Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 111162504 . C A CCDS58279.1:NM_001244974.1:c.484Gca>Tca_NP_001231903.1:p.162A>S Homo sapiens protein phosphatase 1 catalytic subunit gamma (PPP1CC), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1it6 1 P36873 100.0 0.0 X-RAY
2002-05-22 ALA A:162 A:162 0.0 0.0 E -151.7 172.6 0.0 0.0 0.0 HOH
4.731
N
O
ALA B:162 B:162 0.0 0.0 E -148.4 168.0 NA NA NA
1jk7 1 P36873 100.0 0.0 X-RAY
2001-08-15 ALA A:162 A:162 0.0 0.0 E -155.9 167.9 0.0 0.0 0.0 HOH
4.887
N
O
2bcd 1 P36873 100.0 0.0 X-RAY
2006-01-17 ALA A:162 A:162 0.0 0.0 E -145.2 161.2 0.0 0.0 0.0 HOH
4.776
N
O
2bdx 1 P36873 100.0 0.0 X-RAY
2006-01-17 ALA A:162 A:162 0.0 0.0 E -150.0 159.7 0.0 0.0 0.0 HOH
4.670
N
O
4ut2 1 P36873 100.0 0.0 X-RAY
2015-07-22 ALA A:162 A:162 0.0 0.0 E -158.7 162.3 0.0 0.0 0.0 HOH
4.834
N
O
ALA B:162 B:162 0.0 0.0 E -158.4 162.4 NA NA NA
4ut3 1 P36873 100.0 0.0 X-RAY
2015-07-22 ALA A:162 A:162 0.0 0.0 E -156.1 163.0 0.0 0.0 0.0 HOH
4.586
N
O
4ut3 2 P36873 100.0 0.0 X-RAY
2015-07-22 ALA B:162 B:162 0.0 0.0 E -155.8 163.6 NA NA NA
4v0u 2 P63087 99.69 0.0 X-RAY
2015-03-25 ALA D:162 D:162 0.0 0.0 E -148.9 169.2 NA NA NA
ALA F:162 F:162 0.0 0.0 E -149.0 169.2 NA NA NA
ALA H:162 H:162 0.0 0.0 E -148.9 169.2 NA NA NA
ALA J:162 J:162 0.0 0.0 E -148.9 169.2 0.0 0.0 0.0
ALA N:162 N:162 0.0 0.0 E -149.0 169.1 NA NA NA
2o8a 1 P63088 99.69 0.0 X-RAY
2007-07-17 ALA A:168 A:162 0.0 0.0 E -154.6 166.1 0.0 0.0 0.0 HOH
4.762
N
O
ALA C:168 B:162 0.0 0.0 E -152.4 167.5 NA NA NA
2o8g 1 P63088 99.69 0.0 X-RAY
2007-07-17 ALA A:168 A:162 0.0 0.0 E -150.5 164.0 0.0 0.0 0.0 HOH
4.657
N
O
ALA C:168 B:162 0.0 0.0 E -156.0 163.7 NA NA NA
5inb 1 P36873 100.0 0.0 X-RAY
2016-10-05 ALA A:159 A:162 0.0 0.0 E -152.8 163.9 0.0 0.0 0.0 GOL
NA
HOH
7.586
9.474
4.667
O
O
N
O3
NA
O
5j28 1 P36873 100.0 0.0 X-RAY
2016-10-05 ALA A:159 A:162 0.0 0.0 E -151.2 164.4 0.0 0.0 0.0 NA
HOH
9.452
4.636
C
N
NA
O
ALA B:159 B:162 0.0 0.0 E -149.1 168.1 NA NA NA
1fjm 1 P08129 90.66 0.0 X-RAY
1996-06-20 ALA A:162 A:162 0.0 0.0 E -151.2 171.2 0.0 0.0 0.0 HOH
4.816
N
O
ALA B:162 B:162 0.0 0.0 E -155.6 171.4 NA NA NA
4g9j 1 P62136 90.66 0.0 X-RAY
2012-09-19 ALA A:163 A:162 0.0 0.0 E -141.8 166.7 0.0 0.0 0.0
ALA B:163 B:162 0.0 0.0 E -139.9 164.5 NA NA NA
6g0i 1 P62136 90.66 0.0 X-RAY
2018-11-21 ALA A:163 A:162 0.0 0.0 E -154.9 164.2 0.0 0.0 0.0 HOH
