Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12300473 . T A CCDS8647.1:NM_002336.2:c.3224aAt>aTt_NP_002327.2:p.1075N>I Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ASN A:448 A:1075 0.0 0.0 E -119.8 95.3 0.0 0.0 0.0
ASN B:448 B:1075 0.0 0.0 E -118.7 94.8 0.0 0.0 0.0 HOH
 6.086
 ND2
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ASN A:448 A:1075 0.0 0.0 E -98.2 96.5 0.0 0.0 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ASN A:450 A:1075 0.0 0.0 E -126.2 102.6 0.0 0.0 0.0 HOH
 3.879
 ND2
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ASN B:445 B:1075 0.0 0.0 E -118.8 94.8 0.0 0.0 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASN A:446 A:1075 1.0 0.006 E -128.0 104.1 1.0 0.006 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASN A:446 A:1075 1.0 0.006 E -119.4 97.8 1.0 0.006 0.0 HOH
 4.416
 ND2
 O
ASN D:446 B:1075 0.0 0.0 E -117.6 95.9 0.0 0.0 0.0 HOH
 9.142
 OD1
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASN A:455 A:1075 1.0 0.006 E -111.3 101.1 1.0 0.006 0.0
ASN B:455 B:1075 0.0 0.0 E -130.7 95.5 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASN A:455 A:1075 0.0 0.0 E -123.8 94.5 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ASN A:1075 A:1075 0.0 0.0 E -109.2 98.8