Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13828696 | . | C | A | CCDS8662.1:NM_000834.3:c.1108Gag>Tag_NP_000825.2:p.370E>* | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | GLU | B:370 | B:370 | 84.0 | NA | T | -103.4 | 28.2 | 84.0 | NA | NA | ||||||
| GLU | D:370 | D:370 | 84.0 | NA | T | -91.2 | 4.8 | 84.0 | NA | NA | |||||||||||||
| 6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | GLU | B:401 | B:370 | 143.0 | 0.753 | T | -73.7 | 2.3 | 143.0 | 0.753 | 0.0 | ||||||
| GLU | D:401 | D:370 | 143.0 | 0.753 | T | -73.6 | 2.2 | 143.0 | 0.753 | 0.0 | |||||||||||||
| 5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:345 | B:370 | 78.0 | NA | T | -65.6 | -3.7 | 78.0 | NA | NA | ||||||
| GLU | D:345 | D:370 | 79.0 | NA | T | -65.6 | -3.6 | 79.0 | NA | NA | |||||||||||||
| 5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:345 | B:370 | 87.0 | NA | T | -82.8 | 5.3 | 87.0 | NA | NA | ||||||
| GLU | D:345 | D:370 | 86.0 | NA | T | -82.8 | 5.3 | 86.0 | NA | NA | |||||||||||||
| 5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:345 | B:370 | 86.0 | NA | T | -83.0 | 5.1 | 86.0 | NA | NA | ||||||
| GLU | D:345 | D:370 | 85.0 | NA | T | -83.1 | 5.1 | 85.0 | NA | NA | |||||||||||||
| 5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | GLU | B:345 | B:370 | 84.0 | NA | T | -81.8 | 5.9 | 84.0 | NA | NA | ||||||
| GLU | D:345 | D:370 | 84.0 | NA | T | -81.9 | 6.0 | 84.0 | NA | NA | |||||||||||||
| 5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:345 | B:370 | 85.0 | NA | S | -84.2 | 6.6 | 85.0 | NA | NA | ||||||
| GLU | D:345 | D:370 | 86.0 | NA | S | -84.4 | 6.7 | 86.0 | NA | NA | |||||||||||||
| 6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:401 | B:370 | 73.0 | NA | T | -69.1 | 11.8 | 73.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 71.0 | NA | T | -69.1 | 11.8 | 71.0 | NA | NA | |||||||||||||
| 6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:401 | B:370 | 70.0 | NA | S | -65.9 | 170.2 | 70.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 70.0 | NA | S | -66.0 | 170.1 | 70.0 | NA | NA | |||||||||||||
| 6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:401 | B:370 | 86.0 | NA | T | -89.8 | 28.8 | 86.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 84.0 | NA | T | -89.8 | 28.7 | 84.0 | NA | NA | |||||||||||||
| 6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:401 | B:370 | 91.0 | 0.479 | S | -145.7 | 2.9 | 91.0 | 0.479 | 0.0 | ||||||
| GLU | D:401 | D:370 | 93.0 | 0.489 | S | -145.7 | 2.9 | 93.0 | 0.489 | 0.0 | |||||||||||||
| 6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:401 | B:370 | 49.0 | NA | T | -74.9 | 10.6 | 49.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 73.0 | NA | T | -106.7 | 31.4 | 73.0 | NA | NA | |||||||||||||
| 6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:401 | B:370 | 142.0 | 0.747 | T | -90.5 | 27.4 | 142.0 | 0.747 | 0.0 | ||||||
| GLU | D:401 | D:370 | 144.0 | 0.758 | T | -90.5 | 27.4 | 144.0 | 0.758 | 0.0 | |||||||||||||
| 6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:401 | B:370 | 57.0 | NA | T | -138.5 | 38.7 | 57.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 133.0 | 0.7 | T | -96.1 | 7.6 | 133.0 | 0.7 | 0.0 | |||||||||||||
| 6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:401 | B:370 | 84.0 | NA | T | -83.5 | 20.1 | 84.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 86.0 | NA | T | -83.4 | 20.0 | 86.0 | NA | NA | |||||||||||||
| 6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:401 | B:370 | 88.0 | NA | T | -80.2 | 15.3 | 88.0 | NA | NA | ||||||
