Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12301952 . C A CCDS8647.1:NM_002336.2:c.3130Gat>Tat_NP_002327.2:p.1044D>Y Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ASP A:417 A:1044 98.0 0.653 T -103.5 19.0 98.0 0.653 0.0 NAG
NAG
 8.069
7.342
 C
O
 O6
C8
ASP B:417 B:1044 74.0 0.493 T -88.3 -17.9 74.0 0.493 0.0 NAG
NAG
 8.606
7.786
 OD1
O
 O6
C8
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ASP A:417 A:1044 79.0 0.527 S -70.6 -29.8 79.0 0.527 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ASP A:419 A:1044 94.0 0.627 T -85.2 3.7 94.0 0.627 0.0 NAG
NAG
HOH
 8.517
7.492
2.883
 C
O
OD2
 O6
C8
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ASP B:414 B:1044 76.0 0.507 T -88.2 -18.1 76.0 0.507 0.0 NAG
NAG
 8.606
7.787
 OD1
O
 O6
C8
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:415 A:1044 86.0 0.573 T -80.4 -3.8 86.0 0.573 0.0 NAG
NAG
 8.301
7.476
 C
O
 O6
C8
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:415 A:1044 80.0 0.533 T -87.9 2.7 80.0 0.533 0.0 NAG
NAG
HOH
 8.783
7.855
2.362
 C
O
OD2
 O6
C8
O
ASP D:415 B:1044 94.0 0.627 T -86.1 5.0 94.0 0.627 0.0 NAG
NAG
 8.658
7.814
 C
O
 O6
C8
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:424 A:1044 98.0 0.653 S -72.8 -30.5 98.0 0.653 0.0
ASP B:424 B:1044 93.0 0.62 T -71.4 -32.3 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:424 A:1044 87.0 0.58 T -81.0 4.4 87.0 0.58 0.0 NAG
NAG
 8.825
8.729
 C
O
 O6
O7

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ASP A:1044 A:1044 78.0 0.52 T -93.7 -2.9