Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12291462 . T A CCDS8647.1:NM_002336.2:c.3404aAc>aTc_NP_002327.2:p.1135N>I Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ASN A:508 A:1135 111.0 0.694 S 51.9 55.1 111.0 0.694 0.0
ASN B:508 B:1135 92.0 0.575 S 63.9 46.3 92.0 0.575 0.0 HOH
 3.461
 N
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ASN A:508 A:1135 90.0 0.562 65.0 52.5 90.0 0.562 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ASN A:510 A:1135 137.0 0.856 S 59.4 50.2 137.0 0.856 0.0 HOH
 2.556
 OD1
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ASN B:505 B:1135 93.0 0.581 S 63.9 46.3 93.0 0.581 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASN A:506 A:1135 103.0 0.644 61.8 58.1 103.0 0.644 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASN A:506 A:1135 110.0 0.688 61.6 57.2 110.0 0.688 0.0 CL
HOH
 8.278
2.639
 C
O
 CL
O
ASN D:506 B:1135 114.0 0.713 61.9 50.0 114.0 0.713 0.0
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASN A:515 A:1135 104.0 0.65 55.4 50.7 104.0 0.65 0.0
ASN B:515 B:1135 106.0 0.662 59.4 62.5 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASN A:515 A:1135 101.0 0.631 -97.7 71.6 101.0 0.631 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ASN A:1135 A:1135 113.0 0.706 S 52.1 41.4