Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12288217 . G A CCDS8647.1:NM_002336.2:c.3625Cag>Tag_NP_002327.2:p.1209Q>* Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 GLN A:582 A:1209 160.0 0.889 G -78.8 139.2 160.0 0.889 0.0 HOH
 8.586
 O
 O
GLN B:582 B:1209 153.0 0.85 T -118.5 143.4 153.0 0.85 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 GLN A:582 A:1209 139.0 0.772 S -95.3 125.4 139.0 0.772 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 GLN A:584 A:1209 143.0 0.794 T -96.3 103.8 143.0 0.794 0.0 HOH
 3.588
 CA
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 GLN B:579 B:1209 152.0 0.844 T -118.5 143.4 152.0 0.844 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLN A:580 A:1209 122.0 0.678 S -85.0 98.9 122.0 0.678 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLN A:580 A:1209 162.0 0.9 T -103.1 97.5 162.0 0.9 0.0 HOH
 4.180
 N
 O
GLN D:580 B:1209 105.0 0.583 T -90.0 82.2 105.0 0.583 0.0
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLN A:589 A:1209 107.0 0.594 T -93.4 119.0 107.0 0.594 0.0
GLN B:589 B:1209 144.0 0.8 T -79.0 80.9 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLN A:589 A:1209 134.0 0.744 T -80.2 78.8 134.0 0.744 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 GLN A:1209 A:1209 164.0 0.911 T -109.3 113.9