Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12303811 . G A CCDS8647.1:NM_002336.2:c.2953Cga>Tga_NP_002327.2:p.985R>* Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ARG A:358 A:985 184.0 0.818 T -58.9 -48.2 184.0 0.818 0.0
ARG B:358 B:985 191.0 0.849 T -91.3 -52.3 191.0 0.849 0.0 GOL
 3.000
 NH2
 O1
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ARG A:358 A:985 168.0 0.747 T -73.1 -58.9 168.0 0.747 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ARG A:360 A:985 165.0 0.733 T -69.4 -47.5 165.0 0.733 0.0 HOH
 3.363
 CD
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ARG B:355 B:985 191.0 0.849 T -91.3 -52.2 191.0 0.849 0.0 GOL
 3.001
 NH2
 O1
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:356 A:985 58.0 NA T -61.5 -59.2 58.0 NA NA
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ARG A:356 A:985 148.0 0.658 T -71.6 -42.5 148.0 0.658 0.0 HOH
 7.532
 N
 O
ARG D:356 B:985 116.0 0.516 T -79.9 -43.4 115.0 0.511 0.005 B:None:0.004
 HOH
 4.757
 CA
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:365 A:985 168.0 0.747 T 70.6 -45.8 168.0 0.747 0.0
ARG B:365 B:985 157.0 0.698 T -69.9 130.4 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ARG A:365 A:985 120.0 0.533 T -91.5 125.8 120.0 0.533 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ARG A:985 A:985 194.0 0.862 T -106.6 -27.7