Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12300353 . T A CCDS8647.1:NM_002336.2:c.3344aAg>aTg_NP_002327.2:p.1115K>M Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 LYS A:488 A:1115 44.0 0.22 E -122.8 150.5 44.0 0.22 0.0
LYS B:488 B:1115 47.0 0.235 E -111.1 148.6 47.0 0.235 0.0 HOH
 7.656
 O
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 LYS A:488 A:1115 56.0 0.28 E -123.0 141.9 56.0 0.28 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 LYS A:490 A:1115 64.0 0.32 E -121.4 148.8 64.0 0.32 0.0 CL
HOH
 7.590
3.070
 O
NZ
 CL
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 LYS B:485 B:1115 49.0 0.245 E -111.1 148.6 49.0 0.245 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 LYS A:486 A:1115 71.0 0.355 E -123.9 147.2 71.0 0.355 0.0 HOH
 9.441
 O
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 LYS A:486 A:1115 57.0 0.285 E -125.1 137.4 57.0 0.285 0.0 HOH
 2.670
 NZ
 O
LYS D:486 B:1115 53.0 0.265 E -126.9 141.0 53.0 0.265 0.0 HOH
 7.219
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 LYS A:495 A:1115 48.0 0.24 E -124.2 152.7 48.0 0.24 0.0
LYS B:495 B:1115 41.0 0.205 E -137.5 146.1 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 LYS A:495 A:1115 59.0 0.295 E -123.8 155.6 59.0 0.295 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 LYS A:1115 A:1115 49.0 0.245 E -112.1 143.2