Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12315188 . G A CCDS8647.1:NM_002336.2:c.2218Caa>Taa_NP_002327.2:p.740Q>* Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 GLN A:113 A:740 32.0 0.178 E -153.0 147.4 32.0 0.178 0.0 HOH
 3.087
 NE2
 O
GLN B:113 B:740 39.0 0.217 E -149.2 148.0 39.0 0.217 0.0
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 GLN A:113 A:740 41.0 0.228 E -145.5 137.8 41.0 0.228 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 GLN A:115 A:740 38.0 0.211 E -144.7 146.9 38.0 0.211 0.0 EDO
HOH
 9.337
2.882
 OE1
NE2
 C1
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 GLN B:110 B:740 41.0 0.228 E -149.2 148.0 41.0 0.228 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLN A:111 A:740 39.0 0.217 E -138.2 142.8 39.0 0.217 0.0 HOH
 3.411
 NE2
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLN A:111 A:740 34.0 0.189 E -140.2 146.8 34.0 0.189 0.0 HOH
 3.081
 NE2
 O
GLN D:111 B:740 34.0 0.189 E -142.8 146.0 34.0 0.189 0.0 CL
HOH
 7.899
3.576
 C
NE2
 CL
O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLN A:120 A:740 42.0 0.233 E -142.1 152.8 42.0 0.233 0.0
GLN B:120 B:740 31.0 0.172 E -137.4 143.9 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLN A:120 A:740 39.0 0.217 E -143.5 146.4 39.0 0.217 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 GLN A:740 A:740 41.0 0.228 E -142.0 146.1