Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12291373 . G A CCDS8647.1:NM_002336.2:c.3493Caa>Taa_NP_002327.2:p.1165Q>* Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 GLN A:538 A:1165 74.0 0.411 T 51.4 44.9 74.0 0.411 0.0
GLN B:538 B:1165 74.0 0.411 T 56.7 40.2 39.0 0.217 0.194 C:O94907:0.194
 HOH
 3.921
 CG
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 GLN A:538 A:1165 74.0 0.411 T 62.9 54.5 53.0 0.294 0.117 C:O94907:0.117
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 GLN A:540 A:1165 78.0 0.433 T 60.4 41.1 78.0 0.433 0.0 HOH
 2.710
 OE1
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 GLN B:535 B:1165 73.0 0.406 T 56.8 40.2 38.0 0.211 0.195 C:O94907:0.194
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLN A:536 A:1165 71.0 0.394 T 58.5 59.8 71.0 0.394 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLN A:536 A:1165 77.0 0.428 T 58.1 51.7 77.0 0.428 0.0 CL
HOH
 7.150
3.349
 O
NE2
 CL
O
GLN D:536 B:1165 68.0 0.378 T 58.2 37.5 68.0 0.378 0.0
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLN A:545 A:1165 83.0 0.461 T 61.3 31.9 74.0 0.411 0.05 C:O94907:0.05
GLN B:545 B:1165 80.0 0.444 T 33.5 58.0 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLN A:545 A:1165 83.0 0.461 T 61.8 46.2 83.0 0.461 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 GLN A:1165 A:1165 78.0 0.433 T 60.4 41.6