Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 111160290 . C A CCDS58279.1:NM_001244974.1:c.734tGt>tTt_NP_001231903.1:p.245C>F Homo sapiens protein phosphatase 1 catalytic subunit gamma (PPP1CC), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1it6 1 P36873 100.0 0.0 X-RAY
2002-05-22 CYS A:245 A:245 0.0 0.0 E -121.0 129.4 0.0 0.0 0.0 HOH
7.594
O
O
CYS B:245 B:245 0.0 0.0 E -119.6 121.5 NA NA NA
1jk7 1 P36873 100.0 0.0 X-RAY
2001-08-15 CYS A:245 A:245 0.0 0.0 E -119.7 118.4 0.0 0.0 0.0 BME
HOH
8.300
8.060
CB
O
C2
O
2bcd 1 P36873 100.0 0.0 X-RAY
2006-01-17 CYS A:245 A:245 0.0 0.0 E -106.7 122.6 0.0 0.0 0.0 HOH
8.025
O
O
2bdx 1 P36873 100.0 0.0 X-RAY
2006-01-17 CYS A:245 A:245 0.0 0.0 E -102.3 117.8 0.0 0.0 0.0 HOH
7.728
O
O
4ut2 1 P36873 100.0 0.0 X-RAY
2015-07-22 CYS A:245 A:245 0.0 0.0 E -115.1 117.0 0.0 0.0 0.0 HOH
7.767
O
O
CYS B:245 B:245 0.0 0.0 E -115.1 116.9 NA NA NA
4ut3 1 P36873 100.0 0.0 X-RAY
2015-07-22 CYS A:245 A:245 0.0 0.0 E -122.2 119.9 0.0 0.0 0.0 HOH
7.786
O
O
4ut3 2 P36873 100.0 0.0 X-RAY
2015-07-22 CYS B:245 B:245 0.0 0.0 E -124.1 117.8 NA NA NA
4v0u 2 P63087 99.69 0.0 X-RAY
2015-03-25 CYS D:245 D:245 0.0 0.0 E -116.6 118.8 NA NA NA
CYS F:245 F:245 0.0 0.0 E -116.5 118.8 NA NA NA
CYS H:245 H:245 0.0 0.0 E -116.7 118.8 NA NA NA
CYS J:245 J:245 0.0 0.0 E -116.5 118.8 0.0 0.0 0.0
CYS N:245 N:245 0.0 0.0 E -116.4 118.7 NA NA NA
2o8a 1 P63088 99.69 0.0 X-RAY
2007-07-17 CYS A:251 A:245 0.0 0.0 E -118.1 123.6 0.0 0.0 0.0 HOH
7.945
O
O
CYS C:251 B:245 0.0 0.0 E -118.9 120.4 NA NA NA
2o8g 1 P63088 99.69 0.0 X-RAY
2007-07-17 CYS A:251 A:245 0.0 0.0 E -118.4 121.4 0.0 0.0 0.0 HOH
7.907
O
O
CYS C:251 B:245 0.0 0.0 E -119.1 124.6 NA NA NA
5inb 1 P36873 100.0 0.0 X-RAY
2016-10-05 CYS A:242 A:245 0.0 0.0 E -120.9 122.4 0.0 0.0 0.0 HOH
7.825
O
O
5j28 1 P36873 100.0 0.0 X-RAY
2016-10-05 CYS A:242 A:245 0.0 0.0 E -123.8 117.9 0.0 0.0 0.0 HOH
7.592
O
O
CYS B:242 B:245 0.0 0.0 E -125.7 124.3 NA NA NA
1fjm 1 P08129 90.66 0.0 X-RAY
1996-06-20 CYS A:245 A:245 0.0 0.0 E -115.3 120.3 0.0 0.0 0.0 BME
HOH
8.332
7.786
CB
O
C2
O
CYS B:245 B:245 0.0 0.0 E -115.7 119.8 NA NA NA
4g9j 1 P62136 90.66 0.0 X-RAY
2012-09-19 CYS A:246 A:245 0.0 0.0 E -102.8 127.1 0.0 0.0 0.0
CYS B:246 B:245 0.0 0.0 E -108.3 116.8 NA NA NA
6g0i 1 P62136 90.66 0.0 X-RAY
