Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12317217 . A C CCDS8647.1:NM_002336.2:c.2042aTa>aGa_NP_002327.2:p.681I>R Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ILE A:54 A:681 19.0 0.109 T -77.0 -13.2 4.0 0.023 0.086 C:O94907:0.086
 HOH
 4.776
 O
 O
ILE B:54 B:681 42.0 0.24 T -81.5 -1.2 11.0 0.063 0.177 C:O94907:0.177
 HOH
 4.372
 O
 O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ILE A:54 A:681 42.0 0.24 T -74.5 -15.5 11.0 0.063 0.177 C:O94907:0.177
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ILE A:56 A:681 7.0 0.04 T -77.1 -16.6 7.0 0.04 0.0 HOH
 5.289
 CD1
 O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ILE B:51 B:681 42.0 0.24 T -81.4 -1.3 11.0 0.063 0.177 C:O94907:0.177
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ILE A:52 A:681 32.0 0.183 T -80.7 -43.5 5.0 0.029 0.154 B:None:0.154
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ILE A:52 A:681 16.0 0.091 T -67.5 -31.5 0.0 0.0 0.091 B:None:0.091
 HOH
 5.540
 CG2
 O
ILE D:52 B:681 12.0 0.069 T -69.3 -36.3 0.0 0.0 0.069 C:None:0.069
 HOH
 3.717
 O
 O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ILE A:61 A:681 30.0 0.171 T -100.7 -14.3 3.0 0.017 0.154 C:O94907:0.154
ILE B:61 B:681 14.0 0.08 T -79.9 -9.9 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ILE A:61 A:681 41.0 0.234 T -67.1 -13.9 41.0 0.234 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ILE A:681 A:681 21.0 0.12 T -77.6 -19.1