Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12302005 . C A CCDS8647.1:NM_002336.2:c.3077cGc>cTc_NP_002327.2:p.1026R>L Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ARG A:399 A:1026 53.0 0.236 T 74.5 48.2 53.0 0.236 0.0 HOH
 8.594
 NH2
 O
ARG B:399 B:1026 60.0 0.267 T 59.0 43.6 60.0 0.267 0.0 HOH
 6.600
 N
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ARG A:399 A:1026 62.0 0.276 T 64.9 40.7 62.0 0.276 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ARG A:401 A:1026 54.0 0.24 T 72.9 47.7 54.0 0.24 0.0 HOH
 2.796
 O
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ARG B:396 B:1026 56.0 0.249 T 59.0 43.6 56.0 0.249 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:397 A:1026 58.0 0.258 T 54.8 46.4 58.0 0.258 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:397 A:1026 52.0 0.231 T 60.6 42.3 52.0 0.231 0.0 HOH
 3.844
 CG
 O
ARG D:397 B:1026 55.0 0.244 T 60.9 41.4 55.0 0.244 0.0 HOH
 7.530
 N
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:406 A:1026 61.0 0.271 T 63.2 37.1 61.0 0.271 0.0
ARG B:406 B:1026 56.0 0.249 T 65.2 39.0 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:406 A:1026 51.0 0.227 T 68.3 38.9 51.0 0.227 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ARG A:1026 A:1026 51.0 0.227 T 68.8 41.9