Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12300361 . C A CCDS8647.1:NM_002336.2:c.3336agG>agT_NP_002327.2:p.1112R>S Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ARG A:485 A:1112 217.0 0.964 T -59.6 -46.7 217.0 0.964 0.0
ARG B:485 B:1112 186.0 0.827 T -61.6 -41.1 186.0 0.827 0.0 HOH
 9.248
 N
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ARG A:485 A:1112 193.0 0.858 T -72.2 -55.3 193.0 0.858 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ARG A:487 A:1112 146.0 0.649 T -65.8 -43.8 146.0 0.649 0.0 HOH
 3.050
 N
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ARG B:482 B:1112 185.0 0.822 T -61.7 -41.1 185.0 0.822 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:483 A:1112 95.0 NA T -61.7 -47.1 95.0 NA NA
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:483 A:1112 144.0 0.64 T -68.9 -34.8 144.0 0.64 0.0 HOH
 3.151
 N
 O
ARG D:483 B:1112 127.0 0.564 T -69.9 -36.9 127.0 0.564 0.0 HOH
 4.632
 N
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:492 A:1112 179.0 0.796 T -63.5 -47.2 179.0 0.796 0.0
ARG B:492 B:1112 215.0 0.956 T -58.7 -39.4 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:492 A:1112 186.0 0.827 T -69.4 -57.7 186.0 0.827 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ARG A:1112 A:1112 152.0 0.676 T -69.5 -47.7