Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 12317233 . T A CCDS8647.1:NM_002336.2:c.2026Att>Ttt_NP_002327.2:p.676I>F Homo sapiens LDL receptor related protein 6 (LRP6), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3s2k 1 O75581 99.84 0.0 X-RAY
 2011-11-02 ILE A:49 A:676 0.0 0.0 E -113.1 144.3 0.0 0.0 0.0 NAG
 9.690
 N
 C6
ILE B:49 B:676 0.0 0.0 E -118.3 140.2 0.0 0.0 0.0 NAG
HOH
 9.686
6.603
 N
N
 O6
O
5fww 1 O75581 99.84 0.0 X-RAY
 2016-07-20 ILE A:49 A:676 1.0 0.006 E -122.4 140.2 1.0 0.006 0.0
4a0p 1 O75581 100.0 0.0 X-RAY
 2011-10-26 ILE A:51 A:676 0.0 0.0 E -103.7 142.9 0.0 0.0 0.0 NAG
HOH
 9.034
6.849
 N
N
 C6
O
5gje 2 O75581 99.84 0.0 EM
 2017-01-18 ILE B:46 B:676 0.0 0.0 E -118.3 140.1 0.0 0.0 0.0 NAG
 9.685
 N
 O6
6h16 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ILE A:47 A:676 0.0 0.0 E -112.6 150.0 0.0 0.0 0.0 NAG
 8.479
 N
 O7
6h15 1 O75581 100.0 0.0 X-RAY
 2019-01-30 ILE A:47 A:676 4.0 0.023 E -114.8 153.9 4.0 0.023 0.0 NAG
HOH
 9.457
9.758
 N
N
 C6
O
ILE D:47 B:676 1.0 0.006 E -119.6 150.9 1.0 0.006 0.0 NAG
HOH
 9.511
7.502
 N
CD1
 C6
O
3s8v 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ILE A:56 A:676 0.0 0.0 E -106.2 150.3 0.0 0.0 0.0
ILE B:56 B:676 0.0 0.0 E -109.7 143.9 NA NA NA
3s8z 1 O75581 99.84 0.0 X-RAY
 2011-10-26 ILE A:56 A:676 0.0 0.0 E -115.1 150.6 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75581-f1 1 O75581 100.0 0.0 ILE A:676 A:676 3.0 0.017 E -108.4 148.9