Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12288172 . C A CCDS8647.1:NM_002336.2:c.3670Ggt>Tgt_NP_002327.2:p.1224G>C Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 GLY A:597 A:1224 52.0 0.693 S 83.2 -20.7 52.0 0.693 0.0 HOH
 9.190
 O
 O
GLY B:597 B:1224 48.0 0.64 S 68.0 12.6 48.0 0.64 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 GLY A:597 A:1224 52.0 0.693 S 73.1 18.7 52.0 0.693 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 GLY A:599 A:1224 69.0 0.92 S 89.9 0.9 69.0 0.92 0.0 EDO
HOH
 7.096
4.983
 N
N
 O1
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 GLY B:594 B:1224 49.0 0.653 S 68.0 12.7 49.0 0.653 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLY A:595 A:1224 41.0 0.547 S 111.9 -8.2 41.0 0.547 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLY A:595 A:1224 43.0 0.573 S 107.0 -17.3 43.0 0.573 0.0 HOH
 5.714
 O
 O
GLY D:595 B:1224 49.0 0.653 S 103.1 -14.0 49.0 0.653 0.0
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLY A:604 A:1224 55.0 0.733 T 165.5 36.0 55.0 0.733 0.0
GLY B:604 B:1224 59.0 0.787 S 154.4 -10.3 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLY A:604 A:1224 47.0 0.627 T 83.4 40.4 47.0 0.627 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 GLY A:1224 A:1224 55.0 0.733 S 87.7 4.0