Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12312728 . G A CCDS8647.1:NM_002336.2:c.2450tCt>tTt_NP_002327.2:p.817S>F Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 SER A:190 A:817 0.0 0.0 E -161.8 149.7 0.0 0.0 0.0 HOH
 6.900
 O
 O
SER B:190 B:817 0.0 0.0 E -150.2 153.4 0.0 0.0 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 SER A:190 A:817 0.0 0.0 E -146.2 144.0 0.0 0.0 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 SER A:192 A:817 1.0 0.009 E -136.5 161.2 1.0 0.009 0.0 CL
HOH
 9.855
3.027
 O
OG
 CL
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 SER B:187 B:817 0.0 0.0 E -150.2 153.3 0.0 0.0 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 SER A:188 A:817 2.0 0.017 E -143.6 155.2 2.0 0.017 0.0 HOH
 8.971
 OG
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 SER A:188 A:817 0.0 0.0 E -158.1 161.9 0.0 0.0 0.0
SER D:188 B:817 1.0 0.009 E -151.6 147.3 1.0 0.009 0.0 HOH
 8.439
 N
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 SER A:197 A:817 0.0 0.0 E -142.1 165.3 0.0 0.0 0.0
SER B:197 B:817 0.0 0.0 E -147.4 151.4 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 SER A:197 A:817 1.0 0.009 E -145.8 148.9 1.0 0.009 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 SER A:817 A:817 0.0 0.0 E -145.4 141.5