Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13828725 | . | G | A | CCDS8662.1:NM_000834.3:c.1079cCg>cTg_NP_000825.2:p.360P>L | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | PRO | B:360 | B:360 | 22.0 | 0.152 | -67.2 | 147.9 | 22.0 | 0.152 | 0.0 | |||||||
PRO | D:360 | D:360 | 6.0 | 0.041 | -78.3 | 162.2 | 6.0 | 0.041 | 0.0 | ||||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | PRO | B:391 | B:360 | 9.0 | 0.062 | -87.6 | -176.2 | 9.0 | 0.062 | 0.0 |
NAG |
9.703 |
N |
O5 |
|||
PRO | D:391 | D:360 | 9.0 | 0.062 | -87.6 | -176.2 | 9.0 | 0.062 | 0.0 |
NAG |
9.702 |
N |
O5 |
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5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | PRO | B:335 | B:360 | 15.0 | NA | -73.4 | 144.8 | 15.0 | NA | NA | |||||||
PRO | D:335 | D:360 | 14.0 | NA | -73.4 | 144.7 | 14.0 | NA | NA | ||||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | PRO | B:335 | B:360 | 29.0 | NA | -76.6 | 155.5 | 29.0 | NA | NA | |||||||
PRO | D:335 | D:360 | 31.0 | NA | -76.6 | 155.5 | 31.0 | NA | NA | ||||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | PRO | B:335 | B:360 | 23.0 | NA | -72.3 | 176.2 | 23.0 | NA | NA | |||||||
PRO | D:335 | D:360 | 23.0 | NA | -72.3 | 176.2 | 23.0 | NA | NA | ||||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | PRO | B:335 | B:360 | 18.0 | NA | -78.7 | 159.3 | 18.0 | NA | NA | |||||||
PRO | D:335 | D:360 | 17.0 | NA | -78.7 | 159.3 | 17.0 | NA | NA | ||||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | PRO | B:335 | B:360 | 19.0 | NA | -66.9 | 142.4 | 19.0 | NA | NA | |||||||
PRO | D:335 | D:360 | 20.0 | NA | -66.8 | 142.3 | 20.0 | NA | NA | ||||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | PRO | B:391 | B:360 | 16.0 | 0.11 | -64.4 | 168.2 | 16.0 | 0.11 | 0.0 | |||||||
PRO | D:391 | D:360 | 17.0 | 0.117 | -64.4 | 168.2 | 17.0 | 0.117 | 0.0 | ||||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | PRO | B:391 | B:360 | 31.0 | 0.214 | -95.9 | 155.3 | 31.0 | 0.214 | 0.0 | |||||||
PRO | D:391 | D:360 | 33.0 | 0.228 | -96.0 | 155.4 | 33.0 | 0.228 | 0.0 | ||||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | PRO | B:391 | B:360 | 8.0 | 0.055 | -76.2 | 175.5 | 8.0 | 0.055 | 0.0 | |||||||
PRO | D:391 | D:360 | 6.0 | 0.041 | -76.2 | 175.6 | 6.0 | 0.041 | 0.0 | ||||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | PRO | B:391 | B:360 | 2.0 | 0.014 | -88.7 | 130.4 | 2.0 | 0.014 | 0.0 | |||||||
PRO | D:391 | D:360 | 2.0 | 0.014 | -88.7 | 130.4 | 2.0 | 0.014 | 0.0 | ||||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | PRO | B:391 | B:360 | 16.0 | 0.11 | -82.8 | 142.6 | 16.0 | 0.11 | 0.0 | |||||||
PRO | D:391 | D:360 | 11.0 | 0.076 | -83.9 | 145.3 | 11.0 | 0.076 | 0.0 | ||||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | PRO | B:391 | B:360 | 4.0 | 0.028 | -88.7 | 128.2 | 4.0 | 0.028 | 0.0 | |||||||
PRO | D:391 | D:360 | 3.0 | 0.021 | -88.7 | 128.2 | 3.0 | 0.021 | 0.0 | ||||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | PRO | B:391 | B:360 | 10.0 | 0.069 | -80.3 | 134.2 | 10.0 | 0.069 | 0.0 | |||||||
PRO | D:391 | D:360 | 4.0 | 0.028 | -82.3 | 156.3 | 4.0 | 0.028 | 0.0 | ||||||||||||||
6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | PRO | B:391 | B:360 | 14.0 | 0.097 | -67.0 | 165.6 | 14.0 | 0.097 | 0.0 | |||||||
PRO | D:391 | D:360 | 14.0 | 0.097 | -67.0 | 165.6 | 14.0 | 0.097 | 0.0 | ||||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | PRO | B:391 | B:360 | 13.0 | 0.09 | -89.8 | 129.0 | 13.0 | 0.09 | 0.0 | |||||||
