Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12303924 . A C CCDS8647.1:NM_002336.2:c.2840aTg>aGg_NP_002327.2:p.947M>R Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 MET A:320 A:947 22.0 0.119 E -129.8 146.3 22.0 0.119 0.0
MET B:320 B:947 6.0 0.032 E -138.9 140.3 6.0 0.032 0.0 HOH
 5.515
 SD
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 MET A:320 A:947 4.0 0.022 E -134.0 160.0 4.0 0.022 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 MET A:322 A:947 21.0 0.114 E -132.3 153.9 21.0 0.114 0.0 HOH
 3.271
 CA
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 MET B:317 B:947 6.0 0.032 E -138.9 140.3 6.0 0.032 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 MET A:318 A:947 14.0 0.076 E -106.2 146.5 14.0 0.076 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 MET A:318 A:947 13.0 0.07 E -145.9 135.7 13.0 0.07 0.0 CL
HOH
 7.960
3.379
 CE
CA
 CL
O
MET D:318 B:947 20.0 0.108 E -151.2 138.1 20.0 0.108 0.0 HOH
 9.828
 N
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 MET A:327 A:947 12.0 0.065 E -153.2 139.0 12.0 0.065 0.0
MET B:327 B:947 20.0 0.108 E -124.4 145.4 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 MET A:327 A:947 14.0 0.076 E -130.4 152.6 14.0 0.076 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 MET A:947 A:947 15.0 0.081 E -135.2 152.5