Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12291406 . C A CCDS8647.1:NM_002336.2:c.3460Gaa>Taa_NP_002327.2:p.1154E>* Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 GLU A:527 A:1154 130.0 0.684 T 62.5 -114.4 130.0 0.684 0.0
GLU B:527 B:1154 134.0 0.705 T 65.5 -117.1 134.0 0.705 0.0 HOH
 8.375
 OE1
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 GLU A:527 A:1154 106.0 0.558 T 60.1 -93.3 106.0 0.558 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 GLU A:529 A:1154 110.0 0.579 T 57.1 -117.3 110.0 0.579 0.0 HOH
 2.868
 O
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 GLU B:524 B:1154 133.0 0.7 T 65.5 -117.1 133.0 0.7 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLU A:525 A:1154 106.0 0.558 S 58.5 -115.7 106.0 0.558 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLU A:525 A:1154 73.0 0.384 S -106.5 -88.1 73.0 0.384 0.0 HOH
 6.882
 O
 O
GLU D:525 B:1154 101.0 0.532 S -139.8 -65.3 101.0 0.532 0.0 HOH
 5.011
 CG
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLU A:534 A:1154 111.0 0.584 S -128.8 -74.2 111.0 0.584 0.0
GLU B:534 B:1154 99.0 0.521 S -113.2 -81.9 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLU A:534 A:1154 138.0 0.726 S -112.1 -54.4 138.0 0.726 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 GLU A:1154 A:1154 119.0 0.626 T 51.9 -97.6