Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85989482 . G A CCDS8273.1:NM_003797.3:c.1241cGa>cAa_NP_003788.2:p.414R>Q Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 ARG D:414 L:414 31.0 0.138 E -89.3 -61.0 1.0 0.004 0.134 L:Q92833:0.133
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 ARG E:414 L:414 38.0 0.169 E -83.0 -63.2 0.0 0.0 0.169 B:Q92833:0.169
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 ARG C:414 L:414 34.0 0.151 E -86.4 -44.3 4.0 0.018 0.133 F:Q92833:0.133
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 ARG B:414 B:414 27.0 0.12 E -106.5 -38.1 27.0 0.12 0.0
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 ARG D:414 B:414 25.0 0.111 -104.0 -41.0 25.0 0.111 0.0
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 ARG B:414 B:414 28.0 0.124 -106.0 -40.2 28.0 0.124 0.0
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 ARG B:415 B:414 26.0 0.116 E -76.1 -50.5 26.0 0.116 0.0
ARG D:415 D:414 72.0 0.32 -86.1 360.0 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 ARG A:375 A:414 27.0 0.12 E -92.0 -32.6 1.0 0.004 0.116 B:None:0.116
 HOH
 2.826
 O
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:375 A:414 29.0 0.129 E -85.3 -29.5 3.0 0.013 0.116 B:None:0.116
 HOH
 2.820
 O
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:375 A:414 29.0 0.129 E -85.4 -28.0 3.0 0.013 0.116 B:None:0.116
 HOH
 2.718
 O
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 ARG A:375 A:414 29.0 0.129 E -84.6 -42.4 29.0 0.129 0.0 UNX
UNX
UNX
HOH
 7.082
8.938
7.188
2.834
 NH1
NH1
NH2
O
 UNK
UNK
UNK
O
ARG B:375 B:414 28.0 0.124 E -82.2 -41.7 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 ARG A:341 A:414 26.0 0.116 E -76.3 -38.3 26.0 0.116 0.0 UNX
 6.406
 NH1
 UNK
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 ARG A:349 A:414 30.0 0.133 E -84.3 -32.9 30.0 0.133 0.0 LQA
HOH
 3.199
3.693
 CD
C
 O21
O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:339 A:414 29.0 0.129 E -90.0 -27.8 29.0 0.129 0.0 HOH
 3.747
 C
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:339 A:414 30.0 0.133 E -89.7 -30.5 1.0 0.004 0.129 B:None:0.129
 HOH
 3.567
 O
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ARG A:339 A:414 30.0 0.133 E -95.4 -26.9 4.0 0.018 0.115 B:None:0.116
 HOH
 2.735
 O
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ARG A:339 A:414 34.0 0.151 E -75.2 -37.3 34.0 0.151 0.0 L9K
HOH
 3.530
3.540
 NH2
C
 C2
O
ARG B:339 B:414 33.0 0.147 E -75.7 -37.1 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ARG A:339 A:414 33.0 0.147 E -72.8 -39.2 33.0 0.147 0.0 L9W
HOH
 3.406
3.485
 O
C
 C20
O
ARG B:339 B:414 33.0 0.147 E -72.3 -39.5 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ARG A:339 A:414 34.0 0.151 E -67.4 -47.6 34.0 0.151 0.0 L9W
HOH
 3.486
3.205
 NH2
O
 C2
O
ARG B:339 B:414 34.0 0.151 E -67.9 -48.1 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ARG A:339 A:414 35.0 0.156 E -72.2 -40.2 35.0 0.156 0.0 L9W
HOH
 3.545
3.417
 O
O
 C20
O
ARG B:339 B:414 34.0 0.151 E -72.7 -40.5 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:339 A:414 32.0 0.142 E -75.5 -37.7 32.0 0.142 0.0 L9W
HOH
 3.388
3.479
 O
C
 C20
O
ARG B:339 B:414 33.0 0.147 E -74.4 -37.6 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:339 A:414 33.0 0.147 E -73.0 -32.9 33.0 0.147 0.0 L9W
HOH
