Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12311885 . C A CCDS8647.1:NM_002336.2:c.2669tGg>tTg_NP_002327.2:p.890W>L Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 TRP A:263 A:890 167.0 0.655 -131.4 159.2 167.0 0.655 0.0
TRP B:263 B:890 164.0 0.643 -165.8 155.5 164.0 0.643 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 TRP A:263 A:890 163.0 0.639 -163.4 150.8 163.0 0.639 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 TRP A:265 A:890 172.0 0.675 -156.9 160.4 172.0 0.675 0.0 HOH
 2.817
 O
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 TRP B:260 B:890 164.0 0.643 -165.8 155.5 164.0 0.643 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 TRP A:261 A:890 143.0 0.561 -167.6 142.7 143.0 0.561 0.0
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 TRP A:261 A:890 164.0 0.643 -166.1 152.3 164.0 0.643 0.0 HOH
 4.876
 N
 O
TRP D:261 B:890 161.0 0.631 -165.4 154.0 161.0 0.631 0.0 CL
HOH
 3.307
6.629
 O
N
 CL
O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 TRP A:270 A:890 151.0 0.592 -168.0 137.9 151.0 0.592 0.0
TRP B:270 B:890 156.0 0.612 -134.1 132.2 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 TRP A:270 A:890 174.0 0.682 -156.5 146.5 174.0 0.682 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 TRP A:890 A:890 170.0 0.667 -157.4 146.7