Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12315203 . C A CCDS8647.1:NM_002336.2:c.2203Gat>Tat_NP_002327.2:p.735D>Y Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ASP A:108 A:735 71.0 0.473 T -92.3 -0.7 71.0 0.473 0.0 HOH
 5.029
 N
 O
ASP B:108 B:735 67.0 0.447 T -89.8 -5.9 67.0 0.447 0.0 HOH
 3.992
 CB
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ASP A:108 A:735 69.0 0.46 S -76.1 -25.5 69.0 0.46 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ASP A:110 A:735 64.0 0.427 T -91.1 8.2 64.0 0.427 0.0 HOH
 3.058
 OD1
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ASP B:105 B:735 67.0 0.447 T -89.8 -6.0 67.0 0.447 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:106 A:735 73.0 0.487 S -61.5 -38.4 73.0 0.487 0.0 HOH
 9.319
 OD2
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ASP A:106 A:735 64.0 0.427 T -92.0 -7.9 64.0 0.427 0.0 HOH
 3.945
 N
 O
ASP D:106 B:735 66.0 0.44 T -97.2 -6.2 66.0 0.44 0.0 HOH
 3.420
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:115 A:735 61.0 0.407 T -75.5 -16.6 61.0 0.407 0.0
ASP B:115 B:735 66.0 0.44 T -75.2 -22.3 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ASP A:115 A:735 65.0 0.433 T -96.0 5.2 65.0 0.433 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ASP A:735 A:735 65.0 0.433 T -99.9 10.8