4.696
N
O
6g0j 1 P62136 90.66 0.0 X-RAY
2018-11-21 ALA A:163 A:162 0.0 0.0 E -162.8 165.7 0.0 0.0 0.0 HOH
4.657
N
O
6dcx 1 P62136 90.66 0.0 X-RAY
2019-05-15 ALA A:171 A:162 0.0 0.0 E -152.5 163.2 0.0 0.0 0.0
ALA B:171 B:162 0.0 0.0 E -150.9 162.4 NA NA NA
6zk6 1 P62136 90.36 0.0 X-RAY
2020-11-18 ALA A:163 A:162 0.0 0.0 E -154.9 164.2 0.0 0.0 0.0 HOH
4.749
N
O
5zqv 1 P62137 91.95 0.0 X-RAY
2019-03-13 ALA A:162 A:162 0.0 0.0 E -145.2 165.5 0.0 0.0 0.0
ALA B:162 B:162 0.0 0.0 E -152.1 164.9 NA NA NA
ALA C:162 C:162 0.0 0.0 E -138.5 160.5 0.0 0.0 0.0
ALA D:162 D:162 0.0 0.0 E -151.3 159.8 NA NA NA
4v0v 1 P63087 100.0 0.0 X-RAY
2015-03-25 ALA A:157 A:162 0.0 0.0 E -151.9 169.1 0.0 0.0 0.0 HOH
4.712
N
O
ALA C:157 C:162 0.0 0.0 E -152.8 167.0 NA NA NA
4v0w 1 P63087 100.0 0.0 X-RAY
2015-03-25 ALA A:157 A:162 0.0 0.0 E -154.6 168.0 0.0 0.0 0.0 HOH
4.734
N
O
ALA C:157 C:162 0.0 0.0 E -155.9 166.7 NA NA NA
4v0x 1 P63087 100.0 0.0 X-RAY
2015-03-25 ALA A:157 A:162 0.0 0.0 E -153.8 160.8 0.0 0.0 0.0 HOH
4.382
HA
O
3egg 1 P62136 90.58 0.0 X-RAY
2010-03-23 ALA A:161 A:162 0.0 0.0 E -152.0 165.2 0.0 0.0 0.0 GOL
HOH
9.555
8.125
O
O
O3
O
ALA B:161 B:162 0.0 0.0 E -154.0 164.5 NA NA NA
3egh 1 P62136 90.58 0.0 X-RAY
2010-03-23 ALA A:161 A:162 0.0 0.0 E -156.8 162.2 0.0 0.0 0.0 GOL
HOH
9.279
4.697
O
N
C1
O
ALA B:161 B:162 0.0 0.0 E -156.1 162.8 NA NA NA
3hvq 1 P62136 90.58 0.0 X-RAY
2010-03-23 ALA A:161 A:162 0.0 0.0 E -154.8 164.1 0.0 0.0 0.0 HOH
4.824
N
O
ALA B:161 B:162 0.0 0.0 E -156.3 163.8 0.0 0.0 0.0 HOH
4.674
N
O
6ghm 1 P62136 90.58 0.0 X-RAY
2019-02-27 ALA A:161 A:162 0.0 0.0 E -158.6 163.4 0.0 0.0 0.0 EDO
HOH
7.701
4.628
O
N
O1
O
ALA B:161 B:162 0.0 0.0 E -155.5 162.5 NA NA NA
3n5u 1 P62136 96.67 0.0 X-RAY
2010-08-11 ALA A:162 A:162 0.0 0.0 E -153.4 159.1 0.0 0.0 0.0
ALA B:162 B:162 0.0 0.0 E -153.3 158.1 0.0 0.0 0.0
6obn 1 P62136 96.67 0.0 X-RAY
2019-09-18 ALA A:167 A:162 0.0 0.0 E -150.6 167.5 0.0 0.0 0.0 HOH
7.090
O
O
ALA B:167 B:162 0.0 0.0 E -150.4 166.7 NA NA NA
6obp 1 P62136 96.67 0.0 X-RAY
2019-09-18 ALA A:167 A:162 0.0 0.0 E -159.8 161.3 0.0 0.0 0.0 HOH
7.316
O
O
6zej 1 P62136,Q4VY12 94.46 0.0 X-RAY
2020-09-30 ALA A:161 D:161 0.0 0.0 E -157.5 170.8 0.0 0.0 0.0 HOH
4.085
HA
O
ALA B:161 A:161 0.0 0.0 E -153.1 173.8 NA NA NA
ALA C:161 F:161 0.0 0.0 E -159.3 165.1 NA NA NA
