Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12312886 . C A CCDS8647.1:NM_002336.2:c.2292tgG>tgT_NP_002327.2:p.764W>C Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 TRP A:137 A:764 0.0 0.0 E -150.2 151.9 0.0 0.0 0.0 HOH
 8.233
 CH2
 O
TRP B:137 B:764 0.0 0.0 E -150.2 155.5 0.0 0.0 0.0 HOH
 6.439
 CZ2
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 TRP A:137 A:764 0.0 0.0 E -143.6 148.3 0.0 0.0 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 TRP A:139 A:764 0.0 0.0 E -151.0 157.7 0.0 0.0 0.0 EDO
HOH
 7.890
6.266
 CZ2
CH2
 O2
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 TRP B:134 B:764 0.0 0.0 E -150.2 155.5 0.0 0.0 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 TRP A:135 A:764 0.0 0.0 E -150.2 171.0 0.0 0.0 0.0 HOH
 6.757
 CZ2
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 TRP A:135 A:764 0.0 0.0 E -146.3 154.1 0.0 0.0 0.0 HOH
 6.156
 NE1
 O
TRP D:135 B:764 0.0 0.0 E -150.6 155.5 0.0 0.0 0.0 HOH
 6.440
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 TRP A:144 A:764 0.0 0.0 E -144.7 148.3 0.0 0.0 0.0
TRP B:144 B:764 0.0 0.0 E -152.7 169.6 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 TRP A:144 A:764 0.0 0.0 E -146.2 159.1 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 TRP A:764 A:764 0.0 0.0 E -144.7 160.1