Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12300420 . G A CCDS8647.1:NM_002336.2:c.3277Cgg>Tgg_NP_002327.2:p.1093R>W Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ARG A:466 A:1093 94.0 0.418 -74.5 146.5 94.0 0.418 0.0
ARG B:466 B:1093 85.0 0.378 -60.2 143.6 85.0 0.378 0.0 HOH
 6.792
 NH2
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ARG A:466 A:1093 92.0 0.409 -74.5 140.9 92.0 0.409 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ARG A:468 A:1093 93.0 0.413 -66.2 133.7 93.0 0.413 0.0 EDO
HOH
 8.593
2.746
 N
NH1
 C2
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ARG B:463 B:1093 86.0 0.382 -60.2 143.6 86.0 0.382 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:464 A:1093 84.0 0.373 -68.8 114.4 84.0 0.373 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:464 A:1093 91.0 0.404 -67.2 131.2 91.0 0.404 0.0 HOH
 4.008
 NH2
 O
ARG D:464 B:1093 87.0 0.387 -66.7 129.4 87.0 0.387 0.0
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:473 A:1093 93.0 0.413 -67.1 137.4 93.0 0.413 0.0
ARG B:473 B:1093 94.0 0.418 -76.3 134.3 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:473 A:1093 95.0 0.422 -65.6 133.6 95.0 0.422 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ARG A:1093 A:1093 100.0 0.444 -71.0 126.9