| GLU | D:401 | D:370 | 87.0 | NA | T | -80.2 | 15.3 | 87.0 | NA | NA | |||||||||||||
| 4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | GLU | B:344 | B:370 | 77.0 | NA | T | -88.8 | 11.0 | 77.0 | NA | NA | ||||||
| GLU | D:344 | D:370 | 86.0 | NA | T | -86.4 | 7.3 | 86.0 | NA | NA | |||||||||||||
| 6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | GLU | B:337 | B:370 | 79.0 | NA | S | -94.5 | 4.8 | 79.0 | NA | NA | ||||||
| GLU | D:337 | D:370 | 81.0 | NA | S | -94.6 | 4.8 | 81.0 | NA | NA | |||||||||||||
| 5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLU | D:365 | D:365 | 142.0 | 0.747 | T | 62.4 | -128.8 | 142.0 | 0.747 | 0.0 | ||||||
| 5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLU | D:365 | D:365 | 141.0 | 0.742 | T | 62.4 | -128.8 | 141.0 | 0.742 | 0.0 | ||||||
| 5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | C:365 | B:365 | 137.0 | NA | 360.0 | 4.1 | 137.0 | NA | NA | |||||||
| GLU | D:365 | D:365 | 136.0 | NA | 360.0 | 6.4 | 136.0 | NA | NA | ||||||||||||||
| 5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | C:365 | B:365 | 94.0 | NA | T | -78.8 | 10.0 | 94.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 137.0 | NA | 360.0 | 1.7 | 137.0 | NA | NA | ||||||||||||||
| 5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:365 | B:365 | 83.0 | NA | T | 62.0 | -141.7 | 83.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 82.0 | NA | T | 61.0 | -141.4 | 82.0 | NA | NA | |||||||||||||
| 5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:365 | B:365 | 82.0 | NA | T | 62.0 | -141.7 | 82.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 81.0 | NA | T | 61.1 | -141.4 | 81.0 | NA | NA | |||||||||||||
| 5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:365 | B:365 | 81.0 | NA | T | 62.0 | -141.7 | 81.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 82.0 | NA | T | 58.0 | -141.7 | 82.0 | NA | NA | |||||||||||||
| 5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:365 | B:365 | 82.0 | NA | T | 62.1 | -141.7 | 82.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 82.0 | NA | T | 61.0 | -141.4 | 82.0 | NA | NA | |||||||||||||
| 5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:365 | B:365 | 81.0 | NA | T | 62.0 | -141.6 | 81.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 82.0 | NA | T | 61.1 | -141.4 | 82.0 | NA | NA | |||||||||||||
| 5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:365 | B:365 | 81.0 | NA | T | 61.1 | -141.4 | 81.0 | NA | NA | ||||||
| GLU | D:365 | D:365 | 82.0 | NA | T | 61.0 | -141.4 | 82.0 | NA | NA | |||||||||||||
| 4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLU | B:346 | B:365 | 155.0 | 0.816 | T | -88.5 | 5.9 | 155.0 | 0.816 | 0.0 | ||||||
| GLU | D:346 | D:365 | 85.0 | NA | T | -87.8 | 5.0 | 85.0 | NA | NA | |||||||||||||
| 4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLU | B:346 | B:365 | 131.0 | 0.689 | T | 61.9 | -141.7 | 131.0 | 0.689 | 0.0 | ||||||
| GLU | D:346 | D:365 | 151.0 | 0.795 | T | 61.0 | -141.3 | 151.0 | 0.795 | 0.0 | |||||||||||||
| 5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLU | B:340 | B:370 | 143.0 | 0.753 | T | -87.3 | 8.1 | 143.0 | 0.753 | 0.0 |
HOH |
4.764 |
OE1 |
O |
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| GLU | D:340 | D:370 | 143.0 | 0.753 | T | -86.8 | 7.8 | NA | NA | NA | |||||||||||||
| 5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLU | B:340 | B:370 | 129.0 | 0.679 | T | -78.9 | 21.8 | 129.0 | 0.679 | 0.0 |
HOH |
5.909 |
OE1 |
O |
