Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12291460 . G A CCDS8647.1:NM_002336.2:c.3406Cgg>Tgg_NP_002327.2:p.1136R>W Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ARG A:509 A:1136 66.0 0.293 -78.0 128.6 66.0 0.293 0.0
ARG B:509 B:1136 77.0 0.342 -67.8 123.4 77.0 0.342 0.0 HOH
 3.331
 N
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ARG A:509 A:1136 82.0 0.364 -73.4 116.4 82.0 0.364 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ARG A:511 A:1136 64.0 0.284 -64.7 130.8 64.0 0.284 0.0 CL
HOH
 3.719
2.632
 NH1
O
 CL
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ARG B:506 B:1136 76.0 0.338 -67.8 123.3 76.0 0.338 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:507 A:1136 81.0 0.36 -77.5 93.4 81.0 0.36 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:507 A:1136 69.0 0.307 -76.0 133.9 69.0 0.307 0.0 CL
HOH
 4.930
3.159
 O
NH1
 CL
O
ARG D:507 B:1136 70.0 0.311 -71.7 127.3 70.0 0.311 0.0 HOH
 3.923
 NH1
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:516 A:1136 73.0 0.324 -70.4 118.5 73.0 0.324 0.0
ARG B:516 B:1136 87.0 0.387 -76.3 122.2 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:516 A:1136 83.0 0.369 -57.9 114.4 83.0 0.369 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ARG A:1136 A:1136 69.0 0.307 -60.5 126.6