2018-11-21 CYS A:246 A:245 0.0 0.0 E -107.2 118.8 0.0 0.0 0.0 HOH
7.823
O
O
6g0j 1 P62136 90.66 0.0 X-RAY
2018-11-21 CYS A:246 A:245 0.0 0.0 E -115.1 117.2 0.0 0.0 0.0 HOH
7.620
O
O
6dcx 1 P62136 90.66 0.0 X-RAY
2019-05-15 CYS A:254 A:245 0.0 0.0 E -119.2 119.9 0.0 0.0 0.0
CYS B:254 B:245 0.0 0.0 E -119.6 119.1 NA NA NA
6zk6 1 P62136 90.36 0.0 X-RAY
2020-11-18 CYS A:246 A:245 0.0 0.0 E -118.9 116.9 0.0 0.0 0.0 HOH
7.709
O
O
5zqv 1 P62137 91.95 0.0 X-RAY
2019-03-13 CYS A:245 A:245 0.0 0.0 E -113.0 126.5 0.0 0.0 0.0
CYS B:245 B:245 0.0 0.0 E -108.4 129.9 NA NA NA
CYS C:245 C:245 0.0 0.0 E -101.5 136.3 0.0 0.0 0.0
CYS D:245 D:245 0.0 0.0 E -109.5 132.6 NA NA NA
4v0v 1 P63087 100.0 0.0 X-RAY
2015-03-25 CYS A:240 A:245 0.0 0.0 E -115.4 119.5 0.0 0.0 0.0 HOH
7.783
O
O
CYS C:240 C:245 0.0 0.0 E -116.2 120.6 NA NA NA
4v0w 1 P63087 100.0 0.0 X-RAY
2015-03-25 CYS A:240 A:245 0.0 0.0 E -119.9 119.3 0.0 0.0 0.0 HOH
7.813
O
O
CYS C:240 C:245 0.0 0.0 E -119.1 117.3 NA NA NA
4v0x 1 P63087 100.0 0.0 X-RAY
2015-03-25 CYS A:240 A:245 0.0 0.0 E -115.1 123.4 0.0 0.0 0.0 HOH
7.780
O
O
3egg 1 P62136 90.58 0.0 X-RAY
2010-03-23 CYS A:244 A:245 0.0 0.0 E -116.2 119.2 0.0 0.0 0.0
CYS B:244 B:245 0.0 0.0 E -117.6 123.3 NA NA NA
3egh 1 P62136 90.58 0.0 X-RAY
2010-03-23 CYS A:244 A:245 0.0 0.0 E -112.4 114.8 0.0 0.0 0.0 HOH
7.769
O
O
CYS B:244 B:245 0.0 0.0 E -113.2 119.8 NA NA NA
3hvq 1 P62136 90.58 0.0 X-RAY
2010-03-23 CYS A:244 A:245 0.0 0.0 E -106.8 119.5 0.0 0.0 0.0 HOH
7.826
O
O
CYS B:244 B:245 0.0 0.0 E -109.9 117.7 0.0 0.0 0.0 HOH
7.803
O
O
6ghm 1 P62136 90.58 0.0 X-RAY
2019-02-27 CYS A:244 A:245 0.0 0.0 E -122.6 115.6 0.0 0.0 0.0 HOH
7.812
O
O
CYS B:244 B:245 0.0 0.0 E -116.2 117.6 NA NA NA
3n5u 1 P62136 96.67 0.0 X-RAY
2010-08-11 CYS A:245 A:245 0.0 0.0 E -112.7 121.9 0.0 0.0 0.0
CYS B:245 B:245 0.0 0.0 E -112.5 121.3 0.0 0.0 0.0
6obn 1 P62136 96.67 0.0 X-RAY
2019-09-18 CYS A:250 A:245 0.0 0.0 E -114.8 118.3 0.0 0.0 0.0 MPD
HOH
8.590
8.678
CB
C
C3
O
CYS B:250 B:245 0.0 0.0 E -114.4 118.5 NA NA NA
6obp 1 P62136 96.67 0.0 X-RAY
2019-09-18 CYS A:250 A:245 0.0 0.0 E -115.7 109.6 0.0 0.0 0.0
6zej 1 P62136,Q4VY12 94.46 0.0 X-RAY
2020-09-30 CYS A:244 D:244 0.0 0.0 E -120.6 122.4 0.0 0.0 0.0 HOH
7.612
HA
O
CYS B:244 A:244 0.0 0.0 E -114.5 120.7 NA NA NA
