Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12315264 . C A CCDS8647.1:NM_002336.2:c.2142tgG>tgT_NP_002327.2:p.714W>C Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 TRP A:87 A:714 27.0 0.106 T -72.1 -21.5 27.0 0.106 0.0 HOH
 3.730
 CZ3
 O
TRP B:87 B:714 26.0 0.102 T -66.9 -13.9 26.0 0.102 0.0 HOH
 7.478
 CA
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 TRP A:87 A:714 25.0 0.098 T -65.5 -33.5 25.0 0.098 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 TRP A:89 A:714 23.0 0.09 T -78.8 -8.3 23.0 0.09 0.0 HOH
 3.436
 CZ2
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 TRP B:84 B:714 25.0 0.098 T -66.9 -13.9 25.0 0.098 0.0
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 TRP A:85 A:714 20.0 0.078 T -81.5 -7.9 20.0 0.078 0.0 HOH
 9.694
 C
 O
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 TRP A:85 A:714 24.0 0.094 T -71.5 -18.0 24.0 0.094 0.0 HOH
 3.264
 CZ2
 O
TRP D:85 B:714 25.0 0.098 T -79.5 -11.5 25.0 0.098 0.0 CL
HOH
 8.706
3.450
 NE1
CZ3
 CL
O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 TRP A:94 A:714 17.0 0.067 T -78.2 -18.2 17.0 0.067 0.0
TRP B:94 B:714 26.0 0.102 T -78.0 -9.9 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 TRP A:94 A:714 21.0 0.082 T -79.5 -0.9 21.0 0.082 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 TRP A:714 A:714 20.0 0.078 T -67.5 -14.3