ALA D:161 I:161 0.0 0.0 E -157.1 168.4 NA NA NA
ALA E:161 L:161 0.0 0.0 E -154.4 172.3 NA NA NA
ALA F:161 O:161 0.0 0.0 E -149.8 163.9 NA NA NA
6zeh 1 P62136,Q13813 96.33 0.0 X-RAY
2020-09-30 ALA A:161 A:162 0.0 0.0 E -151.3 165.9 0.0 0.0 0.0 HOH
4.261
HA
O
ALA C:161 B:162 0.0 0.0 E -157.9 165.0 NA NA NA
3v4y 1 P62136 96.33 0.0 X-RAY
2012-10-31 ALA A:161 A:162 0.0 0.0 E -151.9 170.7 0.0 0.0 0.0 GOL
HOH
6.584
4.316
O
HA
HO1
O
ALA C:161 C:162 0.0 0.0 E -153.2 164.4 NA NA NA
ALA E:161 E:162 0.0 0.0 E -158.9 167.6 NA NA NA
ALA G:161 G:162 0.0 0.0 E -154.6 169.8 NA NA NA
6zei 1 P62136,Q9UQB8 96.32 0.0 X-RAY
2020-09-30 ALA A:161 A:162 0.0 0.0 E -154.3 164.3 0.0 0.0 0.0 HOH
4.318
HA
O
ALA C:161 B:162 0.0 0.0 E -153.8 166.1 NA NA NA
6zeg 1 P62136,Q9UQB8 96.32 0.0 X-RAY
2020-09-30 ALA A:161 A:162 0.0 0.0 E -153.4 164.8 0.0 0.0 0.0 EDO
HOH
8.491
4.308
H
HA
H11
O
ALA C:161 B:162 0.0 0.0 E -156.7 166.1 NA NA NA
3e7a 1 P62136 96.63 0.0 X-RAY
2008-11-04 ALA A:161 A:162 0.0 0.0 E -157.4 161.5 0.0 0.0 0.0 GOL
HOH
7.651
4.636
O
N
O1
O
ALA B:161 B:162 0.0 0.0 E -156.4 164.7 NA NA NA
3e7b 1 P62136 96.63 0.0 X-RAY
2008-11-04 ALA A:161 A:162 0.0 0.0 E -151.3 161.0 0.0 0.0 0.0 GOL
HOH
7.515
4.556
O
N
O1
O
ALA B:161 B:162 0.0 0.0 E -155.0 163.0 NA NA NA
4mov 1 P62136 96.63 0.0 X-RAY
2014-03-26 ALA A:161 A:162 0.0 0.0 E -156.0 167.3 0.0 0.0 0.0 HOH
4.666
N
O
ALA B:161 B:162 0.0 0.0 E -156.5 166.3 NA NA NA
4moy 1 P62136 96.63 0.0 X-RAY
2014-03-26 ALA A:161 A:162 0.0 0.0 E -157.9 164.5 0.0 0.0 0.0 GOL
HOH
7.819
4.849
O
N
O3
O
4mp0 1 P62136 96.63 0.0 X-RAY
2014-03-26 ALA A:161 A:162 0.0 0.0 E -150.2 166.5 0.0 0.0 0.0 GOL
HOH
7.460
4.725
O
N
O3
O
ALA B:161 C:162 0.0 0.0 E -149.3 166.8 NA NA NA
4xpn 1 P62136 96.63 0.0 X-RAY
2015-07-01 ALA A:161 A:162 0.0 0.0 E -154.9 161.7 0.0 0.0 0.0 GOL
HOH
7.736
4.521
O
N
O3
O
ALA C:161 C:162 0.0 0.0 E -156.5 162.8 NA NA NA
5ioh 1 P62136 96.63 0.0 X-RAY
2016-10-05 ALA A:161 A:162 0.0 0.0 E -137.2 164.8 0.0 0.0 0.0 HOH
4.902
N
O
ALA C:161 C:162 0.0 0.0 E -137.0 165.1 NA NA NA
6alz 1 P62136 96.63 0.0 X-RAY
2017-11-29 ALA A:161 A:162 0.0 0.0 E -150.3 164.4 0.0 0.0 0.0 DMS
HOH
7.623
4.635
O
N
C1
O
ALA B:161 B:162 0.0 0.0 E -146.1 169.4 NA NA NA
6czo 1 P62136 96.63 0.0 X-RAY
2019-01-23 ALA A:161 A:162 0.0 0.0 E -145.1 174.8 0.0 0.0 0.0 HOH
4.871
N
O
ALA C:161 C:162 0.0 0.0 E -156.6 164.5 NA NA NA
