Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12301898 . C A CCDS8647.1:NM_002336.2:c.3184Gtt>Ttt_NP_002327.2:p.1062V>F Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ILE A:435 A:1062 1.0 0.006 E -150.9 134.1 1.0 0.006 0.0 GOL
HOH
 3.984
8.907
 O
O
 O3
O
ILE B:435 B:1062 1.0 0.006 E -144.4 136.1 1.0 0.006 0.0 HOH
 8.481
 O
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ILE A:435 A:1062 1.0 0.006 E -149.2 129.4 1.0 0.006 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 VAL A:437 A:1062 1.0 0.006 E -143.9 141.6 1.0 0.006 0.0 CL
CA
HOH
 6.981
4.538
2.701
 O
O
O
 CL
CA
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ILE B:432 B:1062 1.0 0.006 E -144.4 136.0 1.0 0.006 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 VAL A:433 A:1062 3.0 0.019 E -144.0 142.8 3.0 0.019 0.0 CA
HOH
 5.240
3.052
 O
O
 CA
O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 VAL A:433 A:1062 1.0 0.006 E -157.2 141.0 1.0 0.006 0.0 HOH
 4.723
 O
 O
VAL D:433 B:1062 4.0 0.026 E -157.5 143.3 4.0 0.026 0.0 HOH
 3.641
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ILE A:442 A:1062 3.0 0.017 E -142.6 140.4 3.0 0.017 0.0
ILE B:442 B:1062 4.0 0.023 E -149.5 140.6 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ILE A:442 A:1062 1.0 0.006 E -148.1 141.0 1.0 0.006 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 VAL A:1062 A:1062 1.0 0.006 E -144.8 136.6