Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12300309 . C A CCDS8647.1:NM_002336.2:c.3388Gat>Tat_NP_002327.2:p.1130D>Y Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ASP A:503 A:1130 36.0 0.24 E -78.9 153.1 36.0 0.24 0.0
ASP B:503 B:1130 57.0 0.38 E -72.7 155.1 57.0 0.38 0.0 HOH
 7.163
 N
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ASP A:503 A:1130 50.0 0.333 E -75.9 165.6 50.0 0.333 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ASP A:505 A:1130 57.0 0.38 E -60.0 155.1 57.0 0.38 0.0 HOH
 2.816
 OD1
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ASP B:500 B:1130 56.0 0.373 E -72.6 155.1 56.0 0.373 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:501 A:1130 38.0 0.253 E -86.4 161.5 38.0 0.253 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:501 A:1130 41.0 0.273 E -71.5 161.4 41.0 0.273 0.0 HOH
 3.659
 CB
 O
ASP D:501 B:1130 40.0 0.267 E -71.8 162.0 40.0 0.267 0.0
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:510 A:1130 60.0 0.4 E -69.1 143.1 60.0 0.4 0.0
ASP B:510 B:1130 54.0 0.36 E -58.1 143.7 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:510 A:1130 62.0 0.413 E -83.8 161.4 62.0 0.413 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ASP A:1130 A:1130 37.0 0.247 E -69.2 157.9