 3.423
3.400
 O
C
 C20
O
ARG B:339 B:414 31.0 0.138 E -72.9 -33.2 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ARG A:339 A:414 34.0 0.151 E -73.4 -38.7 34.0 0.151 0.0 L9W
HOH
 3.441
3.530
 O
O
 C20
O
ARG B:339 B:414 32.0 0.142 E -72.8 -39.5 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 ARG A:340 A:414 31.0 0.138 E -65.8 -44.6 31.0 0.138 0.0 73K
HOH
 3.603
2.715
 NH1
O
 C21
O
ARG B:340 B:414 27.0 0.12 E -65.1 -51.2 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:340 A:414 30.0 0.133 E -73.1 -38.1 30.0 0.133 0.0 LQB
HOH
 3.731
3.488
 NH2
C
 C21
O
ARG B:340 B:414 28.0 0.124 E -73.8 -40.6 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:340 A:414 28.0 0.124 E -69.5 -41.0 28.0 0.124 0.0 LQD
HOH
 3.483
3.372
 NH2
NH2
 C24
O
ARG B:340 B:414 29.0 0.129 E -69.6 -35.5 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:340 A:414 29.0 0.129 E -71.8 -37.6 29.0 0.129 0.0 LQE
HOH
 3.341
3.603
 NH1
C
 C13
O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:340 A:414 35.0 0.156 E -79.1 -38.3 35.0 0.156 0.0 LQF
HOH
 3.557
2.722
 NH2
O
 C20
O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:340 A:414 28.0 0.124 E -69.3 -43.5 28.0 0.124 0.0 LQG
HOH
 4.111
3.515
 CD
O
 N
O
ARG B:340 B:414 26.0 0.116 E -65.7 -49.0 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:340 A:414 24.0 0.107 E -65.9 -42.4 24.0 0.107 0.0 LQH
HOH
 3.331
3.410
 NH2
O
 C11
O
ARG B:340 B:414 17.0 0.076 E -71.7 -56.0 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:340 A:414 30.0 0.133 E -83.9 -34.2 1.0 0.004 0.129 B:None:0.129
 UNX
UNX
HOH
 5.939
8.077
2.774
 O
O
O
 UNK
UNK
O
ARG C:340 C:414 30.0 0.133 E -84.4 -36.6 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:340 A:414 27.0 0.12 E -70.6 -44.1 27.0 0.12 0.0 7VV
HOH
 2.373
3.036
 O
NH1
 H47
O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:340 A:414 30.0 0.133 E -73.7 -42.0 30.0 0.133 0.0 7VY
HOH
 3.448
3.522
 O
O
 C15
O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:340 A:414 28.0 0.124 E -77.0 -38.5 28.0 0.124 0.0 7W7
HOH
 3.617
3.241
 O
NH1
 C8
O
ARG B:340 B:414 28.0 0.124 E -77.3 -37.3 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ARG A:340 A:414 26.0 0.116 E -78.4 -36.5 26.0 0.116 0.0 7WD
HOH
 3.631
3.077
 O
NH1
 C8
O
ARG B:340 B:414 28.0 0.124 E -76.2 -37.0 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 ARG A:340 A:414 33.0 0.147 E -69.6 -38.3 33.0 0.147 0.0 EJU
HOH
 3.739
3.421
 O
O
 C29
O
ARG B:340 B:414 31.0 0.138 E -73.6 -39.6 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ARG A:340 A:414 30.0 0.133 E -85.4 -33.2 1.0 0.004 0.129 B:None:0.129
 HOH
 2.766
 O
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 ARG A:340 A:414 29.0 0.129 E -79.4 -30.0 0.0 0.0 0.129 B:None:0.129
 HOH
 2.707
 O
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 ARG B:340 B:414 31.0 0.138 E -67.6 -49.9 0.0 0.0 0.138 E:None:0.138
ARG G:340 G:414 32.0 0.142 E -70.2 -53.8 NA NA NA
ARG L:340 L:414 31.0 0.138 E -70.5 -47.0 NA NA NA
ARG Q:340 R:414 27.0 0.12 E -70.2 -48.2 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 ARG B:340 B:414 30.0 0.133 E -52.5 -47.1 0.0 0.0 0.133 M:None:0.133
ARG E:340 E:414 27.0 0.12 -52.1 -82.5 NA NA NA
ARG H:340 H:414 30.0 0.133 E -67.3 -29.2 NA NA NA
ARG K:340 K:414 30.0 0.133 E -73.3 -39.9 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:342 A:414 33.0 0.147 E -81.6 -32.9 33.0 0.147 0.0 LQD
