Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12311868 . T A CCDS8647.1:NM_002336.2:c.2686Agc>Tgc_NP_002327.2:p.896S>C Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 SER A:269 A:896 57.0 0.496 H -145.5 29.5 57.0 0.496 0.0
SER B:269 B:896 82.0 0.713 G 60.5 25.1 82.0 0.713 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 SER A:269 A:896 89.0 0.774 G 60.2 26.4 89.0 0.774 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 SER A:271 A:896 45.0 0.391 T -127.5 19.6 45.0 0.391 0.0 HOH
 2.822
 OG
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 SER B:266 B:896 82.0 0.713 G 60.6 25.0 82.0 0.713 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 SER A:267 A:896 41.0 0.357 H -137.0 19.2 41.0 0.357 0.0 HOH
 8.427
 C
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 SER A:267 A:896 90.0 0.783 G 65.7 30.2 90.0 0.783 0.0 HOH
 8.314
 C
 O
SER D:267 B:896 35.0 0.304 H -142.9 16.3 35.0 0.304 0.0 HOH
 9.653
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 SER A:276 A:896 102.0 0.887 G 58.6 47.9 102.0 0.887 0.0
SER B:276 B:896 94.0 0.817 G 60.0 28.0 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 SER A:276 A:896 91.0 0.791 G 56.1 26.9 91.0 0.791 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 SER A:896 A:896 48.0 0.417 T -167.4 17.8