547 |
CE |
O |
||
| 3k27 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-12-15 | MET | A:301 | A:376 | 1.0 | 0.005 | E | -145.4 | 164.6 | 1.0 | 0.005 | 0.0 |
HOH |
3.682 |
CE |
O |
||
| 6sfb | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | MET | A:301 | A:376 | 24.0 | 0.13 | E | -132.5 | 146.9 | 24.0 | 0.13 | 0.0 |
HOH |
5.119 |
CE |
O |
||
| MET | B:301 | B:376 | 27.0 | 0.146 | E | -134.7 | 143.3 | NA | NA | NA | |||||||||||||
| 6sfc | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2019-09-25 | MET | A:301 | A:376 | 20.0 | 0.108 | E | -125.4 | 142.7 | 20.0 | 0.108 | 0.0 |
HOH |
6.755 |
O |
O |
||
| MET | B:301 | B:376 | 26.0 | 0.141 | E | -140.3 | 146.0 | NA | NA | NA | |||||||||||||
| 6yvi | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | MET | A:301 | A:376 | 16.0 | 0.086 | E | -133.9 | 145.3 | 16.0 | 0.086 | 0.0 |
HOH |
3.940 |
CE |
O |
||
| MET | B:301 | B:376 | 30.0 | 0.162 | E | -134.1 | 146.8 | NA | NA | NA | |||||||||||||
| 6yvj | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-12 | MET | A:301 | A:376 | 18.0 | 0.097 | E | -128.4 | 145.1 | 18.0 | 0.097 | 0.0 |
HOH |
3.233 |
SD |
O |
||
| MET | B:301 | B:376 | 27.0 | 0.146 | E | -136.3 | 148.7 | NA | NA | NA | |||||||||||||
| 7p3c | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | MET | A:301 | A:376 | 28.0 | 0.151 | E | -135.9 | 146.6 | 28.0 | 0.151 | 0.0 |
HOH |
3.860 |
CG |
O |
||
| MET | B:301 | B:376 | 28.0 | 0.151 | E | -134.8 | 146.2 | NA | NA | NA | |||||||||||||
| 7p3g | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | MET | A:301 | A:376 | 22.0 | 0.119 | E | -135.2 | 142.7 | 22.0 | 0.119 | 0.0 |
HOH |
6.415 |
CE |
O |
||
| MET | B:301 | B:376 | 29.0 | 0.157 | E | -137.2 | 150.2 | NA | NA | NA | |||||||||||||
| 7p3j | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-12-08 | MET | A:301 | A:376 | 18.0 | 0.097 | E | -132.2 | 144.8 | 18.0 | 0.097 | 0.0 |
HOH |
3.374 |
CE |
O |
||
| MET | B:301 | B:376 | 29.0 | 0.157 | E | -132.2 | 144.2 | NA | NA | NA | |||||||||||||
| 5gsa | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-01 | MET | A:302 | A:376 | 1.0 | 0.005 | E | -119.9 | 145.8 | 1.0 | 0.005 | 0.0 |
HOH |
7.121 |
O |
O |
||
| MET | B:302 | B:376 | 1.0 | 0.005 | E | -132.4 | 138.8 | NA | NA | NA | |||||||||||||
| 5h14 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -133.2 | 143.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.710 |
CE |
O |
||
| MET | B:302 | B:376 | 0.0 | 0.0 | E | -130.4 | 139.7 | NA | NA | NA | |||||||||||||
| 5h15 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:302 | A:376 | 1.0 | 0.005 | E | -128.2 | 144.0 | 1.0 | 0.005 | 0.0 |
HOH |
5.896 |
CE |
O |
||
| MET | B:302 | B:376 | 0.0 | 0.0 | E | -125.5 | 141.0 | NA | NA | NA | |||||||||||||
| 5h17 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:302 | A:376 | 1.0 | 0.005 | E | -127.5 | 150.2 | 1.0 | 0.005 | 0.0 |
HOH |
6.809 |
CE |
O |
||
| 5h19 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:302 | A:376 | 2.0 | 0.011 | E | -128.5 | 141.9 | 2.0 | 0.011 | 0.0 |
HOH |
6.140 |
CE |
O |
||
| 5h24 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -128.0 | 139.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.987 |
O |
O |
||
| MET | B:302 | B:376 | 1.0 | 0.005 | E | -132.9 | 136.6 | NA | NA | NA | |||||||||||||
| 5h25 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:302 | A:376 | 2.0 | 0.011 | E | -123.9 | 146.6 | 2.0 | 0.011 | 0.0 | ||||||