PRO | D:391 | D:360 | 12.0 | 0.083 | -89.7 | 129.0 | 12.0 | 0.083 | 0.0 | ||||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | PRO | B:334 | B:360 | 19.0 | 0.131 | -86.6 | 146.8 | 19.0 | 0.131 | 0.0 | |||||||
PRO | D:334 | D:360 | 5.0 | 0.034 | -73.2 | 142.1 | 5.0 | 0.034 | 0.0 | ||||||||||||||
6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | PRO | B:327 | B:360 | 28.0 | 0.193 | -69.4 | 154.7 | 28.0 | 0.193 | 0.0 | |||||||
PRO | D:327 | D:360 | 26.0 | 0.179 | -69.4 | 154.7 | 26.0 | 0.179 | 0.0 | ||||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | PRO | D:355 | D:355 | 59.0 | 0.407 | -71.2 | 142.7 | 59.0 | 0.407 | 0.0 | |||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | PRO | D:355 | D:355 | 52.0 | 0.359 | -106.9 | 126.3 | 52.0 | 0.359 | 0.0 | |||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | C:355 | B:355 | 41.0 | NA | -78.3 | 148.9 | 41.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 37.0 | NA | -77.2 | 140.0 | 37.0 | NA | NA | ||||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | C:355 | B:355 | 29.0 | NA | -83.5 | 157.7 | 29.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 36.0 | NA | -81.0 | 151.9 | 36.0 | NA | NA | ||||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | B:355 | B:355 | 60.0 | NA | -64.2 | 153.7 | 60.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 63.0 | NA | -63.6 | 153.7 | 63.0 | NA | NA | ||||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | B:355 | B:355 | 61.0 | NA | -64.2 | 153.6 | 61.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 63.0 | NA | -63.5 | 153.8 | 63.0 | NA | NA | ||||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | B:355 | B:355 | 59.0 | NA | -64.3 | 153.6 | 59.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 64.0 | NA | -63.7 | 153.8 | 64.0 | NA | NA | ||||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | B:355 | B:355 | 61.0 | NA | -64.2 | 153.6 | 61.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 62.0 | NA | -63.6 | 153.8 | 62.0 | NA | NA | ||||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | B:355 | B:355 | 60.0 | NA | -64.2 | 153.6 | 60.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 62.0 | NA | -63.5 | 153.8 | 62.0 | NA | NA | ||||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | PRO | B:355 | B:355 | 36.0 | NA | -44.1 | 159.3 | 36.0 | NA | NA | |||||||
PRO | D:355 | D:355 | 40.0 | NA | -43.9 | 150.7 | 40.0 | NA | NA | ||||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | PRO | B:336 | B:355 | 6.0 | 0.041 | -79.3 | 154.6 | 6.0 | 0.041 | 0.0 | |||||||
PRO | D:336 | D:355 | 37.0 | 0.255 | -79.7 | 153.3 | 37.0 | 0.255 | 0.0 | ||||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | PRO | B:336 | B:355 | 31.0 | 0.214 | -64.2 | 153.6 | 31.0 | 0.214 | 0.0 | |||||||
PRO | D:336 | D:355 | 48.0 | 0.331 | -63.5 | 153.9 | 48.0 | 0.331 | 0.0 | ||||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | PRO | B:330 | B:360 | 5.0 | 0.034 | -81.9 | 154.2 | 5.0 | 0.034 | 0.0 |
HOH |
3.175 |
O |
O |
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PRO | D:330 | D:360 | 7.0 | 0.048 | -86.4 | 145.7 | NA | NA | NA | ||||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | PRO | B:330 | B:360 | 3.0 | 0.021 | -96.8 | 141.2 | 3.0 | 0.021 | 0.0 | |||||||
PRO | D:330 | D:360 | 7.0 | 0.048 | -88.0 | 156.3 | NA | NA | NA | ||||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | PRO | B:330 | B:360 | 6.0 | 0.041 | -81.2 | 153.9 | 6.0 | 0.041 | 0.0 |