CYS C:244 F:244 0.0 0.0 E -114.3 125.6 NA NA NA
CYS D:244 I:244 0.0 0.0 E -124.5 124.1 NA NA NA
CYS E:244 L:244 0.0 0.0 E -121.1 120.2 NA NA NA
CYS F:244 O:244 0.0 0.0 E -123.3 115.4 NA NA NA
6zeh 1 P62136,Q13813 96.33 0.0 X-RAY
2020-09-30 CYS A:244 A:245 0.0 0.0 E -118.8 120.9 0.0 0.0 0.0 HOH
7.678
HA
O
CYS C:244 B:245 0.0 0.0 E -117.1 117.5 NA NA NA
3v4y 1 P62136 96.33 0.0 X-RAY
2012-10-31 CYS A:244 A:245 0.0 0.0 E -123.3 115.4 0.0 0.0 0.0 HOH
7.716
HA
O
CYS C:244 C:245 0.0 0.0 E -117.1 117.1 NA NA NA
CYS E:244 E:245 0.0 0.0 E -116.8 115.7 NA NA NA
CYS G:244 G:245 0.0 0.0 E -111.0 120.1 NA NA NA
6zei 1 P62136,Q9UQB8 96.32 0.0 X-RAY
2020-09-30 CYS A:244 A:245 0.0 0.0 E -116.7 116.4 0.0 0.0 0.0 GOL
HOH
9.410
7.679
HA
O
H31
O
CYS C:244 B:245 0.0 0.0 E -119.8 117.0 NA NA NA
6zeg 1 P62136,Q9UQB8 96.32 0.0 X-RAY
2020-09-30 CYS A:244 A:245 0.0 0.0 E -117.8 118.8 0.0 0.0 0.0 HOH
7.656
HA
O
CYS C:244 B:245 0.0 0.0 E -118.7 117.3 NA NA NA
3e7a 1 P62136 96.63 0.0 X-RAY
2008-11-04 CYS A:244 A:245 0.0 0.0 E -117.1 120.3 0.0 0.0 0.0 HOH
7.742
O
O
CYS B:244 B:245 0.0 0.0 E -120.3 122.1 NA NA NA
3e7b 1 P62136 96.63 0.0 X-RAY
2008-11-04 CYS A:244 A:245 0.0 0.0 E -120.2 121.6 0.0 0.0 0.0 HOH
7.861
O
O
CYS B:244 B:245 0.0 0.0 E -119.6 121.2 NA NA NA
4mov 1 P62136 96.63 0.0 X-RAY
2014-03-26 CYS A:244 A:245 0.0 0.0 E -117.9 118.7 0.0 0.0 0.0 HOH
7.707
O
O
CYS B:244 B:245 0.0 0.0 E -118.5 120.5 NA NA NA
4moy 1 P62136 96.63 0.0 X-RAY
2014-03-26 CYS A:244 A:245 0.0 0.0 E -112.3 119.2 0.0 0.0 0.0 HOH
7.796
O
O
4mp0 1 P62136 96.63 0.0 X-RAY
2014-03-26 CYS A:244 A:245 0.0 0.0 E -116.4 116.9 0.0 0.0 0.0 HOH
7.689
O
O
CYS B:244 C:245 0.0 0.0 E -115.8 117.4 NA NA NA
4xpn 1 P62136 96.63 0.0 X-RAY
2015-07-01 CYS A:244 A:245 0.0 0.0 E -112.9 116.8 0.0 0.0 0.0 HOH
7.794
O
O
CYS C:244 C:245 0.0 0.0 E -113.1 117.7 NA NA NA
5ioh 1 P62136 96.63 0.0 X-RAY
2016-10-05 CYS A:244 A:245 0.0 0.0 E -116.9 118.3 0.0 0.0 0.0 HOH
7.585
O
O
CYS C:244 C:245 0.0 0.0 E -116.5 118.7 NA NA NA
6alz 1 P62136 96.63 0.0 X-RAY
2017-11-29 CYS A:244 A:245 0.0 0.0 E -113.8 119.4 0.0 0.0 0.0 HOH
7.860
O
O
CYS B:244 B:245 0.0 0.0 E -113.6 121.6 NA NA NA
6czo 1 P62136 96.63 0.0 X-RAY
2019-01-23 CYS A:244 A:245 0.0 0.0 E -110.6 108.7 0.0 0.0 0.0 HOH
7.861
O
O
CYS C:244 C:245 0.0 0.0 E -108.2 116.4 NA NA NA