6dno 1 P62136 96.63 0.0 X-RAY
2019-01-23 ALA A:161 A:162 0.0 0.0 E -152.0 166.9 0.0 0.0 0.0 HOH
4.769
N
O
6zee 1 P62136 96.63 0.0 X-RAY
2020-09-30 ALA A:161 P:162 0.0 0.0 E -146.9 170.8 0.0 0.0 0.0 HOH
4.316
HA
O
ALA B:161 Q:162 0.0 0.0 E -158.4 168.1 0.0 0.0 0.0 HOH
4.235
HA
O
ALA C:161 B:162 0.0 0.0 E -152.3 167.6 0.0 0.0 0.0 HOH
4.439
HA
O
ALA D:161 A:162 0.0 0.0 E -152.3 166.7 0.0 0.0 0.0 16P
EDO
HOH
7.903
8.041
4.374
H
O
HA
H52
HO2
O
ALA E:161 I:162 0.0 0.0 E -150.8 167.6 0.0 0.0 0.0 HOH
4.393
HA
O
ALA F:161 K:162 0.0 0.0 E -153.8 169.8 0.0 0.0 0.0 EDO
GOL
HOH
8.126
9.023
4.468
O
H
HA
HO2
H32
O
6zef 1 P62136 96.63 0.0 X-RAY
2020-09-30 ALA A:161 A:162 0.0 0.0 E -153.8 163.2 0.0 0.0 0.0 EDO
EDO
HOH
6.985
7.454
4.444
O
O
HA
HO1
H11
O
ALA B:161 B:162 0.0 0.0 E -155.0 163.2 NA NA NA
1u32 1 P36873 98.29 0.0 X-RAY
2004-08-17 ALA A:157 A:162 0.0 0.0 E -157.1 168.3 0.0 0.0 0.0 HOH
4.943
N
O
5zt0 1 P62137 97.28 0.0 X-RAY
2019-03-13 ALA A:156 A:162 0.0 0.0 E -138.9 172.2 0.0 0.0 0.0
ALA B:156 B:162 0.0 0.0 E -138.8 170.1 NA NA NA
ALA C:156 C:162 0.0 0.0 E -140.9 171.9 NA NA NA
ALA D:156 D:162 0.0 0.0 E -140.0 168.0 NA NA NA
ALA E:156 E:162 0.0 0.0 E -136.0 169.8 NA NA NA
ALA F:156 F:162 0.0 0.0 E -140.1 170.0 NA NA NA
6obr 1 P62136 96.3 0.0 X-RAY
2019-09-18 ALA A:161 A:162 0.0 0.0 E -153.2 165.0 0.0 0.0 0.0 HOH
4.686
N
O
ALA B:161 B:162 0.0 0.0 E -148.4 165.1 NA NA NA
6obq 1 P62136 96.3 0.0 X-RAY
2019-09-18 ALA A:161 A:162 0.0 0.0 E -149.7 167.4 0.0 0.0 0.0 HOH
4.694
N
O
ALA B:161 B:162 0.0 0.0 E -150.0 168.3 NA NA NA
6obs 1 P62136 96.3 0.0 X-RAY
2019-09-18 ALA A:161 A:162 0.0 0.0 E -154.6 168.0 0.0 0.0 0.0 HOH
4.618
N
O
ALA B:161 B:162 0.0 0.0 E -153.3 169.2 NA NA NA
6obu 1 P62136 96.3 0.0 X-RAY
2019-09-18 ALA A:161 A:162 0.0 0.0 E -151.6 164.5 0.0 0.0 0.0 GOL
HOH
7.614
4.624
O
N
O1
O
ALA B:161 B:162 0.0 0.0 E -154.3 166.3 NA NA NA
7nzm 2 P62139 97.28 0.0 EM
2021-09-29 ALA B:156 B:162 2.0 0.017 E -150.7 166.8 2.0 0.017 0.0
1s70 1 P62140 89.06 0.0 X-RAY
2004-06-22 ALA A:164 A:162 0.0 0.0 E -153.8 172.5 0.0 0.0 0.0 HOH
4.866
N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p36873-f1 1 P36873 100.0 0.0 ALA A:162 A:162 0.0 0.0 E -150.5 163.2
af-p62136-f1 1 P62136 90.66 0.0 ALA A:162 A:162 0.0 0.0 E -146.2 164.5
af-p62140-f1 1 P62140 89.06 0.0 ALA A:161 A:161 0.0 0.0 E -145.8 164.4