HOH
 3.623
3.269
 NH1
NH1
 C24
O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:342 A:414 33.0 0.147 E -79.8 -35.6 33.0 0.147 0.0 7XG
HOH
 3.534
3.146
 NH2
NH2
 C9
O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:342 A:414 33.0 0.147 E -80.4 -35.9 33.0 0.147 0.0 82D
HOH
 3.638
3.393
 NH1
NH1
 C6
O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ARG A:342 A:414 33.0 0.147 E -78.8 -34.8 33.0 0.147 0.0 82G
HOH
 3.661
2.944
 NH1
O
 C1
O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 ARG A:338 A:414 29.0 0.129 E -86.6 -35.1 3.0 0.013 0.116 B:None:0.116
 HOH
 2.815
 O
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ARG A:345 A:414 34.0 0.151 E -80.4 -33.3 34.0 0.151 0.0 6PU
HOH
 3.257
3.171
 NH2
NH1
 C14
O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 ARG A:339 A:414 31.0 0.138 E -73.7 -42.1 31.0 0.138 0.0 GOL
73K
HOH
 8.735
3.441
2.656
 NH2
NH1
O
 O2
C21
O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 ARG D:339 D:414 29.0 0.129 E -79.8 -37.9 29.0 0.129 0.0
ARG E:339 E:414 29.0 0.129 E -86.0 -36.5 29.0 0.129 0.0
ARG F:339 F:414 30.0 0.133 E -85.8 -31.4 30.0 0.133 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ARG A:341 A:414 35.0 0.156 E -80.8 -34.4 35.0 0.156 0.0 Q3D
HOH
 2.860
3.066
 O
NH2
 H5
O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ARG A:341 A:414 32.0 0.142 E -81.0 -35.4 32.0 0.142 0.0 Q3A
HOH
 2.984
2.946
 O
NH2
 H12
O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ARG A:341 A:414 33.0 0.147 E -76.8 -37.2 33.0 0.147 0.0 ZNG
HOH
 3.564
3.140
 O
NH2
 C16
O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ARG A:341 A:414 29.0 0.129 E -79.4 -36.1 29.0 0.129 0.0 ZMY
HOH
 3.212
3.386
 NH2
NH2
 N1
O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:338 A:414 27.0 0.12 E -86.5 -32.9 4.0 0.018 0.102 B:None:0.102
 HOH
 2.763
 O
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:338 A:414 28.0 0.124 E -89.2 -28.4 4.0 0.018 0.106 B:None:0.107
 HOH
 2.776
 O
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:338 A:414 28.0 0.124 E -88.7 -34.5 1.0 0.004 0.12 B:None:0.12
 HOH
 2.771
 O
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ARG A:338 A:414 24.0 0.107 E -91.2 -37.2 24.0 0.107 0.0 NDS
HOH
 3.328
3.019
 NH2
O
 O3
O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 ARG A:334 A:406 31.0 0.138 E -71.5 -37.9 31.0 0.138 0.0 HOH
 2.846
 O
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ARG C:335 E:400 30.0 0.133 E -79.7 -43.8 NA NA NA
ARG D:335 F:400 31.0 0.138 E -78.9 -35.0 31.0 0.138 0.0
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ARG C:335 E:400 28.0 0.124 E -74.0 -39.5 28.0 0.124 0.0 HOH
 8.142
 CG
 O
ARG D:335 F:400 28.0 0.124 E -73.3 -40.5 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ARG C:335 E:400 29.0 0.129 E -74.2 -38.8 NA NA NA
ARG D:335 F:400 28.0 0.124 E -73.8 -38.5 28.0 0.124 0.0
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ARG C:335 E:400 25.0 0.111 E -87.6 -40.3 NA NA NA
ARG D:335 F:400 25.0 0.111 E -89.5 -29.1 25.0 0.111 0.0
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ARG A:334 A:414 29.0 0.129 E -85.0 -33.1 0.0 0.0 0.129 B:None:0.129
 HOH
 2.952
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 ARG A:414 A:414 31.0 0.138 E -72.5 -40.9