Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12288214 . C A CCDS8647.1:NM_002336.2:c.3628Gat>Tat_NP_002327.2:p.1210D>Y Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ASP A:583 A:1210 131.0 0.873 G 50.7 21.8 131.0 0.873 0.0 HOH
 8.216
 O
 O
ASP B:583 B:1210 130.0 0.867 G 58.3 7.3 130.0 0.867 0.0 HOH
 9.464
 O
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ASP A:583 A:1210 125.0 0.833 G 61.1 19.1 125.0 0.833 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ASP A:585 A:1210 143.0 0.953 G 54.0 43.8 143.0 0.953 0.0 HOH
 2.708
 N
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ASP B:580 B:1210 131.0 0.873 G 58.2 7.3 131.0 0.873 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:581 A:1210 141.0 0.94 G 56.5 35.7 141.0 0.94 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:581 A:1210 150.0 1.0 G 53.3 41.1 150.0 1.0 0.0 HOH
 3.535
 N
 O
ASP D:581 B:1210 151.0 1.0 G 55.5 47.8 151.0 1.0 0.0 HOH
 9.303
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:590 A:1210 151.0 1.0 G 43.0 44.2 151.0 1.0 0.0
ASP B:590 B:1210 152.0 1.0 G 43.4 55.0 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:590 A:1210 141.0 0.94 G 51.9 44.1 141.0 0.94 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ASP A:1210 A:1210 146.0 0.973 G 53.8 36.1