Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12315260 . C A CCDS8647.1:NM_002336.2:c.2146Ggg>Tgg_NP_002327.2:p.716G>W Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 GLY A:89 A:716 0.0 0.0 T -75.8 -5.3 0.0 0.0 0.0 HOH
 8.897
 O
 O
GLY B:89 B:716 0.0 0.0 T -80.2 -1.1 0.0 0.0 0.0 HOH
 8.648
 O
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 GLY A:89 A:716 1.0 0.013 T -75.3 -11.5 1.0 0.013 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 GLY A:91 A:716 2.0 0.027 T -80.4 -14.1 2.0 0.027 0.0 HOH
 2.953
 O
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 GLY B:86 B:716 1.0 0.013 T -80.2 -1.0 1.0 0.013 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLY A:87 A:716 1.0 0.013 T -75.3 -4.6 1.0 0.013 0.0 HOH
 3.649
 O
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 GLY A:87 A:716 0.0 0.0 T -85.2 -0.9 0.0 0.0 0.0 HOH
 3.265
 O
 O
GLY D:87 B:716 2.0 0.027 T -85.3 0.5 2.0 0.027 0.0 HOH
 9.345
 N
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLY A:96 A:716 1.0 0.013 T -78.3 -14.7 1.0 0.013 0.0
GLY B:96 B:716 2.0 0.027 T -77.4 -1.7 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 GLY A:96 A:716 0.0 0.0 T -77.2 -9.2 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 GLY A:716 A:716 2.0 0.027 T -77.0 -11.7