| MET | B:302 | B:376 | 0.0 | 0.0 | E | -130.4 | 146.1 | NA | NA | NA | |||||||||||||
| 5ttw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -137.7 | 150.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.548 |
CE |
O |
||
| MET | C:302 | C:376 | 0.0 | 0.0 | E | -133.7 | 147.7 | NA | NA | NA | |||||||||||||
| 5u5h | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -129.4 | 146.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.957 |
CE |
O |
||
| 5u5k | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | MET | A:302 | A:376 | 4.0 | 0.022 | E | -131.5 | 145.8 | 4.0 | 0.022 | 0.0 |
HOH |
5.828 |
CE |
O |
||
| 5u5t | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -128.8 | 145.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.038 |
CE |
O |
||
| MET | B:302 | B:376 | 0.0 | 0.0 | E | -127.5 | 143.1 | NA | NA | NA | |||||||||||||
| 5u62 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -129.3 | 145.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.710 |
CE |
O |
||
| MET | B:302 | B:376 | 0.0 | 0.0 | E | -130.0 | 142.1 | NA | NA | NA | |||||||||||||
| 6lo2 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-07-07 | MET | A:302 | A:376 | 0.0 | 0.0 | E | -130.9 | 145.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.405 |
CE |
O |
||
| MET | B:302 | B:376 | 0.0 | 0.0 | E | -130.7 | 141.7 | NA | NA | NA | |||||||||||||
| 6v3x | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | MET | A:302 | A:376 | 12.0 | 0.065 | E | -137.4 | 149.3 | 12.0 | 0.065 | 0.0 |
HOH |
3.709 |
CG |
O |
||
| 4x3e | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2015-01-21 | MET | A:302 | A:376 | 15.0 | 0.081 | E | -139.3 | 163.0 | 15.0 | 0.081 | 0.0 |
HOH |
5.973 |
CE |
O |
||
| 5hyn | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-11 | MET | B:302 | B:376 | 2.0 | 0.011 | E | -134.4 | 143.6 | 2.0 | 0.011 | 0.0 | ||||||
| MET | G:302 | G:376 | 1.0 | 0.005 | E | -130.1 | 141.6 | NA | NA | NA | |||||||||||||
| MET | L:302 | L:376 | 1.0 | 0.005 | E | -125.2 | 140.6 | NA | NA | NA | |||||||||||||
| MET | Q:302 | R:376 | 0.0 | 0.0 | E | -131.5 | 145.3 | NA | NA | NA | |||||||||||||
| 5ls6 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-02-22 | MET | B:302 | B:376 | 2.0 | 0.011 | E | -131.6 | 146.2 | 2.0 | 0.011 | 0.0 | ||||||
| MET | E:302 | E:376 | 1.0 | 0.005 | E | -128.5 | 145.3 | NA | NA | NA | |||||||||||||
| MET | H:302 | H:376 | 1.0 | 0.005 | E | -126.0 | 135.4 | NA | NA | NA | |||||||||||||
| MET | K:302 | K:376 | 2.0 | 0.011 | E | -129.6 | 145.6 | NA | NA | NA | |||||||||||||
| 5u69 | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | MET | A:304 | A:376 | 7.0 | 0.038 | E | -139.8 | 153.8 | 7.0 | 0.038 | 0.0 |
HOH |
3.338 |
CG |
O |
||
| 5u6d | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | MET | A:304 | A:376 | 10.0 | 0.054 | E | -135.9 | 153.4 | 10.0 | 0.054 | 0.0 |
HOH |
5.983 |
CE |
O |
||
| 5u8a | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | MET | A:304 | A:376 | 14.0 | 0.076 | E | -139.0 | 154.1 | 14.0 | 0.076 | 0.0 |
HOH |
5.714 |
N |
O |
||
| 5u8f | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-03-15 | MET | A:304 | A:376 | 12.0 | 0.065 | E | -137.9 | 152.5 | 12.0 | 0.065 | 0.0 |
HOH |
3.498 |
CG |
O |
||
| 3iiw | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2009-09-15 | MET | A:300 | A:376 | 22.0 | 0.119 | E | -141.3 | 161.6 | 22.0 | 0.119 | 0.0 |
HOH |
3.314 |
SD |
O |
||