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| GLU | D:340 | D:370 | 129.0 | 0.679 | T | -78.5 | 21.0 | NA | NA | NA | |||||||||||||
| 5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLU | B:340 | B:370 | 138.0 | 0.726 | T | -84.1 | 0.6 | 138.0 | 0.726 | 0.0 |
HOH |
5.815 |
OE1 |
O |
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| GLU | D:340 | D:370 | 137.0 | 0.721 | T | -84.6 | 0.8 | NA | NA | NA | |||||||||||||
| 3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLU | B:340 | B:370 | 88.0 | NA | T | -86.5 | 7.2 | 88.0 | NA | NA | ||||||
| GLU | D:340 | D:370 | 93.0 | NA | T | -73.0 | 3.4 | 93.0 | NA | NA | |||||||||||||
| 3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLU | B:340 | B:370 | 86.0 | NA | T | -93.7 | 14.9 | 86.0 | NA | NA | ||||||
| GLU | D:340 | D:370 | 92.0 | NA | T | -74.4 | -9.4 | NA | NA | NA | |||||||||||||
| 5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | GLU | C:340 | C:370 | 128.0 | NA | 360.0 | -115.3 | 128.0 | NA | NA | |||||||
| GLU | E:340 | D:370 | 71.0 | NA | S | -73.9 | -160.8 | NA | NA | NA | |||||||||||||
| 3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLU | A:339 | A:370 | 86.0 | NA | T | -81.2 | 17.8 | 86.0 | NA | NA |
CL |
4.045 |
N |
CL |
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| 3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLU | A:339 | A:370 | 95.0 | NA | S | -72.8 | 4.0 | 95.0 | NA | NA | ||||||
| 6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 155.0 | 0.816 | T | -89.8 | 14.3 | 155.0 | 0.816 | 0.0 |
HOH |
6.518 |
O |
O |
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| GLU | D:339 | D:370 | 81.0 | NA | T | -87.5 | 12.9 | NA | NA | NA | |||||||||||||
| 6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 146.0 | 0.768 | T | -95.6 | 17.7 | 146.0 | 0.768 | 0.0 |
HOH |
8.084 |
O |
O |
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| GLU | D:339 | D:370 | 82.0 | NA | T | -93.3 | 12.7 | NA | NA | NA | |||||||||||||
| 6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 84.0 | NA | T | -79.1 | 2.3 | 84.0 | NA | NA |
HOH |
6.600 |
O |
O |
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| GLU | D:339 | D:370 | 84.0 | NA | T | -85.3 | 4.8 | NA | NA | NA | |||||||||||||
| 6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 144.0 | 0.758 | T | -99.4 | 4.6 | 144.0 | 0.758 | 0.0 |
HOH |
6.766 |
O |
O |
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| GLU | D:339 | D:370 | 78.0 | NA | T | -99.4 | 12.4 | NA | NA | NA | |||||||||||||
| 6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 146.0 | 0.768 | T | -85.5 | 11.1 | 146.0 | 0.768 | 0.0 |
HOH |
6.352 |
O |
O |
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| GLU | D:339 | D:370 | 79.0 | NA | T | -88.6 | 14.7 | NA | NA | NA | |||||||||||||
| 6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 159.0 | 0.837 | T | -92.3 | 15.1 | 159.0 | 0.837 | 0.0 |
HOH |
6.926 |
O |
O |
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| GLU | D:339 | D:370 | 79.0 | NA | T | -100.5 | 15.5 | NA | NA | NA | |||||||||||||
| 6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:339 | B:370 | 142.0 | 0.747 | T | -91.5 | 18.9 | 142.0 | 0.747 | 0.0 |
HOH |
6.491 |
O |
O |
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| GLU | D:339 | D:370 | 80.0 | NA | T | -94.6 | 21.2 | NA | NA | NA | |||||||||||||
| 5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | GLU | B:339 | D:370 | 86.0 | NA | T | -75.6 | 16.2 | 86.0 | NA | NA | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | GLU | A:370 | A:370 | 136.0 | 0.716 | T | -72.3 | 2.2 | |