HOH |
4.285 |
CA |
O |
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PRO | D:330 | D:360 | 10.0 | 0.069 | -79.1 | 150.5 | NA | NA | NA | ||||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | PRO | B:330 | B:360 | 3.0 | 0.021 | -73.2 | 141.9 | 3.0 | 0.021 | 0.0 |
HOH |
4.054 |
CD |
O |
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PRO | D:330 | D:360 | 9.0 | 0.062 | -87.7 | 147.2 | 9.0 | 0.062 | 0.0 | ||||||||||||||
3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | PRO | B:330 | B:360 | 2.0 | 0.014 | -87.7 | 158.4 | 2.0 | 0.014 | 0.0 | |||||||
PRO | D:330 | D:360 | 7.0 | 0.048 | -84.0 | 154.3 | NA | NA | NA | ||||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | PRO | C:330 | C:360 | 4.0 | 0.028 | -79.2 | 146.5 | 4.0 | 0.028 | 0.0 |
HOH |
9.286 |
CD |
O |
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PRO | E:330 | D:360 | 4.0 | 0.028 | -79.5 | 148.3 | NA | NA | NA | ||||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | PRO | A:329 | A:360 | 4.0 | 0.028 | -87.3 | 150.6 | 4.0 | 0.028 | 0.0 |
CL CL CL NA HOH |
9.740 8.882 8.346 7.464 4.429 |
CG CB C CG CD |
CL CL CL NA O |
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3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | PRO | A:329 | A:360 | 7.0 | 0.048 | -94.8 | 147.8 | 7.0 | 0.048 | 0.0 |
CL NA ZN |
9.612 7.539 6.088 |
CG CB CD |
CL NA ZN |
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6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 8.0 | 0.055 | -71.6 | 138.3 | 8.0 | 0.055 | 0.0 |
CL HOH |
9.999 4.103 |
CG CD |
CL O |
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PRO | D:329 | D:360 | 8.0 | 0.055 | -73.7 | 137.3 | NA | NA | NA | ||||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 6.0 | 0.041 | -78.9 | 139.7 | 6.0 | 0.041 | 0.0 |
HOH |
4.008 |
CG |
O |
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PRO | D:329 | D:360 | 6.0 | 0.041 | -80.7 | 137.8 | NA | NA | NA | ||||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 3.0 | 0.021 | -74.2 | 131.2 | 3.0 | 0.021 | 0.0 |
HOH |
4.040 |
CD |
O |
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PRO | D:329 | D:360 | 4.0 | 0.028 | -72.5 | 136.0 | NA | NA | NA | ||||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 8.0 | 0.055 | -75.8 | 144.3 | 8.0 | 0.055 | 0.0 |
HOH |
3.830 |
O |
O |
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PRO | D:329 | D:360 | 7.0 | 0.048 | -75.9 | 142.3 | NA | NA | NA | ||||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 8.0 | 0.055 | -84.7 | 135.0 | 8.0 | 0.055 | 0.0 |
CL HOH |
9.968 3.948 |
CG O |
CL O |
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PRO | D:329 | D:360 | 11.0 | 0.076 | -81.5 | 137.1 | NA | NA | NA | ||||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 8.0 | 0.055 | -75.8 | 138.0 | 8.0 | 0.055 | 0.0 |
HOH |
4.270 |
CD |
O |
|||
PRO | D:329 | D:360 | 10.0 | 0.069 | -71.7 | 139.3 | NA | NA | NA | ||||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | PRO | B:329 | B:360 | 9.0 | 0.062 | -78.4 | 139.0 | 9.0 | 0.062 | 0.0 |
HOH |
4.108 |
CD |
O |
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PRO | D:329 | D:360 | 13.0 | 0.09 | -76.0 | 139.1 | NA | NA | NA | ||||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | PRO | B:329 | D:360 | 25.0 | 0.172 | -86.5 | 179.1 | 25.0 | 0.172 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | PRO | A:360 | A:360 | 12.0 | 0.083 | -68.7 | 146.2 |