| 5k0m | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-01-25 | MET | A:307 | A:376 | 16.0 | 0.086 | E | -134.0 | 148.6 | 16.0 | 0.086 | 0.0 |
HOH |
3.275 |
SD |
O |
||
| 5wuk | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2017-05-03 | MET | A:301 | A:376 | 1.0 | 0.005 | E | -128.2 | 143.1 | 1.0 | 0.005 | 0.0 |
HOH |
5.612 |
CG |
O |
||
| 6u4y | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2020-07-08 | MET | D:301 | D:376 | 1.0 | 0.005 | E | -129.3 | 148.4 | 1.0 | 0.005 | 0.0 | ||||||
| MET | E:301 | E:376 | 1.0 | 0.005 | E | -136.4 | 146.9 | 1.0 | 0.005 | 0.0 | |||||||||||||
| MET | F:301 | F:376 | 2.0 | 0.011 | E | -125.5 | 154.7 | 2.0 | 0.011 | 0.0 | |||||||||||||
| 6w7f | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | MET | A:303 | A:376 | 25.0 | 0.135 | E | -135.9 | 152.3 | 25.0 | 0.135 | 0.0 |
HOH |
6.661 |
SD |
O |
||
| 6w7g | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2020-07-08 | MET | A:303 | A:376 | 13.0 | 0.07 | E | -136.9 | 153.5 | 13.0 | 0.07 | 0.0 |
HOH |
3.784 |
CG |
O |
||
| 7msb | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | MET | A:303 | A:376 | 8.0 | 0.043 | E | -136.7 | 155.0 | 8.0 | 0.043 | 0.0 |
HOH |
3.754 |
SD |
O |
||
| 7msd | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2021-10-20 | MET | A:303 | A:376 | 16.0 | 0.086 | E | -134.2 | 153.5 | 16.0 | 0.086 | 0.0 |
HOH |
5.944 |
CE |
O |
||
| 3iiy | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | MET | A:300 | A:376 | 1.0 | 0.005 | E | -138.5 | 168.5 | 1.0 | 0.005 | 0.0 |
HOH |
7.009 |
O |
O |
||
| 3ij0 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | MET | A:300 | A:376 | 25.0 | 0.135 | E | -138.0 | 168.7 | 25.0 | 0.135 | 0.0 |
HOH |
6.855 |
O |
O |
||
| 3ij1 | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | MET | A:300 | A:376 | 22.0 | 0.119 | E | -143.0 | 163.0 | 22.0 | 0.119 | 0.0 |
HOH |
3.638 |
CE |
O |
||
| 3ijc | 1 | O75530 | 99.73 | 0.0 |
X-RAY |
2009-09-15 | MET | A:300 | A:376 | 1.0 | 0.005 | E | -138.6 | 152.5 | 1.0 | 0.005 | 0.0 |
HOH |
3.761 |
CE |
O |
||
| 2qxv | 1 | Q921E6 | 100.0 | 0.0 |
X-RAY |
2007-08-28 | MET | A:296 | A:368 | 6.0 | 0.032 | E | -133.8 | 140.3 | 6.0 | 0.032 | 0.0 |
HOH |
4.870 |
SD |
O |
||
| 4w2r | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | MET | C:297 | E:362 | 11.0 | 0.059 | E | -146.5 | 158.4 | NA | NA | NA | ||||||
| MET | D:297 | F:362 | 8.0 | 0.043 | E | -139.2 | 152.3 | 8.0 | 0.043 | 0.0 | |||||||||||||
| 5ij7 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | MET | C:297 | E:362 | 11.0 | 0.059 | E | -121.4 | 151.4 | 11.0 | 0.059 | 0.0 | ||||||
| MET | D:297 | F:362 | 16.0 | 0.086 | E | -119.2 | 144.7 | NA | NA | NA | |||||||||||||
| 5ij8 | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2016-05-04 | MET | C:297 | E:362 | 15.0 | 0.081 | E | -121.5 | 153.6 | NA | NA | NA | ||||||
| MET | D:297 | F:362 | 14.0 | 0.076 | E | -121.2 | 153.3 | 14.0 | 0.076 | 0.0 | |||||||||||||
| 6b3w | 2 | O75530 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | MET | C:297 | E:362 | 15.0 | 0.081 | E | -117.8 | 142.6 | NA | NA | NA | ||||||
| MET | D:297 | F:362 | 7.0 | 0.038 | E | -119.4 | 133.6 | 7.0 | 0.038 | 0.0 | |||||||||||||
| 6v3y | 1 | O75530 | 100.0 | 0.0 |
X-RAY |
2021-05-26 | MET | A:296 | A:376 | 14.0 | 0.076 | E | -142.4 | 160.9 | 14.0 | 0.076 | 0.0 |
HOH |
4.113 |
CE |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o75530-f1 | 1 | O75530 | 100.0 | 0.0 | MET | A:376 | A:376 | 0.0 | 0.0 | E | -124.6 | 136.6 | |