6dno 1 P62136 96.63 0.0 X-RAY
2019-01-23 CYS A:244 A:245 0.0 0.0 E -120.4 120.5 0.0 0.0 0.0 HOH
7.820
O
O
6zee 1 P62136 96.63 0.0 X-RAY
2020-09-30 CYS A:244 P:245 0.0 0.0 E -110.4 118.8 0.0 0.0 0.0 HOH
7.886
HA
O
CYS B:244 Q:245 0.0 0.0 E -111.0 125.4 0.0 0.0 0.0 EDO
HOH
9.586
7.586
HA
HA
H21
O
CYS C:244 B:245 0.0 0.0 E -115.9 119.3 0.0 0.0 0.0 EDO
HOH
9.710
7.736
HA
O
H21
O
CYS D:244 A:245 0.0 0.0 E -117.5 117.2 0.0 0.0 0.0 HOH
7.773
O
O
CYS E:244 I:245 0.0 0.0 E -115.5 118.3 0.0 0.0 0.0 HOH
7.580
O
O
CYS F:244 K:245 0.0 0.0 E -119.1 114.0 0.0 0.0 0.0 HOH
7.773
HA
O
6zef 1 P62136 96.63 0.0 X-RAY
2020-09-30 CYS A:244 A:245 0.0 0.0 E -116.1 120.5 0.0 0.0 0.0 HOH
7.783
HA
O
CYS B:244 B:245 0.0 0.0 E -118.1 121.1 NA NA NA
1u32 1 P36873 98.29 0.0 X-RAY
2004-08-17 CYS A:240 A:245 0.0 0.0 E -118.1 116.6 0.0 0.0 0.0 BME
HOH
8.015
7.830
CB
O
C2
O
5zt0 1 P62137 97.28 0.0 X-RAY
2019-03-13 CYS A:239 A:245 0.0 0.0 E -114.5 129.1 0.0 0.0 0.0
CYS B:239 B:245 0.0 0.0 E -119.8 137.1 NA NA NA
CYS C:239 C:245 0.0 0.0 E -116.7 131.3 NA NA NA
CYS D:239 D:245 0.0 0.0 E -118.7 131.2 NA NA NA
CYS E:239 E:245 0.0 0.0 E -117.9 129.9 NA NA NA
CYS F:239 F:245 0.0 0.0 E -116.4 129.1 NA NA NA
6obr 1 P62136 96.3 0.0 X-RAY
2019-09-18 CYS A:244 A:245 0.0 0.0 E -116.6 119.8 0.0 0.0 0.0 HOH
7.752
O
O
CYS B:244 B:245 0.0 0.0 E -114.9 120.3 NA NA NA
6obq 1 P62136 96.3 0.0 X-RAY
2019-09-18 CYS A:244 A:245 0.0 0.0 E -119.5 117.9 0.0 0.0 0.0 HOH
7.862
O
O
CYS B:244 B:245 0.0 0.0 E -118.4 116.6 NA NA NA
6obs 1 P62136 96.3 0.0 X-RAY
2019-09-18 CYS A:244 A:245 0.0 0.0 E -119.4 118.2 0.0 0.0 0.0 HOH
7.766
O
O
CYS B:244 B:245 0.0 0.0 E -119.0 117.0 NA NA NA
6obu 1 P62136 96.3 0.0 X-RAY
2019-09-18 CYS A:244 A:245 0.0 0.0 E -119.2 119.3 0.0 0.0 0.0 HOH
7.835
O
O
CYS B:244 B:245 0.0 0.0 E -120.8 119.2 NA NA NA
7nzm 2 P62139 97.28 0.0 EM
2021-09-29 CYS B:239 B:245 16.0 0.119 E -125.7 119.2 16.0 0.119 0.0
1s70 1 P62140 89.06 0.0 X-RAY
2004-06-22 CYS A:247 A:245 0.0 0.0 E -93.7 135.6 0.0 0.0 0.0 HOH
7.964
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p36873-f1 1 P36873 100.0 0.0 CYS A:245 A:245 0.0 0.0 E -111.3 118.9
af-p62136-f1 1 P62136 90.66 0.0 CYS A:245 A:245 0.0 0.0 E -111.9 119.9
af-p62140-f1 1 P62140 89.06 0.0 CYS A:244 A:244 0.0 0.0 E -111.9 121.0