Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12301904 . G A CCDS8647.1:NM_002336.2:c.3178Cga>Tga_NP_002327.2:p.1060R>* Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ARG A:433 A:1060 20.0 0.089 E -130.0 -85.3 20.0 0.089 0.0 GOL
HOH
 8.682
8.084
 O
NH2
 C3
O
ARG B:433 B:1060 27.0 0.12 E -121.5 -89.5 27.0 0.12 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ARG A:433 A:1060 23.0 0.102 E -126.6 -79.6 23.0 0.102 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ARG A:435 A:1060 25.0 0.111 E -127.6 -86.6 25.0 0.111 0.0 CA
HOH
 8.803
3.363
 O
NH2
 CA
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ARG B:430 B:1060 26.0 0.116 E -121.5 -89.5 26.0 0.116 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:431 A:1060 33.0 0.147 E -116.4 -88.0 33.0 0.147 0.0 CA
HOH
 9.973
7.557
 O
O
 CA
O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:431 A:1060 26.0 0.116 E -129.4 -93.8 26.0 0.116 0.0 HOH
 3.314
 NE
 O
ARG D:431 B:1060 23.0 0.102 E -127.1 -94.2 23.0 0.102 0.0 HOH
 6.488
 NE
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:440 A:1060 24.0 0.107 E -119.4 -79.8 24.0 0.107 0.0
ARG B:440 B:1060 27.0 0.12 E -124.0 -88.6 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:440 A:1060 25.0 0.111 E -131.0 -86.0 25.0 0.111 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ARG A:1060 A:1060 26.0 0.116 E -131.3 -93.5